Works for
MoisturizingSqualane, Caprylic/capric triglyceride + 6 moreWorks
“CAIL) is a plumping nighttime gel engineered to visibly improve volume and hydration as the skin ages.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
aphanizomenon flos-aquae extract, biosaccharide gum-1.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.
Anti-agingNo ingredient credited for this claimNot delivered
“Repairs the look of aging skin by minimizing visible fine lines and wrinkles and promoting visible firmness.”
This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.
This ingredient aphanizomenon flos-aquae extract might be able to help neutralize free radicals in skin and help it fight off some of the sun damage.
Evens skin toneNo ingredient credited for this claimNot delivered
“Skin tone looks more even and radiant.”
Effective ingredients missing or their concentration is too low
Anti-oxidationSide benefit · Aphanizomenon flos-aquae extract, Hydroxymethoxyphenyl propylmethylmethoxybenzofuran + 2 moreMay help
This product contains antioxidants (aphanizomenon flos-aquae extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Can it cause trouble?
Irritancy1 strong irritant: Hydroxymethoxyphenyl propylmethylmethoxybenzofuranMedium risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
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Ingredients
Filter by role to see what each ingredient is doing.
Squalane~25–37%
- Irritation risk
- Low
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneCaprylic/capric triglyceride~7.2–10.7%
- Irritation risk
- Medium
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
More about Caprylic/capric triglycerideGlycerin~4.4–6.6%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinWater~3.1–4.7%
Hydrogenated starch hydrolysate~2.1–3.1%
- Irritation risk
- Low
Helps to attract water to the upper layer of the skin. Can add sweet taste to lip products
More about Hydrogenated starch hydrolysateSucrose laurate~1.9–2.8%
- Irritation risk
- Low
Helps oil and water mix together. Can be used as a cleansing agent
More about Sucrose lauratePropanediol~1.3–2%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolSucrose stearate~1.2–1.7%
Copper tripeptide-1 palmitamide~0.8–1.25%
- Irritation risk
- Low
Glycolipids~0.5–1.15%
- Irritation risk
- Low
Hydroxymethoxyphenyl propylmethylmethoxybenzofuran~0.5–1.1%
- Irritation risk
- High
It is a derivative of isoeugenol, an aromatic compound in clove essential oil. It is sold to cosmetic companies under the name Sym3D. The ingredient's manufacturer claims that it is able to plump lips and have an anti-aging effect. The evidence of effectiveness, however, is weak. The lab tests with skin models (not with real people) show that it, in theory, it can increase the number and size of fat cells underneath the skin and can work as an anti-oxidant. To impact the fat cells, the ingredient, however, needs to penetrate deep through the skin - and it is unlikely that it can do this. A clinical test with 44 female volunteers conducted by the manufacturer showed that twice daily application of this ingredient in 0.25% concentration on lips increased their volume by 6% in 28 days. It is unclear where the effect is coming from. It is possible that this visible effect appears because of the skin irritation
More about Hydroxymethoxyphenyl propylmethylmethoxybenzofuranVetiveria zizanoides root extract~0.35–0.85%
- Irritation risk
- Low
Aphanizomenon flos-aquae extract~0.3–0.75%
- Irritation risk
- Low
An extract from ablue-green algae. Can help attract water to the upper layer of the skin and might help to neutralize free radicals
More about Aphanizomenon flos-aquae extractHydroxymethoxyphenyl decanone~0.2–0.75%
- Irritation risk
- Low
An anti-oxidant. Is also called 6-paradol. It might be able to neutralize free radicals in skin. The manufacturer claims that it is able to stimulate synthesis of hyaluronic acid in skin, but there is no evidence of effectiveness of this ingredient so far. The only evidence of efficacy for this ingredient so far come from small lab tests. This ingredient comes together with Caprylic/Capric Triglyceride as part of the complex called SymDecanox HA produced by a cosmetic ingredient supplier Symrise.
More about Hydroxymethoxyphenyl decanoneBisabolol~0.15–0.6%
- Irritation risk
- Low
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
More about BisabololBiosaccharide gum-1~0.1–0.45%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
More about Biosaccharide gum-1Maltodextrin~0.1–0.4%
- Irritation risk
- Low
Used to stabilize the product formulation and can help absorb oil
More about MaltodextrinPotassium sorbate~0.1–0.3%
Sodium benzoate~0.05–0.2%
Chlorphenesin~0.05–0.2%
Phenoxyethanol~0.05–0.2%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolIngredient list view
Squalane, Caprylic/capric triglyceride, Glycerin, Water, Hydrogenated starch hydrolysate, Sucrose laurate, Propanediol, Sucrose stearate, Copper tripeptide-1 palmitamide, Glycolipids, Hydroxymethoxyphenyl propylmethylmethoxybenzofuran, Vetiveria zizanoides root extract, Aphanizomenon flos-aquae extract, Hydroxymethoxyphenyl decanone, Bisabolol, Biosaccharide gum-1, Maltodextrin, Potassium sorbate, Sodium benzoate, Chlorphenesin, Phenoxyethanol
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| NIODCopper Amino Isolate Lipid 1 %YOUR PRODUCT | Pacifica BeautyBerry Dewy Barrier Support Serum | Dieux SkinFirm Revival HydroRetinal Firming Serum | NeocutisBio Serum Firm | |
|---|---|---|---|---|
| Match | — | 44% | 39% | 39% |
| Price | $93.00 | $16.00−$77.00 | — | $281.77+$188.77 |
| Shared key ingredients | — | 3 of 6 | 4 of 6 | 3 of 6 |
| Key difference | — | Niacinamide | Retinal | Aminopropyl Ascorbyl Phosphate |
| Irritancy | Medium | Low | Medium | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: BalmLabs ClearBalm Serum HydratorKate Somerville Kx Active Concentrates Squalane + Hyaluronic Serum
Product summary
"NIOD - Copper Amino Isolate Lipid 1 %" could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- Humectants (biosaccharide gum-1 0.10% - 0.45%, aphanizomenon flos-aquae extract 0.30% - 0.75% and glycerin 4.40% - 6.60%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 93.00$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 6 studies and safety reviews.
- 1
- 2Safety assessment of hydrogenated starch hydrolysatesncbi.nlm.nih.gov
- 3
- 4
- 5Designing topical hyaluronic acid technology—Size does matteronlinelibrary.wiley.com
- 6
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