Manuka Doctor ApiRefine Targeted Wrinkle Filler

Manuka Doctor ApiRefine Targeted Wrinkle Filler

Efficacy37/100IrritancyMedium

Works for

Moisturizing
Cyclopentasiloxane, Mel + 6 more
Works
What the product description says
“Infused with the signature ingredients of Purified Bee Venom TM and Manuka Honey, it seeks to stimulate natural collagen synthesis, which increases elasticity and moisturization.”
Source: Skinstore

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin, honey.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~7.2–8.7%
MelKey active· Humectant, EmollientEffect: MediumHelps to soften the upper layer of the skin and attract water to it~4.2–5.2%
HoneyKey active· HumectantEffect: MediumHelps attract water to the skin and might have some anti-bacterial properties. Can be an allergen~3.1–3.8%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.5–3%
PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~0.8–1.2%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.55–0.8%
Paraffin· OcclusiveEffect: LowPrevents water loss from the skin surface and thickens the product consistency~0.45–0.65%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.45%
Anti-aging
ACETYL OCTAPEPTIDE-3
Not delivered
What the product description says
“Forget about expensive surgery and fillers; this advanced anti-aging serum works to diminish the look of fine lines in just 30 minutes with a powerful blend of natural ingredients and skincare technology.”
Source: Skinstore

Effective ingredients missing or their concentration is too low.

ACETYL OCTAPEPTIDE-3Key activeEffect: Medium—

Can it cause trouble?

Irritancy
1 strong irritant: Alcohol denat.
Medium risk
We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~1.5–1.8%est.
Acrylates copolymerUsed to stabilize product formulation, help create an even product layer over skin (for example, in sunscreen) and create a thicker product consistencyMedium~1.7–2.1%est.
PolyacrylamideUsed to improve product texture and help oil and water mix togetherMedium~1.1–1.3%est.
Disodium edtaStabilizes the product formulationMedium~0.45–0.65%est.
EthylhexylglycerinA preservativeMedium~0.45–0.65%est.
Laureth-7Helps oil and water mix togetherMedium~0.4–0.6%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.3–0.55%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.45%est.
1,2-hexanediolA preservativeMedium~0.15–0.25%est.
Potassium sorbateA preservativeMedium~0.15–0.25%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Cyclopentasiloxane~7.2–8.7%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Mel~4.2–5.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and attract water to it

More about Mel
Honey~3.1–3.8%
Key active
Irritation risk
Low
Works for
MoisturizingAntibacterial

Helps attract water to the skin and might have some anti-bacterial properties. Can be an allergen

More about Honey
Glycerin~2.5–3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Silica~2.2–2.6%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
Acrylates copolymer~1.7–2.1%
Irritant · medium
Irritation risk
Medium

Used to stabilize product formulation, help create an even product layer over skin (for example, in sunscreen) and create a thicker product consistency

More about Acrylates copolymer
Alcohol denat.~1.5–1.8%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Phenoxyethanol~0.5–1%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Polyacrylamide~1.1–1.3%
Irritant · medium
Irritation risk
Medium

Used to improve product texture and help oil and water mix together

More about Polyacrylamide
Polymethylsilsesquioxane~0.8–1.2%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane
Ammonium acryloyldimethyltaurate/vp copolymer~0.6–0.9%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Butylene glycol~0.55–0.8%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Paraffin~0.45–0.65%
Formula
Irritation risk
Low
Works for
Moisturizing

Prevents water loss from the skin surface and thickens the product consistency

More about Paraffin
Panicum miliaceum seed extract~0.45–0.65%
Formula
Disodium edta~0.45–0.65%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Ethylhexylglycerin~0.45–0.65%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Laureth-7~0.4–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Laureth-7
Citric acid~0.3–0.55%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Vp/polycarbamyl polyglycol ester~0.25–0.5%
Formula
Hydrolyzed sesame protein pg-propyl methylsilanediol~0.25–0.45%
Formula
Opuntia ficus-indica stem extract~0.25–0.45%
Formula
Caprylyl glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Tannic acid~0.2–0.35%
Formula
Irritation risk
Low
More about Tannic acid
1,2-hexanediol~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Bee venom~0.15–0.3%
Formula
Irritation risk
Low
More about Bee venom
Potassium sorbate~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Acetyl
Not recognized
Octapeptide-3~0.1–0.15%
Formula
Irritation risk
Low
More about Octapeptide-3
Ingredient list view

Water, Cyclopentasiloxane, Mel, Honey, Glycerin, Silica, Acrylates copolymer, Alcohol denat., Phenoxyethanol, Polyacrylamide, Polymethylsilsesquioxane, Ammonium acryloyldimethyltaurate/vp copolymer, Butylene glycol, Paraffin, Panicum miliaceum seed extract, Disodium edta, Ethylhexylglycerin, Laureth-7, Citric acid, Vp/polycarbamyl polyglycol ester, Hydrolyzed sesame protein pg-propyl methylsilanediol, Opuntia ficus-indica stem extract, Caprylyl glycol, Tannic acid, 1,2-hexanediol, Bee venom, Potassium sorbate, Unknown, Octapeptide-3

Compare prices

Retailers ranked by price — lowest first.

🇦🇺 Amazon Australia (AU)
Price unavailable Out of stock
Check

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Manuka DoctorApiRefine Targeted Wrinkle FillerYOUR PRODUCTLANEIGEFresh Calming Mousse MoisturizerMary&MayShea Butter & Rice Bran Body Cream 250mle.l.f. CosmeticsHappy Hydration Face Cream
Match—29%27%27%
Price——$22.82$30.65
Shared key ingredients—3 of 32 of 32 of 3
Key difference—PanthenolCeramide NpNiacinamide
Irritancy Medium Low Low Low
Drying alcohol Contains drying alcohol ———
View product Shop Shop Shop

More alternatives: Olay Collagen Peptide Day CreamLa Roche-Posay Redermic C Eyes Anti-Wrinkle Firming Moisturizing Filler

Cheaper alternatives? Browse formulas in the same category.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder
Manuka Doctor ApiRefine Targeted Wrinkle Filler
Manuka DoctorApiRefine Targeted Wrinkle Filler

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.