BioPrime REGENERATIVE SERUM

BioPrime REGENERATIVE SERUM

Efficacy75/100IrritancyMedium

Works for

Evens skin tone
Retinyl palmitate, Ascorbic acid
May help
What the product description says
“Tightens loose skin, improves elasticity, skin density, and firmness, while reducing fine lines and wrinkles, reducing photodamage and hyperpigmentation, while increasing keratinocyte proliferation [ 2 ]”
Source: BioPrime Supplements

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: retinyl palmitate.

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~1.9–2.8%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~1.4–2.1%
Anti-aging
Retinyl palmitate, Copper tripeptide-1 + 2 more
May help
What the product description says
“This synergistic formula offers the most potent healing and repair benefits of STABLE BPC-157 with the anti-aging and regenerative properties of GHK-Cu.”
Source: BioPrime Supplements

This product contains copper tripeptide-1, retinyl palmitate. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~1.9–2.8%
Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.2–0.75%
Aloe barbadensis leaf juiceEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~5–7.5%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~1.4–2.1%

Can it cause trouble?

Irritancy
1 strong irritant: Retinyl palmitate
Medium risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~1.9–2.8%est.
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~1.4–2.1%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~23–34%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~2.7–4.1%est.
EdtaHelp to stabilize the product formulationMedium~0.5–1%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.9–1.3%est.
Sorbic acidA preservativeMedium~0.3–0.6%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Aloe barbadensis leaf juice~23–34%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialAnti-inflammatoryReduces rednessReduces irritationAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Carbomer~8.8–13.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Aloe barbadensis leaf juice~5–7.5%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialReduces irritationReduces rednessAnti-inflammatoryAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Aloe barbadensis leaf polysaccharides~3.8–5.7%
Formula
Tocopheryl acetate~2.7–4.1%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Retinyl palmitate~1.9–2.8%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-blemishAnti-agingExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Ascorbic acid~1.4–2.1%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Edta~0.5–1%
Irritant · medium
Irritation risk
Medium

Help to stabilize the product formulation

More about Edta
Caprylyl glycol~0.9–1.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Phenoxyethanol~0.35–0.85%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sorbic acid~0.3–0.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Copper tripeptide-1~0.2–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1
98%+ pure stable bpc-157 (body protection compound) 10mg
Not recognized
Ingredient list view

Aloe barbadensis leaf juice, Carbomer, Aloe barbadensis leaf juice, Aloe barbadensis leaf polysaccharides, Tocopheryl acetate, Retinyl palmitate, Ascorbic acid, Edta, Caprylyl glycol, Phenoxyethanol, Sorbic acid, Copper tripeptide-1, Unknown

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
BioPrimeREGENERATIVE SERUMYOUR PRODUCTGlow Jar8% AM Vitamin C SerumPaula's choiceActive Serum Intensive Vitamin C and E + Ferulic AcidDIMEHyper Glow Serum
Match—75%75%74%
Price—$41.38—$32.00
Shared key ingredients—1 of 31 of 31 of 3
Key difference—Salicylic AcidFerulic AcidFerulic Acid
Irritancy Medium Low Low Low
Drying alcohol————
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Product summary

"BioPrime - REGENERATIVE SERUM" could be helpful for: Anti-aging and Evens skin tone, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (1.20% - 1.90%) it cannot have a noticeable benefit for the skin.
  • This product includes a form of Retinoids (vitamin A) - retinyl palmitate 1.50% - 2.20%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
  • Peptides (copper tripeptide-1 0.15% - 0.60%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

BioPrime REGENERATIVE SERUM
BioPrimeREGENERATIVE SERUM

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.