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ISDIN Ureadin Manos Plus Handcreme Repair
ISDIN

ISDIN Ureadin Manos Plus Handcreme Repair

Efficacy87/100IrritancyHigh
See all ingredients

Works for

Moisturizing
Panthenol, Urea + 9 more
Works well
What the product description says
“Spendet tiefenwirksam Feuchtigkeit, macht die Hände weich und repariert sehr trockene und empfindliche Haut.”
Source: ISDIN

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: paraffinum liquidum, cetearyl alcohol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol, paraffinum liquidum, urea

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~1–1.5%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.85–1.3%
Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~0.55–1.25%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.7%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~1.4–2.1%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.1–1.7%
Dimethicone crosspolymerKey activeEffect: MediumUsed to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface~0.2–0.7%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.05–0.3%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~0.15–0.65%
PetrolatumUnder-dosedOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~0.45–1.1%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.35–0.8%
Anti-aging
Ubiquinone, Lactic acid
May help
What the product description says
“Coenzym Q10 Antioxidativer Inhaltsstoff mit regenerierender und Anti-Aging-Wirkung.”
Source: ISDIN

This product contains ubiquinone. This ingredient help neutralize free radicals in skin. By doing so, they might be able to prevent early signs of aging (like fine lines and wrinkles), at least to some extent. These ingredients will not be able to "reverse" signs of aging.

UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.05–0.3%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.35–0.8%
Anti-oxidation
Side benefit · Ubiquinone
Works well

This product contains antioxidants (ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.05–0.3%

Can it cause trouble?

Irritancy
8 strong irritants: Parfum, Limonene + 6 more — patch-test recommended
High risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.3%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.05–0.3%est.
Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.05–0.25%est.
CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.01–0.05%est.
CitralA fragrance with a lemon scent. A likely irritantHigh~0.01–0.05%est.
LinaloolA fragrance. Can be irritatingHigh~0.01–0.05%est.
Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.01–0.05%est.
Isoeugenol—High~0.01–0.05%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.35–0.8%est.
Sodium cetearyl sulfateHelps water and oil mix together and works as a cleansing agentMedium~0.35–0.85%est.
EthylhexylglycerinA preservativeMedium~0.1–0.4%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.1–1.7%est.
Alternatives
Cheaper, or higher on efficacy
KINUHADAKOMACHI Hand & Heel Cream Jar Type
STH KINUHADAKOMACHI Hand & Heel Cream Jar Type
Higher efficacy · 100/10054% match
$39.27
Mamolly Hand Cream Moist
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Ingredients

Filter by role to see what each ingredient is doing.

Urea~27–41%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Ubiquinone~7.8–11.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone
Panthenol~3.1–4.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Water~2.3–3.4%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~1.8–2.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cyclopentasiloxane~1.4–2.1%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Cetearyl alcohol~1.1–1.7%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Panthenol~1–1.5%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Urea~0.85–1.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Paraffinum liquidum~0.55–1.25%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Petrolatum~0.45–1.1%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Lactic acid~0.35–0.8%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneExfoliationMoisturizingAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Ammonium acryloyldimethyltaurate/vp copolymer~0.35–0.75%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Phenoxyethanol~0.3–0.7%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Dimethicone crosspolymer~0.2–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface

More about Dimethicone crosspolymer
Octyldodecanol~0.15–0.65%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Sodium cetearyl sulfate~0.35–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together and works as a cleansing agent

More about Sodium cetearyl sulfate
Sodium hydroxide~0.15–0.6%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Ethylhexylglycerin~0.1–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Parfum~0.05–0.3%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Limonene~0.05–0.3%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Hexyl cinnamal~0.05–0.25%
Irritant · high
Irritation risk
High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal
Ubiquinone~0.05–0.3%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone
Coumarin~0.01–0.05%
Irritant · high
Irritation risk
High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin
Citral~0.01–0.05%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
Linalool~0.01–0.05%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Alpha-isomethyl ionone~0.01–0.05%
Irritant · high
Irritation risk
High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone
Isoeugenol~0.01–0.05%
Irritant · high
Irritation risk
High
More about Isoeugenol
Ingredient list view

Urea, Ubiquinone, Panthenol, Water, Glycerin, Cyclopentasiloxane, Cetearyl alcohol, Panthenol, Urea, Paraffinum liquidum, Petrolatum, Lactic acid, Ammonium acryloyldimethyltaurate/vp copolymer, Phenoxyethanol, Dimethicone crosspolymer, Octyldodecanol, Sodium cetearyl sulfate, Sodium hydroxide, Ethylhexylglycerin, Parfum, Limonene, Hexyl cinnamal, Ubiquinone, Coumarin, Citral, Linalool, Alpha-isomethyl ionone, Isoeugenol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ISDINUreadin Manos Plus Handcreme RepairYOUR PRODUCTSTHKINUHADAKOMACHI Hand & Heel Cream Jar TypeNeutrogenaExpress Absorption Hand CreamCosme StationMamolly Hand Cream Moist
Match—54%54%52%
Price—$39.27$15.22$7.42
Shared key ingredients—5 of 81 of 84 of 8
Key difference—TriethylhexanoinIsopropyl MyristateCeramide Np
Irritancy High Medium Medium Medium
Drying alcohol——— Contains drying alcohol
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 8 studies and safety reviews.

  1. 1
    Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
  2. 2
    Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
  3. 3
    Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
  4. 4
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  5. 5
    A review on the extensive skin benefits of mineral oilncbi.nlm.nih.gov
  6. 6
    Epidermal and dermal effects of topical lactic acidncbi.nlm.nih.gov
ISDIN Ureadin Manos Plus Handcreme Repair
ISDINUreadin Manos Plus Handcreme Repair
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