
“Perricone MD's Blemish Relief Targeted Spot Treatment tackles existing breakouts while minimising the formation of future blemishes for a visibly clearer, calmer complexion.”
This product can help reduce breakouts and clogged pores because it contains the following ingredient: salicylic acid. This ingredient is used for treating acne and can have a noticeable effect.
“They also provide gentle yet effective exfoliation for smoother, more even- looking skin.”
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: salicylic acid.
“Nourishing & soothing, it is an ideal way to counteract the irritating effects of anti- blemish ingredients.”
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": citrulline, glycerin.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol, urea

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Filter by role to see what each ingredient is doing.
Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties
More about Sd alcohol 40-bActs as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolA plant extract that can help calm down inflammation in skin. Can, however, itself be irritating
More about Hamamelis virginiana waterOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
More about Salicylic acidCan help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion
More about SucroseAn amino-acid that helps attract water to the upper layer of the skin
More about CitrullineUsed to thicken product formulations and create gel-like textures
More about HydroxyethylcelluloseNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
More about UreaHelps attract water to the upper layer of the skin and can help improve skin barrier function
More about PanthenolAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)
More about Lactic acidAn essential oil that can be irritating. Has some anti-bacterial properties
More about Melaleuca alternifolia leaf oilHelps stabilize the product formulation
More about Tetrasodium glutamate diacetateCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties
More about AlcoholWater, Sd alcohol 40-b, Propanediol, Hamamelis virginiana water, Glycerin, Salicylic acid, Sucrose, Citrulline, Hydroxyethylcellulose, Urea, Panthenol, Lactic acid, Melaleuca alternifolia leaf oil, Sodium hydroxide, Tetrasodium glutamate diacetate, Succinic acid, Alcohol, Polysorbate 20
Retailers ranked by price — lowest first.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Perricone MDTreatments Blemish Relief Targeted Spot TreatmentYOUR PRODUCT | Dr Dennis GrossAlpha Beta Intense Glow Pads for Face | MuradRapid Relief Acne Spot Treatment | B. KaminsLactic-10 | |
|---|---|---|---|---|
| Match | — | 83% | 82% | 81% |
| Price | — | $39.00 | $17.00 | — |
| Shared key ingredients | — | 4 of 7 | 3 of 7 | 4 of 7 |
| Key difference | — | Retinyl Palmitate | Oatmeal Extract | Zinc Pca |
| Irritancy | High | Medium | Medium | Low |
| Drying alcohol | Contains drying alcohol | — | Contains drying alcohol | — |
| View product | Shop | Shop | Shop |
More alternatives: Beauty Drops AHA 30% + BHA 2% PeelingFenty Skin Blemish Defeat'r BHA Spot-Targeting Gel
"Perricone MD - Treatments Blemish Relief Targeted Spot Treatment" is effective for: Anti-blemish, Anti-inflammatory, Exfoliation and Moisturizing
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
The product retails for 21.66€ in Germany, from 18.90£ up to 523.00£ in the United Kingdom and for 35.00CA$ in Canada.
For a detailed price comparison: click here.
Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.
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