Make P:rem

Make P:rem Safe Me. Relief Intensive CP Cream

Name: Make P:rem - Safe Me. Relief Intensive CP Cream
Brand: Make P:rem

Efficacy100/100IrritancyMedium

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Works for

1 of 1 advertised claim delivered

Moisturizing

Phytosphingosine, Panthenol + 21 more

Strong evidence

What the product description says

“Safe Me. Relief Intensive CP Cream Relief Intensive CP Cream”

From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: cholesterol, cetearyl alcohol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, panthenol, phytosphingosine

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.4–0.6%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.95–1.15%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.8–5.8%

PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.15–0.25%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~3.9–4.8%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.5–0.7%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.6%

CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.25–0.45%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.35–0.6%

Vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~0.75–1.1%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2.5–3%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.15–0.3%

Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~0.55–0.8%

Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.3–0.55%

Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~2.3–2.8%

Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~1.5–1.8%

Neopentyl glycol diheptanoate· EmollientEffect: LowHelps soften the upper layer of the skin and create a nice product consistency~1.9–2.3%

Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.3–0.55%

Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~1.6–2%

C12-16 alcohols· EmollientEffect: LowHelps soften the upper layer of the skin and improve the product's texture~0.25–0.5%

Avena sativa kernel oilUnder-dosedEffect: HighAn effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties~0.45–0.7%

Caprylic/capric triglycerideUnder-dosedEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.65–0.95%

Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.35–0.6%

Can it cause trouble?

Irritancy

1 strong irritant: Peucedanum graveolens extract

Medium risk

We flagged 9 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Peucedanum graveolens extractA plant extract. Might have an antioxidant effect. Can be used as a fragranceHigh~0.45–0.65%est.

1,2-hexanediolA preservativeMedium~0.75–1.1%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.65–0.95%est.

Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.25–0.45%est.

Sodium polyacryloyldimethyl taurateHelps oil and water mix togetherMedium~0.25–0.45%est.

C12-16 alcoholsHelps soften the upper layer of the skin and improve the product's textureMedium~0.25–0.5%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.3%est.

Myristic acidHelps oil and water mix together. Could be comedogenicMedium~0.15–0.3%est.

EthylhexylglycerinA preservativeMedium~0.05–0.1%est.

Comedogenic

3 ingredients rated 2 or more on the 0–5 pore-clogging scale

3 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Myristic acidHelps oil and water mix together. Could be comedogenic3/5~0.15–0.3%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2.5–3%est.

Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~0.55–0.8%est.

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Alternatives

Cheaper, or higher on efficacy

celimax Dual Barrier Skin Wearable Cream 50ml

Cheaper64% match

$14.73

VT Cosmetics VT PDRN Cream 100

Cheaper63% match

$17.98

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~4.8–5.8%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Panthenol~3.9–4.8%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Cetearyl alcohol~2.5–3%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Hydrogenated polydecene~2.3–2.8%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene

Neopentyl glycol diheptanoate~1.9–2.3%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and create a nice product consistency

More about Neopentyl glycol diheptanoate

Dicaprylyl ether~1.6–2%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether

Cyclohexasiloxane~1.5–1.8%

Formula

Irritation risk: Low

Works for

Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane

1,2-hexanediol~0.75–1.1%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Betaine~0.95–1.15%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Vegetable oil~0.75–1.1%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Vegetable oil

Caprylic/capric triglyceride~0.65–0.95%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Glyceryl stearate se~0.55–0.8%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se

Avena sativa kernel oil~0.45–0.7%

Under-dosed

Irritation risk: Low

Works for

Moisturizing

An effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties

More about Avena sativa kernel oil

Peucedanum graveolens extract~0.45–0.65%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract. Might have an antioxidant effect. Can be used as a fragrance

More about Peucedanum graveolens extract

Ceramide np~0.5–0.7%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Hydrolyzed hyaluronic acid~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Hydrolyzed sodium hyaluronate~0.35–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Sodium hyaluronate~0.3–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Hydrogenated lecithin~0.3–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Cetearyl olivate~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Cetearyl olivate

Sorbitan olivate~0.3–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan olivate

Behenyl alcohol~0.3–0.55%

Formula

Irritation risk: Low

Works for

Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol

Pentaerythrityl distearate~0.3–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

More about Pentaerythrityl distearate

Cetearyl glucoside~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside

Palmitic acid~0.3–0.55%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid

Sodium polyacryloyldimethyl taurate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Helps oil and water mix together

More about Sodium polyacryloyldimethyl taurate

C12-16 alcohols~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps soften the upper layer of the skin and improve the product's texture

More about C12-16 alcohols

Stearic acid~0.35–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid

Xanthan gum~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Cholesterol~0.25–0.45%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol

Citric acid~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Glucose~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Fructan~0.15–0.25%

Formula

Irritation risk: Low

More about Fructan

Myristic acid~0.15–0.3%

Comedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

Cleansing

Helps oil and water mix together. Could be comedogenic

More about Myristic acid

Phytosphingosine~0.15–0.25%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-blemishAnti-inflammatory

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine

Ethylhexylglycerin~0.05–0.1%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Ingredient list view

Water, Glycerin, Panthenol, Cetearyl alcohol, Hydrogenated polydecene, Neopentyl glycol diheptanoate, Dicaprylyl ether, Cyclohexasiloxane, 1,2-hexanediol, Betaine, Vegetable oil, Caprylic/capric triglyceride, Glyceryl stearate se, Avena sativa kernel oil, Peucedanum graveolens extract, Ceramide np, Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate, Sodium hyaluronate, Hydrogenated lecithin, Cetearyl olivate, Sorbitan olivate, Behenyl alcohol, Pentaerythrityl distearate, Cetearyl glucoside, Palmitic acid, Sodium polyacryloyldimethyl taurate, C12-16 alcohols, Stearic acid, Xanthan gum, Cholesterol, Citric acid, Glucose, Fructan, Myristic acid, Phytosphingosine, Ethylhexylglycerin

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Make P:remSafe Me. Relief Intensive CP CreamYOUR PRODUCT	celimaxDual Barrier Skin Wearable Cream 50ml	VT CosmeticsVT PDRN Cream 100	COSRXSkin Barrier Moisturizing Cream
Match	—	64%	63%	63%
Price	$34.00	$14.73−$19.27	$17.98−$16.02	$16.86−$17.14
Shared key ingredients	—	7 of 11	10 of 11	9 of 11
Key difference	—	Ceramide Ap	Niacinamide	Ceramide Ap
Irritancy	Medium	Low	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

Based on the ingredient list, "Make P: rem - Safe Me. Relief Intensive CP Cream" can work well for skin moisturization. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (panthenol, betaine, glycerin, hydrolyzed hyaluronic acid and sodium hyaluronate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide np, phytosphingosine, cholesterol, cetearyl alcohol and vegetable oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

Another benefit is that this moisturizer contain ceramides (phytosphingosine 0.15% - 0.25% and ceramide np 0.50% - 0.70%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
An effective concentration of Panthenol (pro-vitamin B5) - about 3.90% - 4.80%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: caprylic/capric triglyceride, avena sativa kernel oil and stearic acid

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.