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ISANA Handcreme Night & Beauty
ISANA

ISANA Handcreme Night & Beauty

Efficacy100/100IrritancyMedium
See all ingredients

Works for

Moisturizing
Panthenol, Glycerin + 9 more
Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, propylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, isopropyl myristate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.95–1.4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.7–5.5%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~3.1–4.7%
Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~1.6–2.5%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.4–2.1%
Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~0.4–0.9%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.4–3.6%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~2–2.9%
Ethylhexyl stearate· EmollientEffect: LowHelps soften the upper layer of the skin~1.2–1.7%
Argania spinosa kernel oilUnder-dosedAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.35–0.8%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.35–0.85%

Can it cause trouble?

Irritancy
2 strong irritants: Lavandula angustifolia flower extract, Parfum
Medium risk
We flagged 8 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~2–2.9%est.
Lavandula angustifolia flower extractEssential oil that can be irritatingHigh~0.45–1%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.55%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.05–0.2%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.8–1.2%est.
Argania spinosa kernel oilAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant propertiesMedium~0.35–0.8%est.
Sodium cetearyl sulfateHelps water and oil mix together and works as a cleansing agentMedium~0.2–0.75%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.01–0.1%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~1.6–2.5%est.
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.4–2.1%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~3.1–4.7%est.
Alternatives
The closest match we found
Dermatologic Enydrial Hand Cream
RoC Skincare Dermatologic Enydrial Hand Cream
Closest match66% match
$6.41
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.7–5.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cetearyl alcohol~3.1–4.7%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Glyceryl stearate~2.4–3.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Propylene glycol~2–2.9%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Isopropyl myristate~1.6–2.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Butyrospermum parkii butter~1.4–2.1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Ethylhexyl stearate~1.2–1.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Ethylhexyl stearate
Panthenol~0.95–1.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Tocopheryl acetate~0.8–1.2%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Allantoin~0.35–0.85%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationAnti-blemishReduces rednessExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Lavandula angustifolia flower extract~0.45–1%
Irritant · high
Irritation risk
High

Essential oil that can be irritating

More about Lavandula angustifolia flower extract
Prunus amygdalus dulcis oil~0.4–0.9%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil
Argania spinosa kernel oil~0.35–0.8%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties

More about Argania spinosa kernel oil
Parfum~0.15–0.55%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Sodium cetearyl sulfate~0.2–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together and works as a cleansing agent

More about Sodium cetearyl sulfate
Phenoxyethanol~0.1–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Benzyl alcohol~0.05–0.2%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Citric acid~0.01–0.1%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium hydroxide~0.05–0.1%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Ingredient list view

Water, Glycerin, Cetearyl alcohol, Glyceryl stearate, Propylene glycol, Isopropyl myristate, Butyrospermum parkii butter, Ethylhexyl stearate, Panthenol, Tocopheryl acetate, Allantoin, Lavandula angustifolia flower extract, Prunus amygdalus dulcis oil, Argania spinosa kernel oil, Parfum, Sodium cetearyl sulfate, Phenoxyethanol, Benzyl alcohol, Citric acid, Sodium hydroxide

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ISANAHandcreme Night & BeautyYOUR PRODUCTRoC SkincareDermatologic Enydrial Hand CreamNursemCaring Hand Cream Unfragranced CLEARANCENorevaCicadiane Hands Ultra-Nourishing Repairing Cream
Match—66%63%60%
Price—$6.41—$5.29
Shared key ingredients—5 of 63 of 64 of 6
Key difference—Copper GluconateCaprylic/Capric TriglycerideDimethicone
Irritancy Medium Low Low Low
Drying alcohol————
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Product summary

"ISANA - Handcreme Night & Beauty" is effective for: Moisturizing

Ingredient callouts

  • Panthenol (pro-vitamin B5) at about 0.95% - 1.40% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.
  • Humectants (panthenol 0.95% - 1.40% and glycerin 3.70% - 5.50%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 12 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
  3. 3
    Propylene Glycolpubmed.ncbi.nlm.nih.gov
  4. 4
    Skin-sensitizing and irritant properties of propylene glycolonlinelibrary.wiley.com
  5. 5
    Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
  6. 6
    Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
ISANA Handcreme Night & Beauty
ISANAHandcreme Night & Beauty
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