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Product summary

Based on the ingredients included, "Darphin - Predermine Anti Wrinkle Cream" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (acetyl glucosamine, acetyl hexapeptide-8, algae extract, biosaccharide gum-1 and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, algae extract, oryza sativa bran oil and butyrospermum parkii butter) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We like that this moisturizer contains peptides (acetyl hexapeptide-8 0.30% - 0.50%, palmitoyl tetrapeptide-7 0.40% - 0.60% and palmitoyl tripeptide-1 0.40% - 0.65%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: benzophenone-4, lecithin, caprylic/capric triglyceride and sigesbeckia orientalis extract

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 221.64CA$ in Canada, for 150.63A$ in Australia, for 98.70$ in the United States and from 71.33£ up to 80.36£ in the United Kingdom.

For a detailed price comparison: click here.