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ADVANCED CLINICALS Hyaluronic Acid Cream
ADVANCED CLINICALS

ADVANCED CLINICALS Hyaluronic Acid Cream

Efficacy100/100IrritancyMedium
See all ingredients

Works for

Moisturizing
Paraffinum liquidum, Panthenol + 16 more
Works well
What the product description says
“Delivers long-lasting hydration and moisture.”
Source: Advanced Clinicals

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol, paraffinum liquidum

Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~4.5–5.5%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.5–0.75%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~6.3–7.8%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~2.8–3.4%
Cocos nucifera oilKey active· Emollient, OcclusiveEffect: HighAn emollient. Found to be as effective as a moisturizer for dry skin as mineral oil. Could be comedogenic~2.4–2.9%
Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~1.7–2.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.5–1.9%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~1.1–1.3%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.75–1.15%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.6–0.85%
Limnanthes alba seed oilKey active· EmollientEffect: HighThis oil's cmposition is closest to rapeseed oil. It is a very stable oil and serves as an emoillient~0.5–0.75%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.5–0.75%
Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.45–0.65%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.9–2.4%
Aloe barbadensis leaf juice powderEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.5–0.75%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.35–0.6%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.25%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~1.3–1.6%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~1.1–1.3%est.
Aloe barbadensis leaf juice powderTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.5–0.75%est.
GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.35–0.6%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.2–0.4%est.
EthylhexylglycerinA preservativeMedium~0.2–0.35%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.15–0.3%est.
Comedogenic
7 ingredients rated 2 or more on the 0–5 pore-clogging scale
7 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cocos nucifera oilAn emollient. Found to be as effective as a moisturizer for dry skin as mineral oil. Could be comedogenic3/5~2.4–2.9%est.
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~1.7–2.1%est.
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.75–1.15%est.
Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.45–0.65%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~6.3–7.8%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~2.8–3.4%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~1.3–1.6%est.
Alternatives
The closest match we found
Hyaluronic Acid Face & Body Cream Moisturizer
Elastalift Hyaluronic Acid Face & Body Cream Moisturizer
Closest match55% match
$15.99
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Cetearyl alcohol~6.3–7.8%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Paraffinum liquidum~4.5–5.5%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Glyceryl stearate se~2.8–3.4%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Cocos nucifera oil~2.4–2.9%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient. Found to be as effective as a moisturizer for dry skin as mineral oil. Could be comedogenic

More about Cocos nucifera oil
Butylene glycol~1.9–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Isopropyl myristate~1.7–2.1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Glycerin~1.5–1.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Ceteareth-20~1.3–1.6%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
Caprylic/capric triglyceride~1.1–1.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Butyrospermum parkii butter~0.75–1.15%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Sodium hyaluronate~0.6–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Aloe barbadensis leaf juice powder~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice powder
Panthenol~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Squalane~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Limnanthes alba seed oil~0.5–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

This oil's cmposition is closest to rapeseed oil. It is a very stable oil and serves as an emoillient

More about Limnanthes alba seed oil
Chondrus crispus extract~0.45–0.65%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract
Gluconolactone~0.35–0.6%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
ExfoliationAnti-agingEvens skin toneMoisturizingAnti-oxidationAnti-blemish

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone
Phenoxyethanol~0.3–0.6%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Tocopheryl acetate~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Tocopherol~0.25–0.45%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Caprylyl glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Acrylates/c10-30 alkyl acrylate crosspolymer~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Ethylhexylglycerin~0.2–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Hexylene glycol~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Parfum~0.15–0.25%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Tetrasodium glutamate diacetate~0.1–0.2%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Sodium hydroxide~0.1–0.2%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ingredient list view

Water, Cetearyl alcohol, Paraffinum liquidum, Glyceryl stearate se, Cocos nucifera oil, Butylene glycol, Isopropyl myristate, Glycerin, Ceteareth-20, Caprylic/capric triglyceride, Butyrospermum parkii butter, Sodium hyaluronate, Aloe barbadensis leaf juice powder, Panthenol, Squalane, Limnanthes alba seed oil, Chondrus crispus extract, Gluconolactone, Phenoxyethanol, Tocopheryl acetate, Tocopherol, Caprylyl glycol, Acrylates/c10-30 alkyl acrylate crosspolymer, Ethylhexylglycerin, Hexylene glycol, Parfum, Tetrasodium glutamate diacetate, Sodium hydroxide, Sodium benzoate

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Advanced Clinicals
$4.99
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Amazon USPrice as of 11/14 09:20 GMT
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ADVANCED CLINICALSHyaluronic Acid CreamYOUR PRODUCTElastaliftHyaluronic Acid Face & Body Cream MoisturizerCicaBiafineAnti-Irritations Moisturising CreamNeosporinEczema Essentials Daily Moisturizing Cream
Match—55%50%48%
Price$4.99$15.99+$11.00$15.17+$10.18—
Shared key ingredients—11 of 134 of 135 of 13
Key difference—Ceramide 2PetrolatumCeramide Np
Irritancy Medium Medium Low Low
Drying alcohol————
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Product summary

"ADVANCED CLINICALS - Hyaluronic Acid Cream" is effective for: Moisturizing

Ingredient callouts

  • Ceramides (ceramide 2 0.25% - 0.50%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • Humectants (sodium hyaluronate 0.50% - 0.70% and glycerin 1.80% - 2.20%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails at around 15.97$ in the United States, for 59.90A$ in Australia and for 28.89£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.

  1. 1
    A review on the extensive skin benefits of mineral oilncbi.nlm.nih.gov
  2. 2
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  3. 3
    Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
  4. 4
    Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
  5. 5
    Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
  6. 6
    Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
ADVANCED CLINICALS Hyaluronic Acid Cream
ADVANCED CLINICALSHyaluronic Acid Cream
Buy at Advanced Clinicals$4.99$16.99as of 11/14 09:20 GMT

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Buy at Advanced Clinicals$4.99$16.99as of 11/14 09:20 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.