NassifMD Dermaceuticals Pro Peptide Collagen Serum

NassifMD Dermaceuticals Pro Peptide Collagen Serum

Efficacy87/100IrritancyLow

Works for

Moisturizing
N-prolyl palmitoyl tripeptide-56 acetate, Palmitoyl tripeptide-38 + 6 more
Works well
What the product description says
“Improves hydration and strengthen the moisture barrier”
Source: Nassif MD

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": betaine, glycerin.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: n-prolyl palmitoyl tripeptide-56 acetate, palmitoyl tripeptide-38

N-prolyl palmitoyl tripeptide-56 acetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.7–2.5%
Palmitoyl tripeptide-38HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.4–2.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.2–3.2%
Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.95–1.45%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.85–1.25%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.55–1.3%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.5–1.1%
Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~0.4–0.95%
Anti-aging
N-prolyl palmitoyl tripeptide-56 acetate, Palmitoyl tripeptide-38
May help
What the product description says
“Helps minimize the appearance of fine lines & wrinkles, texture and crepiness”
Source: Nassif MD

This product contains n-prolyl palmitoyl tripeptide-56 acetate, palmitoyl tripeptide-38. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

N-prolyl palmitoyl tripeptide-56 acetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.7–2.5%
Palmitoyl tripeptide-38Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.4–2.1%

Can it cause trouble?

Irritancy
6 flagged ingredients
Low risk
We flag 6 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.55–1.3%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.5–1.1%est.
Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~0.4–0.95%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.3%est.
T-butyl alcoholUsed to dissolve other ingredients and to improve smell of products. It could be irritatingMedium~0.05–0.2%est.
EthylhexylglycerinA preservativeMedium~0.05–0.15%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Propanediol~4.7–7%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Glycereth-26~3.4–5.1%
Formula
Irritation risk
Low

Helps create a thicker product consistency

More about Glycereth-26
Peg-6 caprylic/capric glycerides~2.5–3.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps dissolve other ingredients

More about Peg-6 caprylic/capric glycerides
Glycerin~2.2–3.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
N-prolyl palmitoyl tripeptide-56 acetate~1.7–2.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about N-prolyl palmitoyl tripeptide-56 acetate
Palmitoyl tripeptide-38~1.4–2.1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-38
Sodium carboxymethyl beta-glucan~1.6–2.3%
Formula
Irritation risk
Low

Helps thicken the product formulation and create a gel-like texture

More about Sodium carboxymethyl beta-glucan
Sodium acetylated hyaluronate~0.95–1.45%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate
Betaine~0.85–1.25%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Pentylene glycol~0.55–1.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Caprylyl glycol~0.5–1.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Hydroxypropyl cyclodextrin~0.4–0.95%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin
Microcrystalline cellulose~0.4–1%
Formula
Irritation risk
Low
Works for
Exfoliation
More about Microcrystalline cellulose
Cellulose gum~0.2–0.75%
Formula
Irritation risk
Low

Used to create thicker product consistency and stabilize emulsions

More about Cellulose gum
Polyacrylate crosspolymer-6~0.15–0.65%
Formula
Xanthan gum~0.1–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Sodium phytate~0.1–0.35%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Citric acid~0.05–0.3%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
T-butyl alcohol~0.05–0.2%
Irritant · medium
Irritation risk
Medium

Used to dissolve other ingredients and to improve smell of products. It could be irritating

More about T-butyl alcohol
Phenoxyethanol~0.05–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ingredient list view

Water, Propanediol, Glycereth-26, Peg-6 caprylic/capric glycerides, Glycerin, N-prolyl palmitoyl tripeptide-56 acetate, Palmitoyl tripeptide-38, Sodium carboxymethyl beta-glucan, Sodium acetylated hyaluronate, Betaine, Pentylene glycol, Caprylyl glycol, Hydroxypropyl cyclodextrin, Microcrystalline cellulose, Cellulose gum, Polyacrylate crosspolymer-6, Xanthan gum, Sodium phytate, Citric acid, T-butyl alcohol, Phenoxyethanol, Ethylhexylglycerin

Compare prices

Retailers ranked by price — lowest first.

Nassif MD
$60.00
Buy
Amazon USPrice as of 11/13 12:06 GMT
$60.00
Buy
Ulta1 oz
$60.00
Buy

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NassifMD DermaceuticalsPro Peptide Collagen SerumYOUR PRODUCTEveline CosmeticsConcentrated Formula LiftingBeauty PieSuperdrops Flash Face Lift IntenseNiche Beauty labDERMA - PEPTIDES 22% Multi-Peptide Treatment
Match—56%54%45%
Price$60.00—$49.00−$11.00—
Shared key ingredients—4 of 53 of 53 of 5
Key difference—Acetyl Hexapeptide-8Acetyl Hexapeptide-8Acetyl Tetrapeptide-2
Irritancy Low Low Low Medium
Drying alcohol————
View product Shop Shop Shop

More alternatives: Theramid DERMA - PEPTIDES 35%Bielenda Skin Clinic Professional Signaling Peptides

Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 4 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
NassifMD Dermaceuticals Pro Peptide Collagen Serum
NassifMD DermaceuticalsPro Peptide Collagen Serum

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.