Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Anti-oxidation
Doesn't work for:
based on ingredients and %- Anti-blemish
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 1
Key actives
Product Summary
"MIGUHARA - Anti Wrinkle Perfect Ampoule Origin" is effective for: Anti-aging and Moisturizing
Ingredient callouts
- Peptides (palmitoyl pentapeptide-4 0.05% - 0.20%, palmitoyl tripeptide-1 0.10% - 0.35%, copper tripeptide-1 0.05% - 0.30%, palmitoyl tetrapeptide-7 0.10% - 0.45% and acetyl hexapeptide-8 0.10% - 0.40%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Adenosine 0.35% - 0.80%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
- Panthenol (pro-vitamin B5) at about 1.50% - 2.20% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.
- Humectants (acetyl hexapeptide-8 0.10% - 0.40%, tremella fuciformis sporocarp extract 0.15% - 0.55%, hydrolyzed collagen 0.35% - 0.85%, carnosine 0.35% - 0.85%, sodium hyaluronate 0.45% - 1.05%, panthenol 1.50% - 2.20% and glycerin 2.50% - 3.80%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 21.70$ in the United States.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
Anti Wrinkle Perfect Ampoule Origin
Source: From product name
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, carnosine, copper tripeptide-1, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
Anti-oxidation
This product contains antioxidants (carnosine) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
Mushroom extract that helps attract water to the upper layer of the skin
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Plant extract that might help neutralize free radicals and support skin barrier function, but research on its effectiveness in skin is lacking
Used to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating
A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating
Moisturizing
What does the product description say?
Bestsellers include the Ultra Whitening Ampoule Origin that brightens skin and blurs blemishes, and the Big 3 Step Whitening Mask Pack that brightens and moisturizes skin while enhancing skin elasticity. All
Source: Yesstyle
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
carnosine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: hydrolyzed collagen.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, panthenol
A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps attract water to the upper layer of the skin and can help improve skin barrier function
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Mushroom extract that helps attract water to the upper layer of the skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps to attract water to the upper layer of the skin. Can add sweet taste to lip products
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Used to add a nice rose smell to the product. Might help attract water to the upper layer of the skin and have some anti-oxidant effect. Can be irritating
Plant extract that might help neutralize free radicals and support skin barrier function, but research on its effectiveness in skin is lacking
A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin
Used as a fragrance. Can be irritating
Anti-blemish
What does the product description say?
Bestsellers include the Ultra Whitening Ampoule Origin that brightens skin and blurs blemishes, and the Big 3 Step Whitening Mask Pack that brightens and moisturizes skin while enhancing skin elasticity. All
Source: Yesstyle
Effective ingredients missing or their concentration is too low.
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Anti-blemish |
Total Promises Fulfilled score: 66/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 MIGUHARA Anti Wrinkle Perfect Ampoule Origin | Current | $21.70 | |
 Matkas Korean Triple Pure Hyaluronic Acid Serum for Face + 2% Niacinamide B3 + Vitamin B5 + 8 Peptides for Deep Firming, Plump Wrinkles, Hydrating Dewy Skin, Anti Aging Acido Hialuronico Facial Serum | 58% | - | |
 Carenology 95 RE:BLUE Deep Concentrate Ampoule | 58% | $65.31 | |
 Hanskin Collagen Peptide Hydra Ampoule | 56% | $28.00 | |
 Orbyt Skin Age Defense Face Serum | 55% | $22.00 | |
Elishacoy Premium Gold Collagen Ampoule | 55% | $15.72 |
Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Unknown, Rosa damascena flower water, Water, Dipropylene glycol, Butylene glycol, Glycerin, Ammonium acryloyldimethyltaurate/vp copolymer, Panthenol, Glycosyl trehalose, Peg-60 hydrogenated castor oil, Hydroxyacetophenone, Hydrogenated starch hydrolysate, Rosa damascena flower oil, Unknown, Sodium hyaluronate, Carrageenan, Dextrin, Ethylhexylglycerin, Carnosine, Adenosine, Sodium polyacrylate, Pvm/ma copolymer, Zingiber officinale extract, Ophiopogon japonicus root extract, Panax ginseng root extract, Citrus grandis extract, Rosa damascena flower extract, Hydrolyzed collagen, Tremella fuciformis sporocarp extract, Acetyl hexapeptide-8, Hexanediol, Palmitoyl tetrapeptide-7, Copper tripeptide-1, Palmitoyl tripeptide-1, Palmitoyl pentapeptide-4
- Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extracts
- Glycerol and the skin: holistic approach to its origin and functions
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Safety assessment of hydrogenated starch hydrolysates
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and l-carnosine in ophthalmic and skin care products
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Effects of steroidal saponins extract from Ophiopogon japonicus root ameliorates doxorubicin-induced chronic heart failure by inhibiting oxidative stress and inflammatory response
- Cosmetic use of an ophiopogon japonicus active principle
- Ginseng in Dermatology: A Review
- Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin
- Carboxymethylation of polysaccharides from Tremella fuciformis for antioxidant and moisture-preserving activities
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
- Topical Peptide Treatments with Effective Anti-Aging Results
- Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds