Murad Heartleaf Calming Cream

Murad Heartleaf Calming Cream

Efficacy100/100IrritancyLow
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Works for

1 of 1 advertised claim delivered

Moisturizing
Ceramide np, Urea + 11 more
Strong evidence
What the product description says
“instantly calming, comforting cream soothes and softens, helps stabilize sensitive skin, and replenishes with all-day hydration to fortify strength and boost resilience Immediately calms soothes, softens, and refreshes sensitive skin Moisturizes immediately to replenish lost hydration, fortify skin's strength, and boost resilience Reduces signs of skin sensitivity (redness, dryness, itching, stinging, tightening), and skin feels stronger, less reactive, and more comfortable in 1 week Lightweight, silky moisturizer glides delicately over skin, making it ideal for all skin types—including eczema-prone skin”
Source: Murad

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, urea

Vitis vinifera seed oilKey active· EmollientEffect: HighA great emollient that can also have anti-oxidant properties~2.6–3.2%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.45–0.7%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~7.3–8.9%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~1.4–1.7%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.7–5.8%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.45–0.65%
InositolKey active· HumectantEffect: High~0.5–0.75%
Lactobacillus fermentKey active· HumectantEffect: HighA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~0.4–0.65%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.55–0.8%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.7–1.1%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~2.2–2.7%
Lecithin· EmollientEffect: LowUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~1.8–2.2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.55%

Can it cause trouble?

Irritancy
11 flagged ingredients
Low risk
We flag 11 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~7.3–8.9%est.
Glyceryl behenateUsed to create a thicker product consistency and help soften the upper layer of the skinMedium~3.5–4.3%est.
Vitis vinifera seed oilA great emollient that can also have anti-oxidant propertiesMedium~2.6–3.2%est.
TaurineCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectivenessMedium~0.45–0.7%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.3–0.6%est.
EthylhexylglycerinA preservativeMedium~0.25–0.5%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~0.2–0.4%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.35%est.
Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.15–0.3%est.
ChlorphenesinA preservativeMedium~0.15–0.25%est.
Dehydroacetic acidA preservativeMedium~0.1–0.2%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~7.3–8.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glycerin~4.7–5.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Glyceryl behenate~3.5–4.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to create a thicker product consistency and help soften the upper layer of the skin

More about Glyceryl behenate
Vitis vinifera seed oil~2.6–3.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A great emollient that can also have anti-oxidant properties

More about Vitis vinifera seed oil
Behenyl alcohol~2.2–2.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Lecithin~1.8–2.2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Houttuynia cordata extract~1.6–1.9%
Formula
Ceramide np~1.4–1.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Phaeodactylum tricornutum extract~0.8–1.15%
Formula
Urea~0.7–1.1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Yeast amino acids~0.6–0.9%
Formula
Trehalose~0.55–0.8%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Inositol~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Inositol
Taurine~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryAnti-blemishAnti-oxidationEvens skin tone

Could be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness

More about Taurine
Betaine~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Lactobacillus ferment~0.4–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatoryReduces irritation

A fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative

More about Lactobacillus ferment
Helianthus annuus seed oil~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Hydroxyacetophenone~0.3–0.6%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Tocopherol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Ethylhexylglycerin~0.25–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Propanediol~0.25–0.5%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Sodium acrylates copolymer~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Xanthan gum~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Citric acid~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Leuconostoc/radish root ferment filtrate~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate
Chlorphenesin~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Dehydroacetic acid~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Dehydroacetic acid
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ingredient list view

Water, Caprylic/capric triglyceride, Glycerin, Glyceryl behenate, Vitis vinifera seed oil, Behenyl alcohol, Lecithin, Houttuynia cordata extract, Ceramide np, Phaeodactylum tricornutum extract, Urea, Yeast amino acids, Trehalose, Inositol, Taurine, Betaine, Lactobacillus ferment, Helianthus annuus seed oil, Hydroxyacetophenone, Tocopherol, Ethylhexylglycerin, Propanediol, Sodium acrylates copolymer, Xanthan gum, Citric acid, Leuconostoc/radish root ferment filtrate, Chlorphenesin, Dehydroacetic acid, Sodium benzoate

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Amazon USPrice as of 10/23/2026 21:04 GMT
$65.00
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Murad
$65.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MuradHeartleaf Calming CreamYOUR PRODUCTEucerinRoughness Relief CreamPaula's choiceRESIST Barrier Repair Advanced MoisturiserNeogenisisBarrier Renewal Cream
Match—55%53%53%
Price$62.88$11.90−$50.98$46.59−$16.29$197.50+$134.62
Shared key ingredients—5 of 115 of 114 of 11
Key difference—Lactic AcidAdenosinePanthenol
Irritancy Low Low Low Low
Drying alcohol————
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Product summary

Based on the ingredients included, "Murad - Heartleaf Calming Cream" works well for moisturizing the skin. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (urea, betaine, glycerin, inositol and lactobacillus ferment) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide np, vitis vinifera seed oil, caprylic/capric triglyceride, helianthus annuus seed oil and lecithin) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • Another benefit is that this moisturizer contain ceramides (ceramide np 1.40% - 1.70%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Murad" is cruelty free, but its parent company is not.

Price

The product retails for 65.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
    Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
  5. 5
  6. 6

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As an Amazon Associate, WIMJ earns from qualifying purchases.