Naturopathica Argan & Peptide Wrinkle Repair Cream

Naturopathica Argan & Peptide Wrinkle Repair Cream

Efficacy87/100IrritancyHigh

Works for

Moisturizing
Palmitoyl tripeptide-38, Glycerin + 18 more
Works well
What the product description says
“A daily face moisturizer that improves the appearance of fine lines and wrinkles for a more youthful-looking complexion.”
Source: Dermstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, isomalt.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl tripeptide-38

Palmitoyl tripeptide-38HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–5.3%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~4.2–5.1%
C10-18 triglyceridesKey active· EmollientEffect: MediumHelps soften the skin and attract water to its upper layer. Helps create nice product texture~1.9–2.3%
Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~1–1.2%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.7–1.1%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.5–0.75%
Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.3–0.5%
IsomaltKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.3–0.6%
Lactobacillus fermentKey active· HumectantEffect: HighA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~0.25–0.5%
Plankton extractKey activeEffect: MediumCan help attract water to the upper layer of the skin~0.25–0.5%
Argania spinosa sprout cell extractKey activeEffect: HighPlant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals~0.2–0.4%
Cocoglycerides· EmollientEffect: LowHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin~2.9–3.6%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.6–2%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.45–0.7%
Moringa oleifera seed oil· EmollientEffect: LowA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid~0.3–0.55%
Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~0.3–0.55%
Tanacetum annuum flower oilEffect: LowAn essential oil that has anti-inflammatory properties but also contains irritating compounds~0.2–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.4%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.55%
Anti-aging
Palmitoyl tripeptide-38, Argania spinosa sprout cell extract + 1 more
May help
What the product description says
“A daily face moisturizer that improves the appearance of fine lines and wrinkles for a more youthful-looking complexion.”
Source: Dermstore

This product contains palmitoyl tripeptide-38. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl tripeptide-38Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Argania spinosa sprout cell extractEffect: LowPlant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals~0.2–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.4%
Anti-oxidation
Not advertised by the brand · Dimethylmethoxy chromanol, Lactobacillus ferment + 3 more
Works well

This product contains antioxidants (dimethylmethoxy chromanol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Dimethylmethoxy chromanolKey activeEffect: HighCan help neutralize free radicals in skin~0.25–0.5%
Lactobacillus fermentEffect: LowA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~0.25–0.5%
Argania spinosa sprout cell extractEffect: LowPlant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals~0.2–0.4%
Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.1–0.2%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.1–1.4%

Can it cause trouble?

Irritancy
9 strong irritants: Pelargonium graveolens leaf oil, Citrus aurantium amara flower extract + 7 more — patch-test recommended
High risk
We flagged 20 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
CocoglyceridesHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skinHigh~2.9–3.6%est.
Pelargonium graveolens leaf oilAn essential oil used as a fragrance. Can be irritatingHigh~0.25–0.5%est.
Anthemis nobilis flower extractA plant extract that one one hand, can contain compounds that can help calm down skin irritation, but, on the other hand, its other compounds (especially fragrant ones) can themselves be irritatingHigh~0.25–0.4%est.
Citrus aurantium amara flower extractUsed as a fragrance for its citrus smell. Can be irritatingHigh~0.25–0.45%est.
Tanacetum annuum flower oilAn essential oil that has anti-inflammatory properties but also contains irritating compoundsHigh~0.2–0.4%est.
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.15–0.3%est.
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.1–0.2%est.
CitronellolA fragrance. Can be irritatingHigh~0.15–0.25%est.
GeraniolA fragrance. Can be irritatingHigh~0.1–0.2%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.1–0.15%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.15%est.
Candelilla/jojoba/rice bran polyglyceryl-3 estersHelp oil and water mix togetherMedium~1.4–1.7%est.
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~1–1.2%est.
Sodium stearoyl lactylateHelps oil and water mix togetherMedium~0.5–0.75%est.
1,2-hexanediolA preservativeMedium~0.45–0.65%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.45–0.7%est.
Moringa oleifera seed oilA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acidMedium~0.3–0.55%est.
Plankton extractCan help attract water to the upper layer of the skinMedium~0.25–0.5%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.45%est.
Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~0.3–0.55%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Plankton extractCan help attract water to the upper layer of the skin3/5~0.25–0.5%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.5–0.75%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.3–5.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Squalane~4.2–5.1%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Cocoglycerides~2.9–3.6%
Irritant · high
Irritation risk
High
Works for
CleansingMoisturizing

Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin

More about Cocoglycerides
Methylheptyl isostearate~2.3–2.8%
Formula
C10-18 triglycerides~1.9–2.3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the skin and attract water to its upper layer. Helps create nice product texture

More about C10-18 triglycerides
Glyceryl stearate~1.6–2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Candelilla/jojoba/rice bran polyglyceryl-3 esters~1.4–1.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Help oil and water mix together

More about Candelilla/jojoba/rice bran polyglyceryl-3 esters
Tocopherol~1.1–1.4%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Jojoba esters~1–1.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Helianthus annuus seed oil~0.7–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Sclerotium gum~0.55–0.85%
Formula
Irritation risk
Low

Used to create gel-like formulas and stabilize emulsions

More about Sclerotium gum
Fructan~0.5–0.75%
Formula
Irritation risk
Low
More about Fructan
Sodium stearoyl lactylate~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl lactylate
Cetearyl alcohol~0.5–0.75%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
1,2-hexanediol~0.45–0.65%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Caprylyl glycol~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Behenyl olivate~0.4–0.6%
Formula
Isomalt~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Isomalt
Xanthan gum~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Hydrolyzed sodium hyaluronate~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate
Lactobacillus ferment~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatoryReduces irritation

A fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative

More about Lactobacillus ferment
Leontopodium alpinum meristem cell culture~0.25–0.45%
Formula
Moringa oleifera seed oil~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid

More about Moringa oleifera seed oil
Vaccinium vitis-idaea seed oil~0.3–0.55%
Formula
Hippophae rhamnoides seed oil~0.25–0.5%
Formula
Pelargonium graveolens leaf oil~0.25–0.5%
Irritant · high
Irritation risk
High

An essential oil used as a fragrance. Can be irritating

More about Pelargonium graveolens leaf oil
Dimethylmethoxy chromanol~0.25–0.5%
Key active
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin

More about Dimethylmethoxy chromanol
Lecithin~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Plankton extract~0.25–0.5%
Key activeComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Can help attract water to the upper layer of the skin

More about Plankton extract
Citric acid~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium phytate~0.25–0.5%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Hydroxypropyl cyclodextrin~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin
Helichrysum angustifolium flower extract~0.25–0.45%
Formula
Anthemis nobilis flower extract~0.25–0.4%
Irritant · high
Irritation risk
High
Works for
Reduces irritationAnti-inflammatory

A plant extract that one one hand, can contain compounds that can help calm down skin irritation, but, on the other hand, its other compounds (especially fragrant ones) can themselves be irritating

More about Anthemis nobilis flower extract
Citrus aurantium amara flower extract~0.25–0.45%
Irritant · high
Irritation risk
High

Used as a fragrance for its citrus smell. Can be irritating

More about Citrus aurantium amara flower extract
Isostearic acid~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a nice product texture

More about Isostearic acid
Lepidium sativum sprout extract~0.25–0.4%
Formula
Argania spinosa sprout cell extract~0.2–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-agingAnti-oxidation

Plant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals

More about Argania spinosa sprout cell extract
Tanacetum annuum flower oil~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryMoisturizing

An essential oil that has anti-inflammatory properties but also contains irritating compounds

More about Tanacetum annuum flower oil
Sodium benzoate~0.2–0.35%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Palmitoyl tripeptide-38~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-38
Alcohol~0.15–0.3%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Rosmarinus officinalis leaf extract~0.1–0.2%
Irritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Citronellol~0.15–0.25%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Geraniol~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Limonene~0.1–0.15%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Linalool~0.05–0.15%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Ingredient list view

Water, Glycerin, Squalane, Cocoglycerides, Methylheptyl isostearate, C10-18 triglycerides, Glyceryl stearate, Candelilla/jojoba/rice bran polyglyceryl-3 esters, Tocopherol, Jojoba esters, Helianthus annuus seed oil, Sclerotium gum, Fructan, Sodium stearoyl lactylate, Cetearyl alcohol, 1,2-hexanediol, Caprylyl glycol, Behenyl olivate, Isomalt, Xanthan gum, Hydrolyzed sodium hyaluronate, Lactobacillus ferment, Leontopodium alpinum meristem cell culture, Moringa oleifera seed oil, Vaccinium vitis-idaea seed oil, Hippophae rhamnoides seed oil, Pelargonium graveolens leaf oil, Dimethylmethoxy chromanol, Lecithin, Plankton extract, Citric acid, Sodium phytate, Hydroxypropyl cyclodextrin, Helichrysum angustifolium flower extract, Anthemis nobilis flower extract, Citrus aurantium amara flower extract, Isostearic acid, Lepidium sativum sprout extract, Argania spinosa sprout cell extract, Tanacetum annuum flower oil, Sodium benzoate, Palmitoyl tripeptide-38, Alcohol, Rosmarinus officinalis leaf extract, Citronellol, Geraniol, Limonene, Linalool

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Amazon USPrice as of 11/8 06:23 GMT
$100.00
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Dermstore1.7 fl. oz
$124.00 Out of stock
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NaturopathicaArgan & Peptide Wrinkle Repair CreamYOUR PRODUCTAlpha-H24 Hour Moisture Repair CreamPrimaThe Afterglow Deep Moisture Cream with Hyaluronic Acid + 500mg CBDMGC DermaBrightening Cream
Match—62%57%57%
Price$100.00——$27.31−$72.69
Shared key ingredients—6 of 116 of 114 of 11
Key difference—Lactic AcidButyrospermum Parkii ButterCbd
Irritancy High Medium High Medium
Drying alcohol Contains drying alcohol —— Contains drying alcohol
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Product summary

Judging from the ingredient list, "Naturopathica - Argan & Peptide Wrinkle Repair Cream" works well for improving skin hydration The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (glycerin, isomalt, lactobacillus ferment and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (hippophae rhamnoides oil, jojoba esters, squalane, c10-18 triglycerides and cetearyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We like that this moisturizer contains peptides (palmitoyl tripeptide-38 0.50% - 0.75%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 100.00$ up to 124.00$ in the United States and for 147.50CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

  1. 1
  2. 2
    Vitamin E in dermatologyncbi.nlm.nih.gov
  3. 3
    Vitamin E and Skin Healthlpi.oregonstate.edu
  4. 4
  5. 5
  6. 6
Naturopathica Argan & Peptide Wrinkle Repair Cream
NaturopathicaArgan & Peptide Wrinkle Repair Cream

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As an Amazon Associate, WIMJ earns from qualifying purchases.