Clinicians Complex C-Plus Antioxidant Cream

Clinicians Complex C-Plus Antioxidant Cream

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Anti-aging
4 ingredients credited for this claim
Strong support
What the product description says
“The formula also helps to protect the skin against the damaging effects of free radicals, minimizing the appearance of fine lines and wrinkles.”
Source: Lookfantastic US

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains ascorbic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Ascorbic acidHeroEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~5.1–6.2%
TocopherolEffect: LowPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.9–2.3%
Ascorbyl palmitateEffect: LowBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~7–8.5%
Retinyl palmitateUnder-dosedEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.2–0.35%
Moisturizing
13 ingredients credited for this claim
Strong support
What the product description says
“C-Plus Antioxidant Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: cyclomethicone, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 1

Ceramide 1Hero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.45–0.65%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.35–0.65%
CyclomethiconeKey active· Humectant, EmollientEffect: HighA type of silicone that leaves a nice silky finish on the skin and can help soften its upper layer~0.2–0.35%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.5–0.75%
GlycosphingolipidsKey active· EmollientEffect: HighA type of lipids naturally present in skin. They can be converted to ceramides in skin~0.45–0.65%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.65–0.95%
SphingolipidsKey active· EmollientEffect: HighSphingolipids are a group of lipids with a common chemical structure. Some of them are naturally present in skin and can be converted to ceramides~0.45–0.65%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.3–0.55%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~1.2–1.5%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~1.7–2.1%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.45–0.7%
TocopherolEffect: LowPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.9–2.3%
PetrolatumUnder-dosedEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~1.6–1.9%
Anti-oxidation
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product contains antioxidants (ascorbic acid, tocopherol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Ascorbic acidHeroEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~5.1–6.2%
TocopherolKey activeEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.9–2.3%
Tocopheryl acetateEffect: LowA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~2.1–2.6%
Ascorbyl palmitateEffect: LowBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~7–8.5%
Evens skin tone
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: ascorbic acid.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Ascorbic acidHeroEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~5.1–6.2%
Retinyl palmitateUnder-dosedEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.2–0.35%

Can it cause trouble?

Irritancy
2 strong irritants: Retinyl palmitate, Diazolidinyl urea
Medium risk
We flagged 8 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~5.1–6.2%est.
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.2–0.35%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.15–0.25%est.
Diazolidinyl ureaA preservative. Works by releasing formaldehyde. Can be irritatingHigh~0.1–0.2%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~7–8.5%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~2.1–2.6%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~0.45–0.7%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.4%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~1.2–1.5%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.45–0.7%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~1.7–2.1%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Ascorbyl palmitate~7–8.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-aging

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Ascorbic acid~5.1–6.2%
Hero · Anti-aging, Anti-oxidation, Evens skin toneIrritant · high
Irritation risk
High
Works for
Anti-agingAnti-oxidationEvens skin tone

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Glucosamine~3.5–4.3%
Formula
Irritation risk
Low
More about Glucosamine
Unspecified form of vitamin c~2.9–3.5%
Formula
Complex
Not recognized
Tocopheryl acetate~2.1–2.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Tocopherol~1.9–2.3%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Glyceryl stearate se~1.7–2.1%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Petrolatum~1.6–1.9%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Ethylhexyl palmitate~1.2–1.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Polysorbate 20~0.75–1.15%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Helianthus annuus seed oil~0.65–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Glycerin~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Isopropyl palmitate~0.45–0.7%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Ceramide 1~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide 1
Sphingolipids~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Sphingolipids are a group of lipids with a common chemical structure. Some of them are naturally present in skin and can be converted to ceramides

More about Sphingolipids
Glycosphingolipids~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of lipids naturally present in skin. They can be converted to ceramides in skin

More about Glycosphingolipids
Cholesterol~0.35–0.65%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol
Squalane~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Citric acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Retinyl palmitate~0.2–0.35%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-blemishExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Usp (vitamin a)
Not recognized
Cyclomethicone~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that leaves a nice silky finish on the skin and can help soften its upper layer

More about Cyclomethicone
Propylene glycol~0.15–0.25%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Diazolidinyl urea~0.1–0.2%
Irritant · high
Irritation risk
High

A preservative. Works by releasing formaldehyde. Can be irritating

More about Diazolidinyl urea
Methylparaben~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Methylparaben
Propylparaben~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Propylparaben
Ingredient list view

Water, Ascorbyl palmitate, Ascorbic acid, Glucosamine, Unspecified form of vitamin c, Unknown, Tocopheryl acetate, Tocopherol, Glyceryl stearate se, Petrolatum, Ethylhexyl palmitate, Polysorbate 20, Helianthus annuus seed oil, Glycerin, Isopropyl palmitate, Ceramide 1, Sphingolipids, Glycosphingolipids, Cholesterol, Squalane, Citric acid, Retinyl palmitate, Unknown, Cyclomethicone, Propylene glycol, Diazolidinyl urea, Methylparaben, Propylparaben

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Lookfantastic US
$75.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Clinicians ComplexC-Plus Antioxidant CreamYOUR PRODUCTCitrix15% CreamReform SkincareEveryday Moisturiserd'AlbaWhite Truffle Intensive Nourishing Cream
Match—70%70%67%
Price$70.00$92.40+$22.40$46.21−$23.79$32.99−$37.01
Shared key ingredients—2 of 123 of 121 of 12
Key difference—DimethiconeFerulic AcidHyaluronic Acid
Irritancy Medium Medium Low Low
Drying alcohol————
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Product summary

Judging from the ingredient list, "Clinicians Complex - C-Plus Antioxidant Cream" works well for improving skin hydration The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (cyclomethicone and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide 1, cholesterol, cyclomethicone, glycosphingolipids and sphingolipids) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This product also contains Vitamin C (Ascorbic Acid) 5.10% - 6.20% It can be helpful in stimulating collagen production, neutralizing free radicals in skin and improving pigmentation marks. We recommend to use up this product quickly after opening: Ascorbic Acid degrades fast when it gets in contact with air and light. The moment the product turns orange, it is a sign that a significant share of the vitamin C in it is no longer effective.
  • This moisturizer includes a form of Retinoids (vitamin A) - retinyl palmitate 0.20% - 0.35%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
  • As a plus, this moisturizer also contains Ceramides (ceramide 1 0.45% - 0.65%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: petrolatum

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 70.00$ up to 75.00$ in the United States and for 98.00CA$ in Canada.

For a detailed price comparison: click here.

Clinicians Complex C-Plus Antioxidant Cream
Clinicians ComplexC-Plus Antioxidant Cream

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