Manyo https://manyo.us/collections/cream/products/panthetoin-cream

https://manyo.us/collections/cream/products/panthetoin-cream

Efficacy 100/100·Medium irritancy

Efficacy measures how well the formula delivers the claims the brand advertises · 1 of 1 advertised claim delivered

Based on the ingredients included, "Manyo - https: //manyo. Us/collections/cream/products/panthetoin-cream" works well for moisturizing the skin.

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Product summary

Based on the ingredients included, "Manyo - https: //manyo. Us/collections/cream/products/panthetoin-cream" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Acetyl glucosamine, panthenol, glycerin, hydrolyzed hyaluronic acid and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, phytosphingosine, bis-diglyceryl polyacyladipate-2, helianthus annuus seed oil and squalane) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • As a plus, this moisturizer also contains Ceramides (phytosphingosine 0.25% - 0.50% and ceramide np 0.25% - 0.45%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • An effective concentration of Panthenol (pro-vitamin B5) - about 1.30% - 1.60%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, dipotassium glycyrrhizate and allantoin

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 42.00$ in the United States.

For a detailed price comparison: click here.

Product claims breakdown

Moisturizing
14 ingredients contribute at the levels below
Strong evidence

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hydrolyzed hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: bis-diglyceryl polyacyladipate-2, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, ceramide np, panthenol, phytosphingosine

PANTHENOLRole: HeroHelps attract water to the upper layer of the skin and can help improve skin barrier function~1.3–1.6%
PHYTOSPHINGOSINERole: Key activeA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%
CERAMIDE NPRole: Key activeA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%
ACETYL GLUCOSAMINERole: Key activeAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
ECTOINRole: Key activeSoftens the upper layer of the skin and can support skin barrier function~0.3–0.6%
GLYCERINRole: Key activeOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.2–5.1%
HELIANTHUS ANNUUS SEED OILRole: Key activeA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.55%
HYDROLYZED HYALURONIC ACIDRole: Key activeOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.45%
MANGIFERA INDICA SEED BUTTERRole: Key activeHelps to soften the upper layer of the skin and might have some anti-oxidant effect~1.5–1.9%
POLYMETHYLSILSESQUIOXANERole: Key activeA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~0.55–0.85%
SQUALANERole: Key activeAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.3–0.55%
ALLANTOINRole: Under-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.35%
BIS-DIGLYCERYL POLYACYLADIPATE-2Role: Key activeHelps soften the upper layer of the skin and reduce water loss from its surface~0.25–0.5%
DIPOTASSIUM GLYCYRRHIZATERole: Under-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.35%
Anti-aging
ACETYL GLUCOSAMINE at ~0.25–0.45% delivers this without it being on the label
Quiet bonus

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

ACETYL GLUCOSAMINERole: Key activeAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
GlycerinRole: Key activeOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.2–5.1%
Butylene glycol dicaprylate/dicaprateRole: Key activeHelps soften the upper layer of the skin~1.9–2.3%
Mangifera indica seed butterRole: Key activeHelps to soften the upper layer of the skin and might have some anti-oxidant effect~1.5–1.9%
PanthenolRole: Key activeHelps attract water to the upper layer of the skin and can help improve skin barrier function~1.3–1.6%
PolymethylsilsesquioxaneRole: Key activeA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~0.55–0.85%
EctoinRole: Key activeSoftens the upper layer of the skin and can support skin barrier function~0.3–0.6%
Helianthus annuus seed oilRole: Key activeA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.55%
Hydrolyzed hyaluronic acidRole: Key activeOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.45%
SqualaneRole: Key activeAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.3–0.55%
Ceramide npRole: Key activeA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%
PhytosphingosineRole: Key activeA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%
Bis-diglyceryl polyacyladipate-2Role: Key activeHelps soften the upper layer of the skin and reduce water loss from its surface~0.25–0.5%
Cetearyl alcoholRole: Key activeA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.15–0.3%
Evens skin tone
ACETYL GLUCOSAMINE at ~0.25–0.45% delivers this without it being on the label
Quiet bonus

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

ACETYL GLUCOSAMINERole: Key activeAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
DIPOTASSIUM GLYCYRRHIZATERole: Under-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.35%
GlycerinRole: Key activeOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.2–5.1%
Butylene glycol dicaprylate/dicaprateRole: Key activeHelps soften the upper layer of the skin~1.9–2.3%
Mangifera indica seed butterRole: Key activeHelps to soften the upper layer of the skin and might have some anti-oxidant effect~1.5–1.9%
PanthenolRole: Key activeHelps attract water to the upper layer of the skin and can help improve skin barrier function~1.3–1.6%
PolymethylsilsesquioxaneRole: Key activeA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~0.55–0.85%
EctoinRole: Key activeSoftens the upper layer of the skin and can support skin barrier function~0.3–0.6%
Helianthus annuus seed oilRole: Key activeA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.55%
Hydrolyzed hyaluronic acidRole: Key activeOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.45%
SqualaneRole: Key activeAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.3–0.55%
Ceramide npRole: Key activeA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%
PhytosphingosineRole: Key activeA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%
Bis-diglyceryl polyacyladipate-2Role: Key activeHelps soften the upper layer of the skin and reduce water loss from its surface~0.25–0.5%
Cetearyl alcoholRole: Key activeA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.15–0.3%
Irritancy
11 low-risk flags; mostly mild
Some risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureLow~2.3–2.8%est.
Polyglyceryl-3 methylglucose distearateHelps water and oil mix togetherLow~0.9–1.1%est.
MethylpropanediolHelps dissolve other ingredients in a formulationLow~0.55–0.8%est.
1,2-hexanediolA preservativeLow~0.4–0.6%est.
Calcium chlorideHelps create a thicker product consistency. Might be irritatingLow~0.2–0.4%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishLow~0.2–0.4%est.
Caprylyl glycolHelps preserve products and creates a nice product textureLow~0.25–0.45%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureLow~0.2–0.4%est.
EthylhexylglycerinA preservativeLow~0.2–0.4%est.
Trisodium ethylenediamine disuccinateUsed to improve stability of the formulationLow~0.15–0.3%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Low~0.1–0.2%est.
Comedogenic
Cetearyl alcohol ~0.15–0.3% — rinse-off or low %
Low risk
We flag 1 ingredient with a low-to-moderate comedogenic rating — at these concentrations, or in rinse-off use, they're unlikely to clog pores for most skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product textureMed~0.15–0.3%est.
~ marks concentrations estimated from label position and typical use levels

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Glycerin~4.2–5.1%
Key active
Caprylyl methicone~4.1–5%
Formula
Octyldodecanol~3–3.7%
Formula
Pentylene glycol~2.3–2.8%
Low-irritation
Butylene glycol dicaprylate/dicaprate~1.9–2.3%
Key active
Mangifera indica seed butter~1.5–1.9%
Key active
Panthenol~1.3–1.6%
Key active
Pentaerythrityl tetraethylhexanoate~1.2–1.4%
Formula
Polyglyceryl-3 methylglucose distearate~0.9–1.1%
Low-irritation
Behenyl alcohol~0.7–1.05%
Formula
Methylpropanediol~0.55–0.8%
Low-irritation
Polymethylsilsesquioxane~0.55–0.85%
Key active
1,2-hexanediol~0.4–0.6%
Low-irritation
Candida bombicola/glucose/methyl rapeseedate ferment~0.5–0.75%
Formula
Yeast ferment extract~0.35–0.6%
Formula
Ectoin~0.3–0.6%
Key active
Macadamia integrifolia seed oil~0.35–0.6%
Under-dosed
Helianthus annuus seed oil~0.3–0.55%
Key active
Hydrolyzed hyaluronic acid~0.25–0.45%
Key active
Acetyl glucosamine~0.25–0.45%
Key active
Squalane~0.3–0.55%
Key active
Allantoin~0.2–0.35%
Under-dosed
Ceramide np~0.25–0.45%
Key active
Hydroxyphenyl propamidobenzoic acid~0.2–0.4%
Formula
Sodium chloride~0.25–0.45%
Formula
Butylene glycol~0.2–0.4%
Formula
Sodium bicarbonate~0.3–0.55%
Formula
Calcium chloride~0.2–0.4%
Low-irritation
Potassium chloride~0.25–0.45%
Formula
Phytosphingosine~0.25–0.5%
Key active
Cetearyl olivate~0.25–0.45%
Formula
Sorbitan olivate~0.25–0.45%
Formula
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.2–0.4%
Low-irritation
Bis-diglyceryl polyacyladipate-2~0.25–0.5%
Key active
Glyceryl stearate~0.25–0.5%
Formula
Polyglyceryl-3 distearate~0.25–0.45%
Formula
Ammonium acryloyldimethyltaurate/vp copolymer~0.2–0.4%
Formula
Caprylyl glycol~0.25–0.45%
Low-irritation
Cetearyl glucoside~0.2–0.4%
Low-irritation
Ethylhexylglycerin~0.2–0.4%
Low-irritation
Dipotassium glycyrrhizate~0.2–0.35%
Under-dosed
Sorbitan isostearate~0.2–0.35%
Formula
Glyceryl stearate citrate~0.25–0.45%
Formula
Trisodium ethylenediamine disuccinate~0.15–0.3%
Low-irritation
Tocopherol~0.15–0.3%
Formula
Dipropylene glycol~0.1–0.2%
Formula
Propanediol~0.15–0.3%
Formula
Ascorbyl palmitate~0.1–0.2%
Low-irritation
Cetearyl alcohol~0.15–0.3%
Key activeComedo · medium
Stearyl alcohol~0.1–0.2%
Formula
Xanthan gum~0.05–0.1%
Formula

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