PRODUCT REVIEW
BeautyBio The Nightly Moduline Peptide Filling Sphere Serum
Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Evens skin tone
- Anti-blemish
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Can it cause trouble?
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What can the product work for?
Works for
Anti-aging
What does the product description say?
The perfect follow-on treatment from your GloPRO microneedling routine, The Nightly is an intense and potent serum boosted with deep-release retinol to stimulate cellular turnover and restore a youthful glow, moduline peptides to firm and smooth, and finally, hyaluronic acid filling spheres to draw in moisture to the deepest layers of the skin for plump skin and long-lasting hydration, The Nightly helps to get your skins volume-building engines back into high gear.
hydroxypinacolone retinoate
0.15% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
tetrahexyldecyl ascorbate
0.4% -
0.6%
Irritation risk:
Concentration: Insufficient!
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
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Moisturizing
What does the product description say?
The perfect follow-on treatment from your GloPRO microneedling routine, The Nightly is an intense and potent serum boosted with deep-release retinol to stimulate cellular turnover and restore a youthful glow, moduline peptides to firm and smooth, and finally, hyaluronic acid filling spheres to draw in moisture to the deepest layers of the skin for plump skin and long-lasting hydration, The Nightly helps to get your skins volume-building engines back into high gear.
glycerin
4% -
4.9%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
caprylic/capric triglyceride
1.5% -
1.9%
Irritation risk:
Concentration: Effectiveness: HIGH
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
sodium hyaluronate
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
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Anti-blemish
hydroxypinacolone retinoate
0.15% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
allantoin
0.3% -
0.5%
Irritation risk:
Concentration: Insufficient!
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Evens skin tone
hydroxypinacolone retinoate
0.15% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
tetrahexyldecyl ascorbate
0.4% -
0.6%
Irritation risk:
Concentration: Insufficient!
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 1
Potential irritants
hydroxypinacolone retinoate
0.15% -
0.3%
Irritation risk:
Works for:
Evens skin tone,
Anti-blemish,
Anti-aging,
Exfoliation
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
commiphora mukul resin extract
0.2% -
0.4%
Irritation risk:
Works for:
Anti-oxidation,
Anti-inflammatory
A plant extract might be helpful in neutralizing free radicals and reducing inflammation in skin
Show more
Comodogenic ingredients
ethylhexyl palmitate
6.1% -
7.5%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
An emollient that helps soften the skin and create a nice product texture
User reviews (0)
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Ingredients & concentrations
All ingredients
Key Actives
allantoin
0.3% -
0.5%
Irritation risk:
Works for:
Moisturizing,
Anti-inflammatory,
Anti-blemish,
Reduces irritation,
Reduces redness,
Exfoliation
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
tocopherol
0.35% -
0.6%
Irritation risk:
Works for:
Anti-oxidation,
Anti-inflammatory,
Moisturizing,
Anti-aging
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
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Potential irritants
hydroxypinacolone retinoate
0.15% -
0.3%
Irritation risk:
Works for:
Evens skin tone,
Anti-blemish,
Anti-aging,
Exfoliation
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
commiphora mukul resin extract
0.2% -
0.4%
Irritation risk:
Works for:
Anti-oxidation,
Anti-inflammatory
A plant extract might be helpful in neutralizing free radicals and reducing inflammation in skin
Show more
Comodogenic ingredients
ethylhexyl palmitate
6.1% -
7.5%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
An emollient that helps soften the skin and create a nice product texture
All ingredients
ethylhexyl palmitate
6.1% -
7.5%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
An emollient that helps soften the skin and create a nice product texture
glycerin
4% -
4.9%
Irritation risk:
Works for:
Moisturizing
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Show more
Ingredient list view
Water, Ethylhexyl palmitate, Glycerin, Peg-40 hydrogenated castor oil, Carbomer, Dimethyl isosorbide, Phenoxyethanol, Caprylic/capric triglyceride, Leuconostoc/radish root ferment filtrate, Aminomethyl propanol, Panthenol, Chlorphenesin, Benzoic acid, Butylene glycol, Bisabolol, Leontopodium alpinum meristem cell culture, Tetrahexyldecyl ascorbate, Tocopherol, Allantoin, Hydroxypinacolone retinoate, Disodium edta, Trihydroxystearin, Sorbic acid, Commiphora mukul resin extract, Sodium hyaluronate, Ci 77891, Titanium dioxide, Silica, Citric acid, Mica, Xanthan gum, Amorphophallus konjac root powder, Palmitoyl tripeptide-28
Sources
- Glycerol and the skin: holistic approach to its origin and functions
- Amended Safety Assessment of PEGylated Oils as Used in Cosmetics
- Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation
- Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage
- Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacy
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Profile of wound healing process induced by allantoin
- Antiaging effects of retinoid hydroxypinacolone retinoate on skin models. (2018). Journal of the American Academy of Dermatology, 79(3), AB44. doi:10.1016/j.jaad.2018.05.215
- Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres
- Pharmacology and Phytochemistry of Oleo-Gum Resin of Commiphora wightii (Guggulu)
- Hyaluronic acid: A key molecule in skin aging