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Product summary

Based on the ingredients included, "ISNTREE - CICA Relief Cream" works well for moisturizing the skin. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. ISNTREE - CICA Relief Cream ticks this box. Acetyl hexapeptide-8, glycerin, leontopodium alpinum callus culture extract, butylene glycol and dextrin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (palmitoyl tripeptide-1, beeswax, caprylic/capric triglyceride, cetearyl alcohol and coco-caprylate/caprate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We like that this moisturizer contains peptides (acetyl hexapeptide-8 0.25% - 0.45%, sh-oligopeptide-1 0.25% - 0.45%, palmitoyl tripeptide-1 0.30% - 0.55% and copper tripeptide-1 0.25% - 0.45%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Adenosine 0.25% - 0.40%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
  • Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiaticoside 0.25% - 0.40% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: allantoin

Irritation risk

This moisturizer contains actives that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "ISNTREE" is cruelty free and so is its parent company.

Price

The product retails from 16.67£ up to 22.99£ in the United Kingdom, for 26.50A$ in Australia and for 33.10$ in the United States.

For a detailed price comparison: click here.