"Derma E - Advanced Peptides and Collagen Moisturizer" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Acetyl hexapeptide-8, panthenol and glycerin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (caprylic/capric triglyceride, dimethicone, cetyl alcohol, macadamia ternifolia seed oil and glyceryl stearate citrate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

We like that this moisturizer contains peptides (acetyl hexapeptide-8 0.45% - 1.10% and palmitoyl tripeptide-38 0.60% - 1.40%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
This formulation also uses an effective concentration of panthenol (pro-vitamin B5) - about 0.40% - 0.95%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Derma E" is cruelty free and so is its parent company.

Price

The product retails from 23.80$ up to 35.95$ in the United States and for 41.95A$ in Australia.

For a detailed price comparison: click here.

What can the product work for?

Does not work for

Evens skin tone

Anti-aging

What does the product description say?

Revolutionary double-action peptide cream to visibly soften and smooth the appearance of even the deepest wrinkles.

Source: Derma E

This product contains acetyl hexapeptide-8, palmitoyl tripeptide-38. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

acetyl hexapeptide-8 0.45% - 1.1%

Irritation risk:

Concentration: Effectiveness: MEDIUM

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

palmitoyl tripeptide-38 0.6% - 1.4%

Irritation risk:

Concentration: Effectiveness: MEDIUM

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

camellia sinensis leaf extract 0.15% - 0.55%

Irritation risk:

Concentration: Insufficient!

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

Moisturizing

What does the product description say?

Advanced Peptides and Collagen Moisturizer

Source: From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, palmitoyl tripeptide-38, panthenol

dimethicone 1.3% - 2%

Irritation risk:

Concentration: Effectiveness: HIGH

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

caprylic/capric triglyceride 2.8% - 4.1%

Irritation risk:

Concentration: Effectiveness: HIGH

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

glycerin 4.7% - 7.1%

Irritation risk:

Concentration: Effectiveness: HIGH

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

Anti-oxidation

This product contains antioxidants (pinus pinaster bark extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

pinus pinaster bark extract 0.35% - 0.85%

Irritation risk:

Concentration: Effectiveness: MEDIUM

A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)

aesculus hippocastanum seed extract 0.15% - 0.55%

Irritation risk:

Concentration: Effectiveness: LOW

Plant extract. Might have some anti-oxidant properties. Can be irritating

tocopherol 0.2% - 0.75%

Irritation risk:

Concentration: Insufficient!

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

Evens skin tone

What does the product description say?

Visibly improves the appearance of the skin's tone and texture.

Source: Derma E

This product contains ingredients (pinus pinaster bark extract) that could help reduce hyperpigmentation (for example, post-acne marks or age spots) in theory, but there is not enough evidence that they actually work.

pinus pinaster bark extract 0.35% - 0.85%

Irritation risk:

Concentration: Effectiveness: LOW

camellia sinensis leaf extract 0.15% - 0.55%

Irritation risk:

Concentration: Insufficient!

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Ingredients & concentrations

All ingredients

Key Actives

camellia sinensis leaf extract 0.15% - 0.55%

Irritation risk:

Works for: Anti-oxidation, Antibacterial, Anti-aging, Evens skin tone, Moisturizing, Anti-blemish

tocopherol 0.2% - 0.75%

Irritation risk:

Works for: Anti-oxidation, Moisturizing, Anti-inflammatory, Anti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

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Potential irritants

hamamelis virginiana bark/leaf extract 0.15% - 0.6%

Irritation risk:

aesculus hippocastanum seed extract 0.15% - 0.55%

Irritation risk:

Works for: Anti-oxidation

Plant extract. Might have some anti-oxidant properties. Can be irritating

Comodogenic ingredients

glyceryl stearate se 0.35% - 0.8%

Irritation risk: Comedogenicity: Medium

Works for: Cleansing, Moisturizing

Used to stabilize the product formulations and works as an emollient

All ingredients

water 40% - 60%

Irritation risk:

Plain old water

glycerin 4.7% - 7.1%

Irritation risk:

Works for: Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

macadamia ternifolia seed oil 3.7% - 5.5%

Irritation risk:

Works for: Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

Ingredient list view

Water, Glycerin, Macadamia ternifolia seed oil, Caprylic/capric triglyceride, Stearic acid, Cetyl alcohol, Glyceryl stearate citrate, Dimethicone, Hydroxypropyl cyclodextrin, Palmitoyl tripeptide-38, Acetyl hexapeptide-8, Panthenol, Pinus pinaster bark extract, Glyceryl stearate se, Acacia seyal gum extract, Unknown, Collagen, Tocopheryl acetate, Tocopherol, Ascorbyl palmitate, Hamamelis virginiana bark/leaf extract, Aesculus hippocastanum seed extract, Camellia sinensis leaf extract, Chamomilla recutita flower, Simmondsia chinensis seed oil, Allantoin, Xanthan gum, Potassium sorbate, Sodium hydroxide, Phenoxyethanol, Ethylhexylglycerin, Parfum, Unknown

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Price
WIMJ similarity score		53%	46%	44%	43%	43%	42%	42%	42%	42%	42%
Key ingredients	acetyl hexapeptide-8 palmitoyl tripeptide-38 +8 more	Common: acetyl hexapeptide-8 palmitoyl tripeptide-38 +6 more Other: acetyl tetrapeptide-11 urea +18 more	Common: palmitoyl tripeptide-38 panthenol +6 more Other: paraffinum liquidum copper tripeptide-1 +8 more	Common: palmitoyl tripeptide-38 panthenol +4 more Other: acetyl tetrapeptide-2 adenosine +11 more	Common: panthenol caprylic/capric triglyceride +3 more Other: avena sativa kernel extract algae extract +2 more	Common: panthenol caprylic/capric triglyceride +3 more Other: carthamus tinctorius seed oil	Common: panthenol acetyl hexapeptide-8 +3 more Other: carnosine copernicia cerifera wax +5 more	Common: acetyl hexapeptide-8 panthenol +3 more Other: urea trehalose +7 more	Common: acetyl hexapeptide-8 panthenol +3 more Other: urea trehalose +7 more	Common: panthenol caprylic/capric triglyceride +2 more Other: niacinamide ceramide np +6 more	Common: panthenol caprylic/capric triglyceride +2 more Other: ceramide 2 palmitoyl oligopeptide +7 more
Irritancy	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY LOW	IRRITANCY LOW	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY MEDIUM	IRRITANCY LOW	IRRITANCY LOW
Potential Irritants	parfum Has skin benefit? aesculus hippocastanum seed extract Has skin benefit? +10 more	echinacea angustifolia extract Has skin benefit? triacetin Has skin benefit? +16 more	parfum Has skin benefit? panax ginseng root extract Has skin benefit? +13 more	lavandula angustifolia oil Has skin benefit? citrus aurantium amara peel oil Has skin benefit? +12 more	caprylyl glycol Has skin benefit? glyceryl laurate Has skin benefit? +9 more	tocopheryl acetate Has skin benefit? simmondsia chinensis seed oil Has skin benefit? +3 more	acanthopanax senticosus root extract Has skin benefit? linalool Has skin benefit? +13 more	pullulan Has skin benefit? alcohol Has skin benefit? +7 more	pullulan Has skin benefit? alcohol Has skin benefit? +7 more	bht Has skin benefit? disodium edta Has skin benefit? +9 more	benzyl alcohol Has skin benefit? phosphatidylcholine Has skin benefit? +10 more
All ingredients	water Has skin benefit? glycerin Has skin benefit? +31 more	water Has skin benefit? caprylic/capric triglyceride Has skin benefit? +68 more	water Has skin benefit? glycerin Has skin benefit? +48 more	water Has skin benefit? glycerin Has skin benefit? +52 more	water Has skin benefit? glycerin Has skin benefit? +26 more	water Has skin benefit? aloe barbadensis leaf juice Has skin benefit? +19 more	water Has skin benefit? polyglyceryl-3 polyricinoleate Has skin benefit? +41 more	water Has skin benefit? glycerin Has skin benefit? +34 more	water Has skin benefit? glycerin Has skin benefit? +34 more	water Has skin benefit? caprylic/capric triglyceride Has skin benefit? +29 more	water Has skin benefit? caprylic/capric triglyceride Has skin benefit? +36 more

PRODUCT REVIEW

Derma E Advanced Peptides and Collagen Moisturizer

Works for:

Doesn't work for:

Can it cause trouble?

Key actives

Cheaper alternatives

Product summary

Ingredient callouts

Irritation risk

About the brand

Price

What can the product work for?

Works for

Does not work for

Anti-aging

What does the product description say?

Moisturizing

What does the product description say?

Anti-oxidation

Evens skin tone

What does the product description say?

Honesty check

How honest is this product?

Buy now

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Can it cause trouble?

Potential irritants

Comodogenic ingredients

User reviews (0)

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Ingredients & concentrations

All ingredients

Key Actives

Potential irritants

Comodogenic ingredients

All ingredients

Ingredient list view

Sources