Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Evens skin tone
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 7
Key actives
Product Summary
Based on the ingredients included, "Darphin - Predermine Anti Wrinkle Cream" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (acetyl glucosamine, acetyl hexapeptide-8, algae extract, biosaccharide gum-1 and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, algae extract, oryza sativa bran oil and butyrospermum parkii butter) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- We like that this moisturizer contains peptides (acetyl hexapeptide-8 0.30% - 0.50%, palmitoyl tetrapeptide-7 0.40% - 0.60% and palmitoyl tripeptide-1 0.40% - 0.65%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 221.64CA$ in Canada, for 150.63A$ in Australia, for 98.70$ in the United States and from 71.33£ up to 80.36£ in the United Kingdom.
For a detailed price comparison: click here.
Works for
Anti-aging
What does the product description say?
Predermine Anti Wrinkle Cream
Source: From product name
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, arabidopsis thaliana extract, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin
Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycine soja protein.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin
A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking
Moisturizing
What does the product description say?
Predermine Anti Wrinkle Cream
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
algae extract, biosaccharide gum-1.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, helianthus annuus seed oil.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1
Helps soften the upper layer of the skin and might have some anti-oxidant properties
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
An emollient that helps soften the skin and create a nice product texture
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Helps to soften the upper layer of the skin without creating a greasy texture
Helps soften the upper layer of the skin. It mostly contains oleic acid which is not the most effective emollient to prevent water loss, but might have an anti-inflammatory effect
A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking
An oil from a mixture of different vegetables. Helps soften the upper layer of the skin
Used to create a thicker product consistency and soften the upper layer of the skin
Helps to soften the upper layer of the skin and create a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps preserve products and creates a nice product texture
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
An emollient that helps soften the upper layer of the skin
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect
Might help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Darphin Predermine Anti Wrinkle Cream | Current | $80.36 | |
Clinique Smart Clinical Repair Wrinkle Cream All Skin Types | 58% | $63.00 | |
NEOGEN X SUR.MEDIC Surmedic 24K Gold Caviar Repair Vital Cream | 52% | $39.59 | |
 Peter Thomas Roth Peptide 21 Lift & Firm Moisturizer | 50% | $80.00 |
Key Actives
An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
A plant extract that can contain an anti-inflammatory compound
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps soften the upper layer of the skin and might have some anti-oxidant properties
Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritating
Potential irritants
A plant extract that might have anti-oxidant properties. Can be irritating
A plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritating
An aromatic blend of unspecified and possibly irritating ingredients
A fragrance. Potential allergen and can be irritating
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
Used to create a thicker product consistency and soften the upper layer of the skin
A plant extract that can contain an anti-inflammatory compound
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten
Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect
Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking
Helps preserve products and creates a nice product texture
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Used to stabilize the product formulation
Helps water and oil mix together. Could be an allergen (beeswax)
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
Helps create a thicker product consistency. Might be irritating
Comedogenic ingredients
An oil from a mixture of different vegetables. Helps soften the upper layer of the skin
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Might help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing
An emollient that helps soften the skin and create a nice product texture
A great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
All ingredients
An oil from a mixture of different vegetables. Helps soften the upper layer of the skin
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
Helps oil and water mix togehter and creates a nice product texture
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
Helps to soften the upper layer of the skin and create a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Used to create a thicker product consistency and soften the upper layer of the skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
A plant extract that can contain an anti-inflammatory compound
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps soften the upper layer of the skin and might have some anti-oxidant properties
Helps soften the upper layer of the skin. It mostly contains oleic acid which is not the most effective emollient to prevent water loss, but might have an anti-inflammatory effect
A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten
A plant extract that might have anti-oxidant properties. Can be irritating
Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect
A plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking
Might help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
An emollient that helps soften the upper layer of the skin
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
An emollient that helps soften the skin and create a nice product texture
Helps to soften the upper layer of the skin without creating a greasy texture
Helps preserve products and creates a nice product texture
An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin
A great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
Used to stabilize the product formulation
Helps water and oil mix together. Could be an allergen (beeswax)
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritating
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
Helps create a thicker product consistency. Might be irritating
An aromatic blend of unspecified and possibly irritating ingredients
A fragrance. Potential allergen and can be irritating
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
A preservative. It helps prevent bacterial growth in cosmetic products
Ingredient list view
Water, Hydrogenated vegetable oil, Simmondsia chinensis seed oil, Glyceryl stearate, Peg-100 stearate, Butyrospermum parkii butter, Glycerin, Cetearyl alcohol, Propanediol, Hydrogenated polydecene, Butylene glycol, Tridecyl trimellitate, Triisostearin, Squalane, Sigesbeckia orientalis extract, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Acetyl hexapeptide-8, Iris florentina root extract, Sodium hyaluronate, Oryza sativa bran extract, Oryza sativa bran oil, Garcinia indica seed butter, Glycine soja protein, Tocopheryl acetate, Hordeum vulgare extract, Equisetum arvense extract, Cucumis sativus fruit extract, Hibiscus sabdariffa flower extract, Menyanthes trifoliata leaf extract, Rosmarinus officinalis leaf extract, Arabidopsis thaliana extract, Padina pavonica thallus extract, Helianthus annuus seed oil, Propylene glycol dicaprate, Biosaccharide gum-1, Pca dimethicone, Ethylhexyl palmitate, Coco-caprylate/caprate, Caprylyl glycol, Helianthus annuus seed extract, Acetyl glucosamine, Butyrospermum parkii butter unsaponifiables, Caffeine, Caprylic/capric triglyceride, Algae extract, Diethylhexyl syringylidenemalonate, Polyglyceryl-3 beeswax, Beheneth-25, Acrylates/c10-30 alkyl acrylate crosspolymer, Polysorbate 20, Lecithin, Xanthan gum, Benzophenone-4, Sodium hydroxide, Hexylene glycol, Silica dimethyl silylate, Carbomer, Calcium chloride, Parfum, Citronellol, Alpha-isomethyl ionone, Benzyl salicylate, Hydroxycitronellal, Geraniol, Linalool, Limonene, Hexyl cinnamal, Coumarin, Citral, Amyl cinnamal, Tetrasodium edta, Phenoxyethanol, Potassium sorbate, Chlorphenesin, Unknown, Ci 60730, Ci 14700
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