ISNTREE CICA Relief Cream

ISNTREE CICA Relief Cream

Efficacy66/100IrritancyMedium

Works for

Moisturizing
Palmitoyl tripeptide-1, Sh-oligopeptide-1 + 22 more
Works well
What the product description says
“CICA Relief Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, leontopodium alpinum callus culture extract.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: beeswax, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, palmitoyl tripeptide-1, sh-oligopeptide-1

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Sh-oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.25–0.45%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~7.1–8.7%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~3.3–4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.4–3%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.7–2.1%
BeeswaxKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~1.6–1.9%
Coco-caprylate/caprateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin without creating a greasy texture~1.2–1.5%
Leontopodium alpinum callus culture extractKey active· HumectantEffect: MediumA plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin~0.55–0.8%
Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.3–0.5%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.25–0.4%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.4%
Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~1.9–2.4%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.65–0.95%
Glyceryl caprylate· EmollientEffect: LowAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.3–0.6%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.3–0.55%
Moringa oleifera seed oil· EmollientEffect: LowA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid~0.3–0.55%
C12-16 alcohols· EmollientEffect: LowHelps soften the upper layer of the skin and improve the product's texture~0.25–0.45%
Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.2–0.35%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.1–0.2%
PanthenolUnder-dosedHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.25–0.5%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.4%
Anti-aging
Centella asiatica extract, Palmitoyl tripeptide-1 + 5 more
Works well
What the product description says
“Formulated with 100,000ppm Centella Asiatica Extract and Asiaticoside to protect and hydrate skin Improves skin elasticity and strengthens skin barrier Adenosine reduces appearances of fine lines and wrinkles”
Source: Lila Beauty

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, asiaticoside, centella asiatica extract, copper tripeptide-1, palmitoyl tripeptide-1, sh-oligopeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~7.1–8.7%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.4%
Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.25–0.45%
Sh-oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.25–0.4%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Evens skin tone
No ingredient credited for this claim
Not delivered
What the product description says
“EGF and Peptide also make it a wonderful anti-aging moisturiser, helping to firm skin and evening out skin tone. 50 ml / 1.76 fl oz”
Source: beauty and Seoul

Effective ingredients missing or their concentration is too low

Anti-oxidation
Side benefit · Centella asiatica extract, Asiaticoside + 7 more
Works well

This product contains antioxidants (asiaticoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - centella asiatica extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~7.1–8.7%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.25–0.4%
Leontopodium alpinum callus culture extractEffect: LowA plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin~0.55–0.8%
Coccinia indica fruit extractEffect: LowA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin~0.45–0.65%
Melia azadirachta flower extractEffect: LowA plant extract that might be helpful to neutralize free radicals in skin~0.45–0.65%
Solanum melongena fruit extractEffect: LowEggplant fruit extract. Might have some anti-oxidant effect~0.35–0.65%
Corallina officinalis extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.3–0.5%
Ocimum sanctum leaf extractEffect: LowA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals~0.3–0.55%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.4%

Can it cause trouble?

Irritancy
1 strong irritant: Ocimum sanctum leaf extract
Medium risk
We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.5–0.7%est.
Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.3–0.55%est.
Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.3–0.55%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~7.1–8.7%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.3–4%est.
1,2-hexanediolA preservativeMedium~0.75–1.1%est.
Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.45–0.65%est.
Coccinia indica fruit extractA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skinMedium~0.45–0.65%est.
Solanum melongena fruit extractEggplant fruit extract. Might have some anti-oxidant effectMedium~0.35–0.65%est.
Moringa oleifera seed oilA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acidMedium~0.3–0.55%est.
AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.25–0.4%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.25–0.5%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.25–0.45%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.25–0.45%est.
C12-16 alcoholsHelps soften the upper layer of the skin and improve the product's textureMedium~0.25–0.45%est.
EthylhexylglycerinA preservativeMedium~0.1–0.2%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.3–0.5%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.7–2.1%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Centella asiatica extract~7.1–8.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Reduces rednessReduces irritationMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Dipropylene glycol~4.3–5.3%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Caprylic/capric triglyceride~3.3–4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glycerin~2.4–3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydrogenated polydecene~1.9–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene
Cetearyl alcohol~1.7–2.1%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Beeswax~1.6–1.9%
Key active
Irritation risk
Low
Works for
Moisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Beeswax
Coco-caprylate/caprate~1.2–1.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin without creating a greasy texture

More about Coco-caprylate/caprate
1,2-hexanediol~0.75–1.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Cetearyl olivate~0.7–1.05%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Glyceryl stearate~0.65–0.95%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Leontopodium alpinum callus culture extract~0.55–0.8%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatory

A plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin

More about Leontopodium alpinum callus culture extract
Melia azadirachta leaf extract~0.5–0.7%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract
Melia azadirachta flower extract~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract
Coccinia indica fruit extract~0.45–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin

More about Coccinia indica fruit extract
Amber powder~0.45–0.65%
Formula
Irritation risk
Low

Does not have proven skin benefits

More about Amber powder
Solanum melongena fruit extract~0.35–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

Eggplant fruit extract. Might have some anti-oxidant effect

More about Solanum melongena fruit extract
Curcuma longa root extract~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract
Ocimum sanctum leaf extract~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract
Corallina officinalis extract~0.3–0.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract
Hydrogenated lecithin~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Glyceryl caprylate~0.3–0.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate
Moringa oleifera seed oil~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid

More about Moringa oleifera seed oil
Asiaticoside~0.25–0.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizingAnti-agingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside
Sh-oligopeptide-1~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-1
Acetyl hexapeptide-8~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Palmitoyl tripeptide-1~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Copper tripeptide-1~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1
Phosphatidylcholine~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
Panthenol~0.25–0.5%
Under-dosed
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Allantoin~0.2–0.4%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Palmitic acid~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Cetearyl glucoside~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Adenosine~0.25–0.4%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
C12-16 alcohols~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin and improve the product's texture

More about C12-16 alcohols
Microcrystalline cellulose~0.2–0.4%
Formula
Irritation risk
Low
Works for
Exfoliation
More about Microcrystalline cellulose
Cellulose gum~0.15–0.3%
Formula
Irritation risk
Low

Used to create thicker product consistency and stabilize emulsions

More about Cellulose gum
Dextrin~0.2–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin
Sorbitan olivate~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Butylene glycol~0.1–0.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Ethylhexylglycerin~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ingredient list view

Water, Centella asiatica extract, Dipropylene glycol, Caprylic/capric triglyceride, Glycerin, Hydrogenated polydecene, Cetearyl alcohol, Beeswax, Coco-caprylate/caprate, 1,2-hexanediol, Cetearyl olivate, Glyceryl stearate, Leontopodium alpinum callus culture extract, Melia azadirachta leaf extract, Melia azadirachta flower extract, Coccinia indica fruit extract, Amber powder, Solanum melongena fruit extract, Curcuma longa root extract, Ocimum sanctum leaf extract, Corallina officinalis extract, Hydrogenated lecithin, Glyceryl caprylate, Moringa oleifera seed oil, Asiaticoside, Sh-oligopeptide-1, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Copper tripeptide-1, Phosphatidylcholine, Panthenol, Allantoin, Palmitic acid, Cetearyl glucoside, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Adenosine, Xanthan gum, C12-16 alcohols, Microcrystalline cellulose, Cellulose gum, Dextrin, Sorbitan olivate, Butylene glycol, Ethylhexylglycerin

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

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ISNTREECICA Relief CreamYOUR PRODUCTSaturday SkinMulti Peptide Repair Treatment CreamTOSOWOONGCica Snail CreamNEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream
Match—59%59%57%
Price$26.48$29.90+$3.42$16.40−$10.08$60.00+$33.52
Shared key ingredients—8 of 1411 of 149 of 14
Key difference—Sh-Polypeptide-45MadecassosideHexapeptide-11
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Product summary

"ISNTREE - CICA Relief Cream" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. ISNTREE - CICA Relief Cream ticks this box. Acetyl hexapeptide-8, glycerin, leontopodium alpinum callus culture extract, butylene glycol and dextrin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (palmitoyl tripeptide-1, beeswax, caprylic/capric triglyceride, cetearyl alcohol and coco-caprylate/caprate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This moisturizer also contains Peptides (acetyl hexapeptide-8 0.25% - 0.45%, sh-oligopeptide-1 0.25% - 0.45%, palmitoyl tripeptide-1 0.30% - 0.55% and copper tripeptide-1 0.25% - 0.45%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
  • Adenosine 0.25% - 0.40%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
  • Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiaticoside 0.25% - 0.40% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: allantoin

Irritation risk

There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "ISNTREE" is cruelty free and so is its parent company.

Price

The product retails for 26.50A$ in Australia and for 26.48$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 28 studies and safety reviews.

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ISNTREE CICA Relief Cream
ISNTREECICA Relief Cream

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