Naturopathica Argan & Peptide Wrinkle Repair Cream

Naturopathica Argan & Peptide Wrinkle Repair Cream

Efficacy87/100IrritancyHigh
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Works for

2 of 2 advertised claims delivered

Moisturizing
18 ingredients credited for this claim
Strong support
What the product description says
“Argan & Peptide Wrinkle Repair Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, isomalt.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, hippophae rhamnoides oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl tripeptide-38

Lactobacillus fermentKey active· HumectantEffect: HighA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~1.6–1.9%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–5.3%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~4.2–5.1%
Hippophae rhamnoides oilKey active· EmollientEffect: HighA good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.~0.5–0.75%
Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~0.75–1.1%
Palmitoyl tripeptide-38HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
IsomaltKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.1–0.25%
Argania spinosa sprout cell extractKey activeEffect: HighPlant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals~0.45–0.7%
C10-18 triglyceridesKey active· EmollientEffect: MediumHelps soften the skin and attract water to its upper layer. Helps create nice product texture~1.9–2.3%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.3–0.5%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.35%
Cocoglycerides· EmollientEffect: LowHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin~2.9–3.6%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1–1.2%
Moringa oleifera seed oil· EmollientEffect: LowA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid~0.45–0.7%
Tanacetum annuum flower oilEffect: LowAn essential oil that has anti-inflammatory properties but also contains irritating compounds~0.25–0.45%
Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~0.25–0.45%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.6–0.85%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.5%
Anti-aging
3 ingredients credited for this claim
Moderate support
What the product description says
“Argan & Peptide Wrinkle Repair Cream”
From product name

This product contains palmitoyl tripeptide-38. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl tripeptide-38Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Argania spinosa sprout cell extractEffect: LowPlant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals~0.45–0.7%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.6–0.85%

Can it cause trouble?

Irritancy
3 strong irritants: Citrus aurantium amara flower oil, Pelargonium graveolens flower oil + 1 more — patch-test recommended
High risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
CocoglyceridesHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skinHigh~2.9–3.6%est.
Hippophae rhamnoides oilA good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.High~0.5–0.75%est.
Citrus aurantium amara flower oilUsed as a fragrance. Can be irritatingHigh~0.3–0.5%est.
Pelargonium graveolens flower oilAn essential oil. Can be irritating. Can become an allergen with oxidationHigh~0.25–0.5%est.
Anthemis nobilis flower oilAn essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skinHigh~0.25–0.4%est.
Tanacetum annuum flower oilAn essential oil that has anti-inflammatory properties but also contains irritating compoundsHigh~0.25–0.45%est.
Candelilla/jojoba/rice bran polyglyceryl-3 estersHelp oil and water mix togetherMedium~1.2–1.4%est.
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~0.75–1.1%est.
Moringa oleifera seed oilA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acidMedium~0.45–0.7%est.
Sodium stearoyl lactylateHelps oil and water mix togetherMedium~0.25–0.45%est.
Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~0.25–0.45%est.
1,2-hexanediolA preservativeMedium~0.15–0.25%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.35%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.5%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.3–5.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Squalane~4.2–5.1%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Cocoglycerides~2.9–3.6%
Irritant · high
Irritation risk
High
Works for
CleansingMoisturizing

Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin

More about Cocoglycerides
Methylheptyl isostearate~2.3–2.8%
Formula
C10-18 triglycerides~1.9–2.3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the skin and attract water to its upper layer. Helps create nice product texture

More about C10-18 triglycerides
Lactobacillus ferment~1.6–1.9%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-oxidationReduces irritation

A fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative

More about Lactobacillus ferment
Lepidium sativum sprout extract~1.4–1.7%
Formula
Candelilla/jojoba/rice bran polyglyceryl-3 esters~1.2–1.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Help oil and water mix together

More about Candelilla/jojoba/rice bran polyglyceryl-3 esters
Glyceryl stearate~1–1.2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Jojoba esters~0.75–1.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Tocopherol~0.6–0.85%
Formula
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-agingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Palmitoyl tripeptide-38~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-38
Argania spinosa sprout cell extract~0.45–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

Plant stem cell extract. Can help attract water to the upper layer of the skin and might be helpful in neutralizing free radicals

More about Argania spinosa sprout cell extract
Leontopodium alpinum meristem cell culture~0.45–0.65%
Formula
Hippophae rhamnoides oil~0.5–0.75%
Key activeIrritant · high
Irritation risk
High
Works for
MoisturizingAnti-oxidation

A good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.

More about Hippophae rhamnoides oil
Moringa oleifera seed oil~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid

More about Moringa oleifera seed oil
Vaccinium vitis-idaea seed oil~0.45–0.65%
Formula
Fructan~0.3–0.6%
Formula
Irritation risk
Low
More about Fructan
Behenyl olivate~0.3–0.55%
Formula
Citrus aurantium amara flower oil~0.3–0.5%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Citrus aurantium amara flower oil
Helichrysum italicum flower oil~0.25–0.45%
Formula
Pelargonium graveolens flower oil~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

An essential oil. Can be irritating. Can become an allergen with oxidation

More about Pelargonium graveolens flower oil
Anthemis nobilis flower oil~0.25–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin

More about Anthemis nobilis flower oil
Tanacetum annuum flower oil~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryMoisturizing

An essential oil that has anti-inflammatory properties but also contains irritating compounds

More about Tanacetum annuum flower oil
Cetearyl alcohol~0.3–0.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Sodium stearoyl lactylate~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl lactylate
Lecithin~0.25–0.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Hydroxypropyl cyclodextrin~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin
Sclerotium gum~0.2–0.4%
Formula
Irritation risk
Low

Used to create gel-like formulas and stabilize emulsions

More about Sclerotium gum
Xanthan gum~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
1,2-hexanediol~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Caprylyl glycol~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Isomalt~0.1–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Isomalt
Sodium phytate~0.1–0.2%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Sodium benzoate~0.1–0.15%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Citric acid~0.05%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ingredient list view

Water, Glycerin, Squalane, Cocoglycerides, Methylheptyl isostearate, C10-18 triglycerides, Lactobacillus ferment, Lepidium sativum sprout extract, Candelilla/jojoba/rice bran polyglyceryl-3 esters, Glyceryl stearate, Jojoba esters, Tocopherol, Palmitoyl tripeptide-38, Argania spinosa sprout cell extract, Leontopodium alpinum meristem cell culture, Hippophae rhamnoides oil, Moringa oleifera seed oil, Vaccinium vitis-idaea seed oil, Fructan, Behenyl olivate, Citrus aurantium amara flower oil, Helichrysum italicum flower oil, Pelargonium graveolens flower oil, Anthemis nobilis flower oil, Tanacetum annuum flower oil, Cetearyl alcohol, Sodium stearoyl lactylate, Lecithin, Hydroxypropyl cyclodextrin, Sclerotium gum, Xanthan gum, 1,2-hexanediol, Caprylyl glycol, Isomalt, Sodium phytate, Sodium benzoate, Citric acid

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Amazon USPrice as of 10/16/2026 00:10 GMT
$100.00
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$124.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NaturopathicaArgan & Peptide Wrinkle Repair CreamYOUR PRODUCTAlpha-HLiquid Gold 24 Hour Moisture Repair CreamMGC DermaBrightening CreamPour Moi SkincareNight Cream
Match—65%59%59%
Price$100.00$51.00−$49.00$26.97−$73.03—
Shared key ingredients—6 of 94 of 93 of 9
Key difference—Lactic AcidCbdPanthenol
Irritancy High Medium Medium Medium
Drying alcohol—— Contains drying alcohol Contains drying alcohol
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Product summary

Judging from the ingredient list, "Naturopathica - Argan & Peptide Wrinkle Repair Cream" works well for improving skin hydration The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (glycerin, isomalt, lactobacillus ferment and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (hippophae rhamnoides oil, jojoba esters, squalane, c10-18 triglycerides and cetearyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We like that this moisturizer contains peptides (palmitoyl tripeptide-38 0.50% - 0.75%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 100.00$ up to 124.00$ in the United States and for 147.50CA$ in Canada.

For a detailed price comparison: click here.

Naturopathica Argan & Peptide Wrinkle Repair Cream
NaturopathicaArgan & Peptide Wrinkle Repair Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.