SkinMedica TNS Advanced+ Serum
Works for
Anti-agingHuman fibroblast conditioned media, Lactococcus ferment lysateWorks well
“SkinMedica's TNS Advanced+ Serum is a skin rejuvenating formula that visibly improves the appearance of coarse wrinkles, fine lines and sagging skin.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains human fibroblast conditioned media.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
MoisturizingShea butter ethyl esters, Glycerin + 9 moreWorks
“Next-generation growth factor blend supports healthy skin functions and an innovative peptide complex nourishes your skin.”
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin, saccharide isomerate.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
Evens skin toneNo ingredient credited for this claimNot delivered
“Evens the appearance of skin tone and texture”
Effective ingredients missing or their concentration is too low
Can it cause trouble?
Irritancy10 flagged ingredientsLow risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
1 of 1 community members would buy it again.
Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Pentylene glycol~5.7–7%
- Irritation risk
- Medium
Used to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolHuman fibroblast conditioned media~4.6–5.6%
- Irritation risk
- Low
A cocktail of amino acids that can stimulate skin cell growth and renewal having an anti-aging effect
More about Human fibroblast conditioned mediaGlycereth-7 triacetate~3.3–4.1%
- Irritation risk
- Low
Shea butter ethyl esters~2.7–3.3%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Shea butter ethyl estersGlycerin~2.2–2.7%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinEthoxydiglycol~1.6–2%
Lactococcus ferment lysate~1.4–1.8%
- Irritation risk
- Low
Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin
More about Lactococcus ferment lysateWhey protein~1.3–1.6%
- Irritation risk
- Low
A protein derived from milk. In skincare products, might help to soften the upper layer of the skin
More about Whey proteinChlorella vulgaris extract~1.1–1.3%
- Irritation risk
- Medium
- Comedogenicity
- 3/5
A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties
More about Chlorella vulgaris extractSaccharide isomerate~0.9–1.1%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin
More about Saccharide isomerateDimer tripeptide-43~0.7–1.05%
- Irritation risk
- Low
Vitis vinifera flower cell extract~0.7–1.05%
- Irritation risk
- Low
Pyrus malus fruit extract~0.65–0.95%
- Irritation risk
- Medium
Can have some moisturizing properties due to its sugar content
More about Pyrus malus fruit extractHydroxyacetophenone~0.65–0.95%
Tocopheryl acetate~0.6–0.9%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetatePropanediol~0.5–0.8%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolXanthan gum~0.5–0.7%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumPolyacrylate crosspolymer-6~0.45–0.65%
- Irritation risk
- Low
Polyacrylate-13~0.4–0.6%
- Irritation risk
- Low
Used to create a thicker product consistency and stabilize the product formulation
More about Polyacrylate-13Polyisobutene~0.35–0.6%
Sclerotium gum~0.3–0.5%
- Irritation risk
- Low
Used to create gel-like formulas and stabilize emulsions
More about Sclerotium gumPeg-12 dimethicone~0.25–0.45%
- Irritation risk
- Low
Helps soften the upper layer of the skin and create a nice product texture
More about Peg-12 dimethiconeLecithin~0.25–0.5%
- Irritation risk
- Low
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
More about LecithinPullulan~0.2–0.35%
- Irritation risk
- High
Creates a thin drying film on the skin resulting in a short-term tightening effect
More about PullulanButylene glycol~0.15–0.3%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolSodium citrate~0.1–0.2%
- Irritation risk
- Medium
Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products
More about Sodium citratePolysorbate 20~0.15–0.25%
Aminomethyl propanol~0.1–0.15%
Disodium edta~0.05–0.1%
Phenoxyethanol~0.05–0.1%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolEthylhexylglycerin~0.01–0.05%
Ingredient list view
Water, Pentylene glycol, Human fibroblast conditioned media, Glycereth-7 triacetate, Shea butter ethyl esters, Glycerin, Ethoxydiglycol, Lactococcus ferment lysate, Whey protein, Chlorella vulgaris extract, Saccharide isomerate, Dimer tripeptide-43, Vitis vinifera flower cell extract, Pyrus malus fruit extract, Hydroxyacetophenone, Tocopheryl acetate, Propanediol, Xanthan gum, Polyacrylate crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium gum, Peg-12 dimethicone, Lecithin, Pullulan, Butylene glycol, Sodium citrate, Polysorbate 20, Aminomethyl propanol, Disodium edta, Phenoxyethanol, Ethylhexylglycerin
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| SkinMedicaTNS Advanced+ SerumYOUR PRODUCT | Medical Beauty ResearchTissue Activator Serum | REMEDY SCIENCEREMEDY Multi-Depth Moisture Advanced Hydrating Serum | Geek GorgeousPower Peptides Serum | |
|---|---|---|---|---|
| Match | — | 33% | 33% | 33% |
| Price | $295.00 | $231.00−$64.00 | $20.00−$275.00 | $16.57−$278.43 |
| Shared key ingredients | — | 2 of 5 | 2 of 5 | 2 of 5 |
| Key difference | — | Tripeptide-1 | Palmitoyl Tripeptide-5 | Copper Palmitoyl Heptapeptide-14 |
| Irritancy | Low | Low | Low | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: RevivSerums Ultimate SerumDIBI Milano Lift Creator Collagen & Elastin Concentrate
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 3 studies and safety reviews.
- 1
- 2TOPICAL COMPOSITIONS CONTAINING WHEY PROTEINS patentimages.storage.googleapis.com
- 3
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