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ZYMOGEN Centella Multi Balm
ZYMOGEN

ZYMOGEN Centella Multi Balm

Efficacy37/100IrritancyHigh
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Works for

1 of 2 advertised claims delivered

Moisturizing
Squalane, Ubiquinone + 12 more
Good evidence
What the product description says
“Can be used to moisturize dry skin before applying foundation, as an eye shadow base for long-lasting wear, and to moisturize chapped lips and cuticles.”
Source: Yesstyle

This product can help soften the skin and reduce its moisture loss with emollients and occlusives: beeswax, butyrospermum parkii butter.

Keep in mind that this product does not contain effective ingredients to attract water to the upper layer of the skin. This is why an additional product with humectants like glycerin or hyaluronic acid can be helpful (apply it before this product for the best results).

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1–1.5%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.2–0.7%
Rosa canina seed oilKey activeEffect: HighA plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishes~0.5–1.1%
Asiatic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.6%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.55%
BeeswaxKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~5.4–8.1%
Borago officinalis seed oilKey active· EmollientEffect: HighA plant oil that is effective in reducing irritation in skin, restore the barrier function and support its hydration~0.45–1.05%
Juglans regia seed oilKey activeEffect: HighHelps to soften the upper layer of the skin~0.35–0.85%
Madecassic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.45%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~3.8–5.8%
Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~1.7–2.5%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~22–33%
Macadamia ternifolia seed oilKey active· EmollientEffect: MediumPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients~0.35–0.85%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.1–0.35%
Exfoliation
No ingredient credited for this claim
No evidence
What the product description says
“Enriched with the highly moisturizing powers of cult favorite ingredient cica extract, this balm helps hydrate skin, remove dead skin cells and nourish skin!”
Source: Yesstyle

This product does not contain effective exfoliating ingredients. It might be able to deliver physical exfoliation, that is scrub off some of the dead cells on the surface of the skin. We do not recommend physical exfoliation, because it is not uniform (some bits of skin can get exfoliated too much while others not at all). It can also traumatize the skin and aggrevate acne and other skin conditions.

Anti-oxidation
Not advertised by the brand · Ubiquinone, Asiaticoside + 5 more
Strong evidence

This product contains antioxidants (asiaticoside, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - centella asiatica extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.2–0.7%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.55%
Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~1.7–2.5%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~3.8–5.8%
Tocopheryl acetateEffect: LowA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~1–1.5%
Borago officinalis seed oilEffect: LowA plant oil that is effective in reducing irritation in skin, restore the barrier function and support its hydration~0.45–1.05%
Rosa canina seed oilEffect: LowA plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishes~0.5–1.1%
Anti-aging
Not advertised by the brand · Asiaticoside, Centella asiatica extract + 2 more
Moderate evidence

This product contains asiaticoside, centella asiatica extract. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.55%
Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~1.7–2.5%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~3.8–5.8%
UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.2–0.7%

Can it cause trouble?

Irritancy
5 strong irritants: Sorbitan sesquioleate, Lavandula angustifolia oil + 3 more — patch-test recommended
High risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Sorbitan sesquioleateUsed to help oil and water mix together. Can be irritatingHigh~1.4–2%est.
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.55–1.3%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.2%est.
GeraniolA fragrance. Can be irritatingHigh~0.05–0.15%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.05–0.1%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~1.7–2.5%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~1–1.5%est.
Rosa canina seed oilA plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishesMedium~0.5–1.1%est.
Juglans regia seed oilHelps to soften the upper layer of the skinMedium~0.35–0.85%est.
Macadamia ternifolia seed oilPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredientsMedium~0.35–0.85%est.
AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.15–0.55%est.
Asiatic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.15–0.6%est.
Madecassic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.1–0.45%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~3.8–5.8%est.
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Alternatives
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Cicaluronic Moisturizer
Mizon Cicaluronic Moisturizer
Higher efficacy · 75/10053% match
$14.56
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Ingredients

Filter by role to see what each ingredient is doing.

Helianthus annuus seed oil~22–33%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Beeswax~5.4–8.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Beeswax
Microcrystalline wax~4.5–6.8%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Microcrystalline wax
Butyrospermum parkii butter~3.8–5.8%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Bacillus~2.5–3.8%
Formula
Irritation risk
Low
More about Bacillus
Centella asiatica extract~1.7–2.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Reduces irritationReduces rednessMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Ferment filtrate
Not recognized
Sorbitan sesquioleate~1.4–2%
Irritant · high
Irritation risk
High
Works for
Cleansing

Used to help oil and water mix together. Can be irritating

More about Sorbitan sesquioleate
Tocopheryl acetate~1–1.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Squalane~1–1.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Lavandula angustifolia oil~0.55–1.3%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Rosa canina seed oil~0.5–1.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-inflammatoryAnti-oxidation

A plant oil that helps soften the upper layer of the skin. It might have anti-oxidant properties. Might help reduce inflammation in skin and help against blemishes

More about Rosa canina seed oil
Borago officinalis seed oil~0.45–1.05%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationAnti-oxidation

A plant oil that is effective in reducing irritation in skin, restore the barrier function and support its hydration

More about Borago officinalis seed oil
Juglans regia seed oil~0.35–0.85%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps to soften the upper layer of the skin

More about Juglans regia seed oil
Macadamia ternifolia seed oil~0.35–0.85%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

More about Macadamia ternifolia seed oil
Ubiquinone~0.2–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone
Asiaticoside~0.15–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationReduces irritationAnti-aging

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside
Asiatic acid~0.15–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritationAnti-inflammatory

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiatic acid
Madecassic acid~0.1–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Madecassic acid
Butylene glycol~0.1–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Phenoxyethanol~0.1–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Linalool~0.05–0.2%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Geraniol~0.05–0.15%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Limonene~0.05–0.1%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Ingredient list view

Helianthus annuus seed oil, Beeswax, Microcrystalline wax, Butyrospermum parkii butter, Bacillus, Centella asiatica extract, Unknown, Sorbitan sesquioleate, Tocopheryl acetate, Squalane, Lavandula angustifolia oil, Rosa canina seed oil, Borago officinalis seed oil, Juglans regia seed oil, Macadamia ternifolia seed oil, Ubiquinone, Asiaticoside, Asiatic acid, Madecassic acid, Butylene glycol, Phenoxyethanol, Linalool, Geraniol, Limonene

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ZYMOGENCentella Multi BalmYOUR PRODUCTharuharu USCentella Phyto & 5 Peptide Concentrate CreamMizonCicaluronic MoisturizerMaya ChiaThe Advanced Response Complex | Rapid Regenerating, Firming Face & Neck Moisture Cream
Match—53%53%52%
Price$14.50$10.18−$4.32$14.56$110.00+$95.50
Shared key ingredients—7 of 126 of 126 of 12
Key difference—Copper Tripeptide-1MadecassosideHexapeptide-11
Irritancy High Medium Medium Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 22 studies and safety reviews.

  1. 1
    Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
  2. 2
    Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
  3. 3
    Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
  4. 4
    Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countriesonlinelibrary.wiley.com
  5. 5
    Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Modelmdpi.com
  6. 6
    Centella asiatica in cosmetologyncbi.nlm.nih.gov
ZYMOGEN Centella Multi Balm
ZYMOGENCentella Multi Balm
Buy at Yesstyle$14.50Amazon

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Buy at Yesstyle$14.50Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.