Darphin

Darphin Predermine Anti Wrinkle Cream

Name: Darphin - Predermine Anti Wrinkle Cream
Brand: Darphin

Efficacy100/100IrritancyHigh

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Works for

2 of 2 advertised claims delivered

Anti-aging

8 ingredients credited for this claim

Strong support

What the product description says

“Predermine Anti Wrinkle Cream”

From product name

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, arabidopsis thaliana extract, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%

Arabidopsis thaliana extractKey activeEffect: MediumPlant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking~0.25–0.45%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.65%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.25–0.45%

Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.9–2.3%

Algae extractEffect: LowPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.3–0.55%

Moisturizing

30 ingredients credited for this claim

Strong support

What the product description says

“Predermine Anti Wrinkle Cream”

From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: algae extract, biosaccharide gum-1.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1

Oryza sativa bran oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and might have some anti-oxidant properties~0.25–0.45%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.25–0.5%

Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.6–2%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%

Algae extractKey active· Humectant, EmollientEffect: HighPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.3–0.55%

Biosaccharide gum-1Key active· HumectantEffect: HighHelps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin~0.25–0.45%

Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~4.2–5.1%

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.9–2.3%

Butyrospermum parkii butter unsaponifiablesKey activeEffect: HighA great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.25–0.45%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.65%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.45–0.7%

Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.3–0.5%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.4–1.7%

Coco-caprylate/caprateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin without creating a greasy texture~0.25–0.5%

Garcinia indica seed butterKey activeEffect: MediumHelps soften the upper layer of the skin. It mostly contains oleic acid which is not the most effective emollient to prevent water loss, but might have an anti-inflammatory effect~0.2–0.35%

Glycine soja proteinKey active· Humectant, EmollientEffect: MediumA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.25–0.45%

Hydrogenated vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~3.8–4.7%

Tridecyl trimellitate· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~0.55–0.8%

Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~0.8–1.2%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.6–0.95%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.7–3.3%

Propylene glycol dicaprate· EmollientEffect: LowAn emollient that helps soften the upper layer of the skin~0.25–0.5%

Caprylic/capric triglycerideUnder-dosedEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.3–0.55%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.5%

Cucumis sativus fruit extractEffect: Low, below effective doseMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect~0.25–0.45%

Padina pavonica thallus extractEffect: Low, below effective doseMight help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing~0.25–0.45%

Evens skin tone

Not advertised by the brand · 2 ingredients credited for this claim

Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycine soja protein.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Can it cause trouble?

Irritancy

16 strong irritants: Equisetum arvense extract, Hibiscus sabdariffa flower extract + 14 more — patch-test recommended

High risk

We flagged 35 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Equisetum arvense extractA plant extract that might have anti-oxidant properties. Can be irritatingHigh~0.25–0.45%est.

Hibiscus sabdariffa flower extractA plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicalsHigh~0.25–0.45%est.

Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.2–0.4%est.

Benzophenone-4Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritatingHigh~0.45–0.65%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.2–0.4%est.

CitronellolA fragrance. Can be irritatingHigh~0.2–0.4%est.

Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.2–0.4%est.

Benzyl salicylateA fragrance. Is a likely irritantHigh~0.2–0.4%est.

HydroxycitronellalA fragrance. A likely allergen and can be irritatingHigh~0.2–0.4%est.

GeraniolA fragrance. Can be irritatingHigh~0.2–0.4%est.

LinaloolA fragrance. Can be irritatingHigh~0.2–0.4%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.2–0.35%est.

Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.2–0.35%est.

CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.2–0.35%est.

CitralA fragrance with a lemon scent. A likely irritantHigh~0.15–0.3%est.

Amyl cinnamal—High~0.15–0.3%est.

Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~4.2–5.1%est.

Tridecyl trimellitateUsed to create a thicker product consistency and soften the upper layer of the skinMedium~0.55–0.8%est.

Sigesbeckia orientalis extractA plant extract that can contain an anti-inflammatory compoundMedium~0.3–0.6%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.2–0.4%est.

Hordeum vulgare extractA plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to glutenMedium~0.25–0.45%est.

Cucumis sativus fruit extractMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effectMedium~0.25–0.45%est.

Arabidopsis thaliana extractPlant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lackingMedium~0.25–0.45%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.

CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.25–0.45%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.3–0.55%est.

Diethylhexyl syringylidenemalonateUsed to stabilize the product formulationMedium~0.25–0.45%est.

Polyglyceryl-3 beeswaxHelps water and oil mix together. Could be an allergen (beeswax)Medium~0.25–0.5%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.25–0.5%est.

Hexylene glycolHelps create a more spreadable product textureMedium~0.25–0.45%est.

Calcium chlorideHelps create a thicker product consistency. Might be irritatingMedium~0.25–0.45%est.

Tetrasodium edtaHelps to stabilize the product formulationMedium~0.15–0.3%est.

Potassium sorbateA preservativeMedium~0.1–0.2%est.

ChlorphenesinA preservativeMedium~0.1–0.2%est.

Ci 14700A colorantMedium~0.05–0.1%est.

Comedogenic

7 ingredients rated 2 or more on the 0–5 pore-clogging scale

7 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.9–2.3%est.

Padina pavonica thallus extractMight help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing3/5~0.25–0.45%est.

Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.3–0.5%est.

Algae extractPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet3/5~0.3–0.55%est.

Hydrogenated vegetable oilAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin2/5~3.8–4.7%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.4–1.7%est.

Butyrospermum parkii butter unsaponifiablesA great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals2/5~0.25–0.45%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Hydrogenated vegetable oil~3.8–4.7%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Hydrogenated vegetable oil

Simmondsia chinensis seed oil~4.2–5.1%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil

Glyceryl stearate~2.7–3.3%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Peg-100 stearate~2.4–2.9%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate

Butyrospermum parkii butter~1.9–2.3%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Glycerin~1.6–2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Cetearyl alcohol~1.4–1.7%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Propanediol~1.1–1.3%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Hydrogenated polydecene~0.8–1.2%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene

Butylene glycol~0.6–0.95%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Tridecyl trimellitate~0.55–0.8%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tridecyl trimellitate

Triisostearin~0.45–0.65%

Formula

Irritation risk: Low

More about Triisostearin

Squalane~0.45–0.7%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Sigesbeckia orientalis extract~0.3–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Anti-inflammatory

A plant extract that can contain an anti-inflammatory compound

More about Sigesbeckia orientalis extract

Palmitoyl tripeptide-1~0.4–0.65%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Palmitoyl tetrapeptide-7~0.4–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Acetyl hexapeptide-8~0.3–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Iris florentina root extract~0.25–0.5%

Formula

Irritation risk: Low

More about Iris florentina root extract

Sodium hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Oryza sativa bran extract~0.2–0.4%

Formula

Irritation risk: Low

Used to thicken the product consistency

More about Oryza sativa bran extract

Oryza sativa bran oil~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and might have some anti-oxidant properties

More about Oryza sativa bran oil

Garcinia indica seed butter~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin. It mostly contains oleic acid which is not the most effective emollient to prevent water loss, but might have an anti-inflammatory effect

More about Garcinia indica seed butter

Glycine soja protein~0.25–0.45%

Key active

Irritation risk: Low

Works for

CleansingMoisturizingAnti-agingEvens skin toneAnti-oxidation

A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking

More about Glycine soja protein

Tocopheryl acetate~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Hordeum vulgare extract~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten

More about Hordeum vulgare extract

Equisetum arvense extract~0.25–0.45%

Irritant · high

Irritation risk: High

A plant extract that might have anti-oxidant properties. Can be irritating

More about Equisetum arvense extract

Cucumis sativus fruit extract~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect

More about Cucumis sativus fruit extract

Hibiscus sabdariffa flower extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals

More about Hibiscus sabdariffa flower extract

Menyanthes trifoliata leaf extract~0.25–0.45%

Formula

Irritation risk: Low

More about Menyanthes trifoliata leaf extract

Rosmarinus officinalis leaf extract~0.2–0.4%

Irritant · high

Irritation risk: High

Works for

Anti-blemishAntibacterialAnti-oxidation

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract

Arabidopsis thaliana extract~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-aging

Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking

More about Arabidopsis thaliana extract

Padina pavonica thallus extract~0.25–0.45%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

Might help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing

More about Padina pavonica thallus extract

Helianthus annuus seed oil~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Propylene glycol dicaprate~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the upper layer of the skin

More about Propylene glycol dicaprate

Biosaccharide gum-1~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin

More about Biosaccharide gum-1

Pca dimethicone~0.25–0.45%

Formula

Irritation risk: Low

More about Pca dimethicone

Ethylhexyl palmitate~0.3–0.5%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate

Coco-caprylate/caprate~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin without creating a greasy texture

More about Coco-caprylate/caprate

Caprylyl glycol~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Helianthus annuus seed extract~0.25–0.45%

Formula

Irritation risk: Low

More about Helianthus annuus seed extract

Acetyl glucosamine~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingEvens skin toneAnti-agingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine

Butyrospermum parkii butter unsaponifiables~0.25–0.45%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

MoisturizingAnti-oxidation

A great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter unsaponifiables

Caffeine~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Caprylic/capric triglyceride~0.3–0.55%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Algae extract~0.3–0.55%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-aging

Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet

More about Algae extract

Diethylhexyl syringylidenemalonate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Used to stabilize the product formulation

More about Diethylhexyl syringylidenemalonate

Polyglyceryl-3 beeswax~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together. Could be an allergen (beeswax)

More about Polyglyceryl-3 beeswax

Beheneth-25~0.3–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

More about Beheneth-25

Acrylates/c10-30 alkyl acrylate crosspolymer~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Polysorbate 20~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Lecithin~0.3–0.5%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Xanthan gum~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Benzophenone-4~0.45–0.65%

Irritant · high

Irritation risk: High

Works for

Sun protection

Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritating

More about Benzophenone-4

Sodium hydroxide~0.25–0.45%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Hexylene glycol~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol

Silica dimethyl silylate~0.25–0.5%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Silica dimethyl silylate

Carbomer~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Calcium chloride~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Helps create a thicker product consistency. Might be irritating

More about Calcium chloride

Parfum~0.2–0.4%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Citronellol~0.2–0.4%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Citronellol

Alpha-isomethyl ionone~0.2–0.4%

Irritant · high

Irritation risk: High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone

Benzyl salicylate~0.2–0.4%

Irritant · high

Irritation risk: High

A fragrance. Is a likely irritant

More about Benzyl salicylate

Hydroxycitronellal~0.2–0.4%

Irritant · high

Irritation risk: High

A fragrance. A likely allergen and can be irritating

More about Hydroxycitronellal

Geraniol~0.2–0.4%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Geraniol

Linalool~0.2–0.4%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Limonene~0.2–0.35%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Hexyl cinnamal~0.2–0.35%

Irritant · high

Irritation risk: High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal

Coumarin~0.2–0.35%

Irritant · high

Irritation risk: High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin

Citral~0.15–0.3%

Irritant · high

Irritation risk: High

A fragrance with a lemon scent. A likely irritant

More about Citral

Amyl cinnamal~0.15–0.3%

Irritant · high

Irritation risk: High

More about Amyl cinnamal

Tetrasodium edta~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Helps to stabilize the product formulation

More about Tetrasodium edta

Phenoxyethanol~0.15–0.25%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Potassium sorbate~0.1–0.2%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Chlorphenesin~0.1–0.2%

Irritant · medium

Irritation risk: Medium

A preservative

More about Chlorphenesin

Ext. violet 2

Not recognized

Ci 60730~0.05–0.15%

Formula

Irritation risk: Low

More about Ci 60730

Ci 14700~0.05–0.1%

Irritant · medium

Irritation risk: Medium

A colorant

More about Ci 14700

Ingredient list view

Water, Hydrogenated vegetable oil, Simmondsia chinensis seed oil, Glyceryl stearate, Peg-100 stearate, Butyrospermum parkii butter, Glycerin, Cetearyl alcohol, Propanediol, Hydrogenated polydecene, Butylene glycol, Tridecyl trimellitate, Triisostearin, Squalane, Sigesbeckia orientalis extract, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Acetyl hexapeptide-8, Iris florentina root extract, Sodium hyaluronate, Oryza sativa bran extract, Oryza sativa bran oil, Garcinia indica seed butter, Glycine soja protein, Tocopheryl acetate, Hordeum vulgare extract, Equisetum arvense extract, Cucumis sativus fruit extract, Hibiscus sabdariffa flower extract, Menyanthes trifoliata leaf extract, Rosmarinus officinalis leaf extract, Arabidopsis thaliana extract, Padina pavonica thallus extract, Helianthus annuus seed oil, Propylene glycol dicaprate, Biosaccharide gum-1, Pca dimethicone, Ethylhexyl palmitate, Coco-caprylate/caprate, Caprylyl glycol, Helianthus annuus seed extract, Acetyl glucosamine, Butyrospermum parkii butter unsaponifiables, Caffeine, Caprylic/capric triglyceride, Algae extract, Diethylhexyl syringylidenemalonate, Polyglyceryl-3 beeswax, Beheneth-25, Acrylates/c10-30 alkyl acrylate crosspolymer, Polysorbate 20, Lecithin, Xanthan gum, Benzophenone-4, Sodium hydroxide, Hexylene glycol, Silica dimethyl silylate, Carbomer, Calcium chloride, Parfum, Citronellol, Alpha-isomethyl ionone, Benzyl salicylate, Hydroxycitronellal, Geraniol, Linalool, Limonene, Hexyl cinnamal, Coumarin, Citral, Amyl cinnamal, Tetrasodium edta, Phenoxyethanol, Potassium sorbate, Chlorphenesin, Unknown, Ci 60730, Ci 14700

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	DarphinPredermine Anti Wrinkle CreamYOUR PRODUCT	CliniqueSmart Clinical Repair Wrinkle Cream All Skin Types	NEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream	Peter Thomas RothPEPTIDE 21 WRINKLE RESIST MOISTURISER - Day care
Match	—	58%	52%	50%
Price	$106.24	$78.00−$28.24	$39.59−$66.65	—
Shared key ingredients	—	9 of 20	9 of 20	8 of 20
Key difference	—	Acetyl Octapeptide-3	Copper Tripeptide-1	Tripeptide-1
Irritancy	High	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

Based on the ingredients included, "Darphin - Predermine Anti Wrinkle Cream" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (acetyl glucosamine, acetyl hexapeptide-8, algae extract, biosaccharide gum-1 and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, algae extract, oryza sativa bran oil and butyrospermum parkii butter) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

We like that this moisturizer contains peptides (acetyl hexapeptide-8 0.30% - 0.50%, palmitoyl tetrapeptide-7 0.40% - 0.60% and palmitoyl tripeptide-1 0.40% - 0.65%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: benzophenone-4, lecithin, caprylic/capric triglyceride and sigesbeckia orientalis extract

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 221.64CA$ in Canada, for 150.63A$ in Australia, for 98.70$ in the United States and from 71.33£ up to 80.36£ in the United Kingdom.

For a detailed price comparison: click here.