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Swiss Clinic Grade Up Retinol+ 0.3%
Swiss Clinic

Swiss Clinic Grade Up Retinol+ 0.3%

Efficacy75/100IrritancyMedium
See all ingredients

Works for

Moisturizing
Helianthus annuus hybrid oil, Caprylic/capric triglyceride + 5 more
Works
What the product description says
“Repairs, moisturises and strengthens skin”
Source: Currentbody

This product can help soften the skin and reduce its moisture loss with emollients and occlusives: caprylic/capric triglyceride, squalane.

Keep in mind that this product does not contain effective ingredients to attract water to the upper layer of the skin. This is why an additional product with humectants like glycerin or hyaluronic acid can be helpful (apply it before this product for the best results).

Helianthus annuus hybrid oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin~22–34%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~9.5–14.2%
Hydrogenated ethylhexyl olivateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~5–7.5%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~4–6%
Hydrogenated olive oil unsaponifiablesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~2.8–4.2%
Canola oilKey active· EmollientEffect: MediumA plant oil that can help soften the upper layer of the skin~1.7–2.5%
TocopherolEffect: LowPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.6%
Anti-aging
Retinyl palmitate, Tocopherol
May help
What the product description says
“Softens fine lines and evens out pigmentation”
Source: Currentbody

This product contains retinyl palmitate. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.35–0.8%
TocopherolEffect: LowPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.6%
Evens skin tone
Retinyl palmitate
May help
What the product description says
“Softens fine lines and evens out pigmentation”
Source: Currentbody

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: retinyl palmitate.

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.35–0.8%
Anti-oxidation
Side benefit · Tocopherol
Works well

This product contains antioxidants (tocopherol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

TocopherolKey activeEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.6%

Can it cause trouble?

Irritancy
1 strong irritant: Retinyl palmitate
Medium risk
We flagged 3 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.35–0.8%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~9.5–14.2%est.
Canola oilA plant oil that can help soften the upper layer of the skinMedium~1.7–2.5%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

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Helianthus annuus hybrid oil~22–34%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Helianthus annuus hybrid oil
Caprylic/capric triglyceride~9.5–14.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Hydrogenated ethylhexyl olivate~5–7.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Hydrogenated ethylhexyl olivate
Squalane~4–6%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Hydrogenated olive oil unsaponifiables~2.8–4.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Help soften the upper layer of the skin

More about Hydrogenated olive oil unsaponifiables
Tocopherol~1.1–1.6%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryMoisturizingAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Canola oil~1.7–2.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that can help soften the upper layer of the skin

More about Canola oil
Retinyl palmitate~0.35–0.8%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-blemishAnti-agingExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Ingredient list view

Helianthus annuus hybrid oil, Caprylic/capric triglyceride, Hydrogenated ethylhexyl olivate, Squalane, Hydrogenated olive oil unsaponifiables, Tocopherol, Canola oil, Retinyl palmitate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Swiss ClinicGrade Up Retinol+ 0.3%YOUR PRODUCTSKKN by KimOil DropsMeVitamin C with Squalane BoosterEdible BeautyBeauty Reset Drops
Match—38%38%36%
Price——$16.09$29.00
Shared key ingredients—2 of 53 of 52 of 5
Key difference—Tetrahexyldecyl AscorbateAscorbyl TetraisopalmitateBakuchiol
Irritancy Medium Low Low Low
Drying alcohol————
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Product summary

"Swiss Clinic - Grade Up Retinol+ 0.3%" could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • this product includes a form of Retinoids (vitamin A) - retinyl palmitate 0.35% - 0.80%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.

Price

The product retails for 33.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 3 studies and safety reviews.

  1. 1
    Vitamin E in dermatologyncbi.nlm.nih.gov
  2. 2
    Vitamin E and Skin Healthlpi.oregonstate.edu
  3. 3
    Canola Oilsciencedirect.com
Swiss Clinic Grade Up Retinol+ 0.3%
Swiss ClinicGrade Up Retinol+ 0.3%
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