NassifMD Dermaceuticals Pure Hydration Rejuvenating Night Cream with H2OBioEV

NassifMD Dermaceuticals Pure Hydration Rejuvenating Night Cream with H2OBioEV

Efficacy50/100IrritancyHigh
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Works for

1 of 3 advertised claims delivered

Moisturizing
Panthenol, Dimethicone + 12 more
Strong evidence
What the product description says
“Provides vital hydration to skin at night when it needs it most, helping it look smoother, feel softer, and provide an overall younger looking complexion.”
Source: Skinstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: galactoarabinan, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: bis-diglyceryl polyacyladipate-2, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.25–0.5%
Bis-diglyceryl polyacyladipate-2Key active· Emollient, OcclusiveEffect: HighHelps soften the upper layer of the skin and reduce water loss from its surface~2.5–3%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~6.1–7.4%
GalactoarabinanKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.45–0.65%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2–2.4%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.2–0.35%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.35%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.5–1.8%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.7–2%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1–1.2%
Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~3.2–3.9%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.3%
Aloe barbadensis leaf extractEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.25–0.45%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.4–0.65%
Anti-aging
Tetrahexyldecyl ascorbate
Limited evidence
What the product description says
“Improves the appearance of fine lines and wrinkles, brightens and evens skin tone, and helps soother and calm skin with antioxidants.”
Source: Skinstore

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.

Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.4–0.6%
Evens skin tone
Tetrahexyldecyl ascorbate
Weak evidence
What the product description says
“Improves the appearance of fine lines and wrinkles, brightens and evens skin tone, and helps soother and calm skin with antioxidants.”
Source: Skinstore

Effective ingredients missing or their concentration is too low

Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.4–0.6%

Can it cause trouble?

Irritancy
4 strong irritants: Parfum, Alcohol + 2 more — patch-test recommended
High risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.3%est.
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.2–0.35%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.1–0.2%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.05–0.15%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.1%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~6.1–7.4%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~1.2–1.4%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~0.7–1.05%est.
GalactoarabinanHelps attract water to the upper layer of the skinMedium~0.45–0.65%est.
Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Medium~0.4–0.6%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.2–0.35%est.
Aloe barbadensis leaf extractTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.25–0.45%est.
EthylhexylglycerinA preservativeMedium~0.15–0.3%est.
Potassium sorbateA preservativeMedium~0.15–0.25%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.5–1.8%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~6.1–7.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Propanediol~4–4.9%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Dicaprylyl ether~3.2–3.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether
Bis-diglyceryl polyacyladipate-2~2.5–3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and reduce water loss from its surface

More about Bis-diglyceryl polyacyladipate-2
Glycerin~2–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cetyl alcohol~1.7–2%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Cetearyl alcohol~1.5–1.8%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Cetearyl glucoside~1.2–1.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside
Glyceryl stearate~1–1.2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Sodium acrylates copolymer~0.7–1.05%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Peg-100 stearate~0.65–0.95%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Aphanothece sacrum polysaccharide~0.5–0.75%
Formula
Galactoarabinan~0.45–0.65%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Galactoarabinan
Tetrahexyldecyl ascorbate~0.4–0.6%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin toneAnti-aging

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

More about Tetrahexyldecyl ascorbate
Poria cocos extract~0.35–0.65%
Formula
Lecithin~0.4–0.65%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Polyacrylate-13~0.35–0.6%
Formula
Irritation risk
Low

Used to create a thicker product consistency and stabilize the product formulation

More about Polyacrylate-13
Polyisobutene~0.3–0.55%
Formula
Irritation risk
Low

Used to improve the product consistency

More about Polyisobutene
Polysorbate 20~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Sorbitan isostearate~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Dimethicone~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Tocopheryl acetate~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Allantoin~0.15–0.3%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Parfum~0.15–0.3%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Xanthan gum~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Sodium hyaluronate~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Panthenol~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Sodium phytate~0.2–0.35%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Alcohol~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Maltodextrin~0.2–0.35%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Aloe barbadensis leaf extract~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf extract
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Benzyl alcohol~0.1–0.2%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Potassium sorbate~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Limonene~0.05–0.15%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Linalool~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Ingredient list view

Water, Caprylic/capric triglyceride, Propanediol, Dicaprylyl ether, Bis-diglyceryl polyacyladipate-2, Glycerin, Cetyl alcohol, Cetearyl alcohol, Cetearyl glucoside, Glyceryl stearate, Sodium acrylates copolymer, Peg-100 stearate, Aphanothece sacrum polysaccharide, Galactoarabinan, Tetrahexyldecyl ascorbate, Poria cocos extract, Lecithin, Polyacrylate-13, Polyisobutene, Polysorbate 20, Sorbitan isostearate, Dimethicone, Tocopheryl acetate, Allantoin, Parfum, Xanthan gum, Sodium hyaluronate, Panthenol, Sodium phytate, Alcohol, Maltodextrin, Aloe barbadensis leaf extract, Phenoxyethanol, Ethylhexylglycerin, Benzyl alcohol, Potassium sorbate, Limonene, Linalool

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Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NassifMD DermaceuticalsPure Hydration Rejuvenating Night Cream with H2OBioEVYOUR PRODUCTBotanicsHydration Burst Hydrating Day CreamDerma EHydrating Night Creamendota spaBlue Light Defence Hydro Cream
Match—66%64%64%
Price$75.00$15.99−$59.01$23.60−$51.40$134.85+$59.85
Shared key ingredients—6 of 85 of 86 of 8
Key difference—BetaineRetinyl PalmitateUrea
Irritancy High Medium Medium Medium
Drying alcohol Contains drying alcohol ———
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NassifMD Dermaceuticals Pure Hydration Rejuvenating Night Cream with H2OBioEV
NassifMD DermaceuticalsPure Hydration Rejuvenating Night Cream with H2OBioEV

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