Clinique Dramatically Different Moisturizing Lotion+ Tube

Clinique Dramatically Different Moisturizing Lotion+ Tube

Efficacy100/100IrritancyLow
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Works for

1 of 1 advertised claim delivered

Moisturizing
13 ingredients credited for this claim
Strong support
What the product description says
“Dramatically Different Moisturizing Lotion+ Tube”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: sesamum indicum seed oil, glyceryl stearate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: paraffinum liquidum, petrolatum, urea

UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~1.2–1.8%
PetrolatumHero· Emollient, OcclusiveEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~2.8–4.2%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.6–5.4%
Sesamum indicum seed oilKey active· EmollientEffect: HighA good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function~1.5–2.2%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.75%
Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~6.2–9.3%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.15–0.65%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.8–2.6%
Lanolin alcohol· EmollientEffect: LowHelps oil and water mix together. Can be irritating~1–1.5%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.15–0.6%
Propylene glycol dicaprate· EmollientEffect: LowAn emollient that helps soften the upper layer of the skin~0.35–0.85%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~2.2–3.3%
Cucumis sativus fruit extractEffect: Low, below effective doseMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect~0.45–1.05%

Can it cause trouble?

Irritancy
8 flagged ingredients
Low risk
We flag 8 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Ci 15985A colorantHigh~0.05–0.2%est.
Ci 19140A yellow dyeHigh~0.05–0.15%est.
Lanolin alcoholHelps oil and water mix together. Can be irritatingMedium~1–1.5%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.85–1.25%est.
Hordeum vulgare extractA plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to glutenMedium~0.55–1.3%est.
Cucumis sativus fruit extractMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effectMedium~0.45–1.05%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.15–0.65%est.
Ci 17200A red colorantMedium~0.05–0.1%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Paraffinum liquidum~6.2–9.3%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Glycerin~3.6–5.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Petrolatum~2.8–4.2%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Stearic acid~2.2–3.3%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Glyceryl stearate~1.8–2.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Sesamum indicum seed oil~1.5–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

A good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function

More about Sesamum indicum seed oil
Urea~1.2–1.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Lanolin alcohol~1–1.5%
Irritant · medium
Irritation risk
Medium
Works for
CleansingMoisturizing

Helps oil and water mix together. Can be irritating

More about Lanolin alcohol
Triethanolamine~0.85–1.25%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Hordeum vulgare extract~0.55–1.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten

More about Hordeum vulgare extract
Cucumis sativus fruit extract~0.45–1.05%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizing

Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect

More about Cucumis sativus fruit extract
Helianthus annuus seedcake~0.5–1.2%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Helianthus annuus seedcake
Propylene glycol dicaprate~0.35–0.85%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the upper layer of the skin

More about Propylene glycol dicaprate
Sodium hyaluronate~0.2–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Butylene glycol~0.15–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Pentylene glycol~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Trisodium edta~0.1–0.4%
Formula
Irritation risk
Low

Helps preserve product formulations

More about Trisodium edta
Phenoxyethanol~0.1–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ci 15985~0.05–0.2%
Irritant · high
Irritation risk
High

A colorant

More about Ci 15985
Ci 19140~0.05–0.15%
Irritant · high
Irritation risk
High

A yellow dye

More about Ci 19140
Ci 17200~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A red colorant

More about Ci 17200
Ingredient list view

Water, Paraffinum liquidum, Glycerin, Petrolatum, Stearic acid, Glyceryl stearate, Sesamum indicum seed oil, Urea, Lanolin alcohol, Triethanolamine, Hordeum vulgare extract, Cucumis sativus fruit extract, Helianthus annuus seedcake, Propylene glycol dicaprate, Sodium hyaluronate, Butylene glycol, Pentylene glycol, Trisodium edta, Phenoxyethanol, Ci 15985, Ci 19140, Ci 17200

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Amazon UKPrice as of 10/3/2026 15:55 GMT
≈ $24.79
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
CliniqueDramatically Different Moisturizing Lotion+ TubeYOUR PRODUCTAqua CareLotion for Dry Skin with 10% UreaBootsSkin Clear Lotion with niacinamideNeutrogenaHypoallergenic Body Lotion Dryskin
Match—55%53%52%
Price$15.99$10.39−$5.60$5.29−$10.70—
Shared key ingredients—3 of 64 of 63 of 6
Key difference—Lactic AcidNiacinamideDimethicone
Irritancy Low Low Low Low
Drying alcohol————
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Product summary

"Clinique - Dramatically Different Moisturizing Lotion+ Tube" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Urea, glycerin, sodium hyaluronate and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (paraffinum liquidum, petrolatum, sesamum indicum seed oil, glyceryl stearate and lanolin alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 28.00$ in the United States and for 20.98£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 14 studies and safety reviews.

  1. 1
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  6. 6
    Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
Clinique Dramatically Different Moisturizing Lotion+ Tube
CliniqueDramatically Different Moisturizing Lotion+ Tube

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As an Amazon Associate, WIMJ earns from qualifying purchases.