Leaders Wrinkle Tox Skin Clinic Mask

Leaders Wrinkle Tox Skin Clinic Mask

Efficacy100/100IrritancyHigh

Works for

Anti-aging
Adenosine, Acetyl hexapeptide-8 + 3 more
Works well
What the product description says
“The formula helps turn back the hands of time by improving elasticity and the appearance of wrinkles thanks to ingredients like collagen-boosting adenosine.”
Source: Soko Glam

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, palmitoyl tripeptide-5, tripeptide-1, tripeptide-10 citrulline.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.7%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%
Tripeptide-10 citrullineKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%
Moisturizing
Side benefit · Acetyl hexapeptide-8, Palmitoyl tripeptide-5 + 12 more
Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: tripeptide-1, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, palmitoyl tripeptide-5, tripeptide-1, tripeptide-10 citrulline

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%
Tripeptide-10 citrullineHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~5.1–6.2%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~1.4–1.7%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.7%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.4–0.65%
Hydrolyzed soy proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.15–0.25%
Hydrolyzed wheat proteinKey active· HumectantEffect: MediumCan help attract water to the upper layer of the skin. Avoid if sensitive to gluten~0.15–0.3%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3–3.7%
Portulaca oleracea extract· HumectantEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~1.2–1.4%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.6–0.9%
Gentiana lutea root extractEffect: Low, below effective doseA plant extract that can help strengthen the skin barrier function and improve skin moisture levels~0.25–0.4%

Can it cause trouble?

Irritancy
3 strong irritants: Parfum, Arnica montana flower extract + 1 more — patch-test recommended
High risk
We flagged 15 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~1.9–2.3%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.3–0.6%est.
Arnica montana flower extractA plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skinHigh~0.2–0.35%est.
Achillea millefolium extractPlant extract that can help neutralize free radicals in skin. Can be used as a fragrance. Can be irritatingHigh~0.25–0.5%est.
MethylpropanediolHelps dissolve other ingredients in a formulationMedium~4.2–5.1%est.
Acer saccharum extractA plant extract that contains small percentage of AHAs. Is unlikely to have any skin benefit due the small concentration of the active compoundsMedium~1.6–2%est.
Portulaca oleracea extractA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skinMedium~1.2–1.4%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.95–1.2%est.
EthylhexylglycerinA preservativeMedium~0.7–1.05%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.6–0.9%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.45–0.7%est.
Saururus chinensis extractPlant extract that might have some anti-inflammatory propertiesMedium~0.3–0.55%est.
Gentiana lutea root extractA plant extract that can help strengthen the skin barrier function and improve skin moisture levelsMedium~0.25–0.4%est.
Hydrolyzed wheat proteinCan help attract water to the upper layer of the skin. Avoid if sensitive to glutenMedium~0.15–0.3%est.
1,2-hexanediolA preservativeMedium~0.1–0.2%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ecklonia cava extract—3/5~0.25–0.5%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~5.1–6.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Methylpropanediol~4.2–5.1%
Irritant · medium
Irritation risk
Medium

Helps dissolve other ingredients in a formulation

More about Methylpropanediol
Butylene glycol~3–3.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Dipropylene glycol~2.2–2.7%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Chamomilla recutita flower extract~1.9–2.3%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract
Acer saccharum extract~1.6–2%
Irritant · medium
Irritation risk
Medium

A plant extract that contains small percentage of AHAs. Is unlikely to have any skin benefit due the small concentration of the active compounds

More about Acer saccharum extract
Betaine~1.4–1.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Portulaca oleracea extract~1.2–1.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizing

A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin

More about Portulaca oleracea extract
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.95–1.2%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Ethylhexylglycerin~0.7–1.05%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Caprylyl glycol~0.6–0.9%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Xanthan gum~0.5–0.8%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Adenosine~0.45–0.7%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Sorbitan isostearate~0.45–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Polysorbate 60~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Sodium hyaluronate~0.4–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Parfum~0.3–0.6%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Saururus chinensis extract~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatory

Plant extract that might have some anti-inflammatory properties

More about Saururus chinensis extract
Ledum palustre extract~0.3–0.55%
Formula
Houttuynia cordata extract~0.25–0.5%
Formula
Ecklonia cava extract~0.25–0.5%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
More about Ecklonia cava extract
Artemisia capillaris flower extract~0.25–0.45%
Formula
Acetyl hexapeptide-8~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Gentiana lutea root extract~0.25–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant extract that can help strengthen the skin barrier function and improve skin moisture levels

More about Gentiana lutea root extract
Artemisia absinthium extract~0.2–0.4%
Formula
Arnica montana flower extract~0.2–0.35%
Irritant · high
Irritation risk
High

A plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skin

More about Arnica montana flower extract
Achillea millefolium extract~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Plant extract that can help neutralize free radicals in skin. Can be used as a fragrance. Can be irritating

More about Achillea millefolium extract
Pseudoalteromonas ferment extract~0.2–0.35%
Formula
Palmitoyl tripeptide-5~0.15–0.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Hydrolyzed wheat protein~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Can help attract water to the upper layer of the skin. Avoid if sensitive to gluten

More about Hydrolyzed wheat protein
Hydrolyzed soy protein~0.15–0.25%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatoryEvens skin tone

Helps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing

More about Hydrolyzed soy protein
1,2-hexanediol~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Tripeptide-10 citrulline~0.1–0.15%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-10 citrulline
Tripeptide-1~0.1–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1
Ingredient list view

Water, Glycerin, Methylpropanediol, Butylene glycol, Dipropylene glycol, Chamomilla recutita flower extract, Acer saccharum extract, Betaine, Portulaca oleracea extract, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Ethylhexylglycerin, Caprylyl glycol, Xanthan gum, Adenosine, Sorbitan isostearate, Polysorbate 60, Sodium hyaluronate, Parfum, Saururus chinensis extract, Ledum palustre extract, Houttuynia cordata extract, Ecklonia cava extract, Artemisia capillaris flower extract, Acetyl hexapeptide-8, Gentiana lutea root extract, Artemisia absinthium extract, Arnica montana flower extract, Achillea millefolium extract, Pseudoalteromonas ferment extract, Palmitoyl tripeptide-5, Hydrolyzed wheat protein, Hydrolyzed soy protein, 1,2-hexanediol, Tripeptide-10 citrulline, Tripeptide-1

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
LeadersWrinkle Tox Skin Clinic MaskYOUR PRODUCTnumbuzinNo.9 NAD Bio Lifting-sil Full Face Mask bottom sheetVARUZAReal Natural Sheet Mask with Blue AmpouleSoon SkincareModu Regenerating Face Mask
Match—61%60%60%
Price$5.00—$9.99+$4.99$47.00+$42.00
Shared key ingredients—6 of 85 of 85 of 8
Key difference—Myristoyl Pentapeptide-17Copper Tripeptide-1—
Irritancy High Medium Medium High
Drying alcohol————
View product Shop Shop Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

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Leaders Wrinkle Tox Skin Clinic Mask
LeadersWrinkle Tox Skin Clinic Mask

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.