Institut Esthederm Esthe-White System Targeted Dark Spots Concentrate

Institut Esthederm Esthe-White System Targeted Dark Spots Concentrate

Efficacy100/100IrritancyMedium

Works for

Evens skin tone
Acetyl glucosamine, Ascorbyl glucoside + 1 more
Works well
What the product description says
“Esthe-White System Targeted Dark Spots Concentrate”
From product name

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: ascorbyl glucoside, glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~7.6–9.2%
Ascorbyl glucosideKey activeEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~4.5–5.5%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.2–0.35%
Anti-oxidation
Side benefit · Ascorbyl glucoside, Creatine + 5 more
Works well

This product contains antioxidants (carnosine, superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - ascorbyl glucoside, creatine also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Ascorbyl glucosideKey activeEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~4.5–5.5%
CreatineKey activeEffect: MediumCan support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness~0.45–0.7%
CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.15–0.3%
Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.1–0.2%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.2–0.35%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.4–0.65%
Laminaria digitata extractEffect: Low, below effective doseSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.15–0.25%
Moisturizing
Side benefit · Acetyl glucosamine, Peg-12 dimethicone + 7 more
Works well

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": carnosine, saccharide isomerate.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine

Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~7.6–9.2%
Peg-12 dimethiconeKey activeEffect: MediumHelps soften the upper layer of the skin and create a nice product texture~1.9–2.4%
Saccharide isomerateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.2–0.4%
CarnosineKey active· HumectantEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.15–0.3%
Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.1–0.2%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~1.2–1.5%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.55–0.85%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.25–0.5%
Laminaria digitata extractUnder-dosedSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.15–0.25%
Anti-aging
Side benefit · Acetyl glucosamine, Ascorbyl glucoside + 3 more
Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: ascorbyl glucoside, carnosine, creatine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~7.6–9.2%
Ascorbyl glucosideKey activeEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~4.5–5.5%
CreatineKey activeEffect: MediumCan support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness~0.45–0.7%
CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.15–0.3%
Laminaria digitata extractEffect: Low, below effective doseSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.15–0.25%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.3–0.6%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.25–0.5%est.
Ascorbyl glucosideA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in productsMedium~4.5–5.5%est.
Ppg-26-buteth-26Helps oil and water mix togetherMedium~3.2–3.9%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~2.3–2.9%est.
Peg-40 hydrogenated castor oilHelps oil and water mix togetherMedium~1.4–1.7%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~1.2–1.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.55–0.85%est.
Disodium edtaStabilizes the product formulationMedium~0.45–0.65%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.4–0.65%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.2–0.35%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Laminaria digitata extractSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment3/5~0.15–0.25%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Acetyl glucosamine~7.6–9.2%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Ascorbyl glucoside~4.5–5.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-agingAnti-oxidation

A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products

More about Ascorbyl glucoside
Ppg-26-buteth-26~3.2–3.9%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Ppg-26-buteth-26
Citric acid~2.3–2.9%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Peg-12 dimethicone~1.9–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and create a nice product texture

More about Peg-12 dimethicone
Sodium hydroxide~1.6–2%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Peg-40 hydrogenated castor oil~1.4–1.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-40 hydrogenated castor oil
Pentylene glycol~1.2–1.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Xanthan gum~0.9–1.1%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Hexanediol~0.65–0.95%
Formula
Irritation risk
Low

Helps dissolve other ingredients

More about Hexanediol
Caprylyl glycol~0.55–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Creatine~0.45–0.7%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging

Can support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness

More about Creatine
Disodium edta~0.45–0.65%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Parfum~0.3–0.6%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Tocopheryl acetate~0.4–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Disodium phosphate~0.35–0.65%
Formula
Irritation risk
Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate
Propylene glycol~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Potassium phosphate~0.25–0.45%
Formula
Irritation risk
Low

Helps regulate the pH of the formulation

More about Potassium phosphate
Saccharide isomerate~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Saccharide isomerate
Glycyrrhiza glabra root extract~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces rednessEvens skin toneAnti-oxidationAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Carnosine~0.15–0.3%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine
Disodium adenosine triphosphate~0.15–0.3%
Formula
Laminaria digitata extract~0.15–0.25%
Under-dosedComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

Seaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment

More about Laminaria digitata extract
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Superoxide dismutase~0.1–0.2%
Key active
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatory

An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants

More about Superoxide dismutase
Tromethamine~0.05–0.1%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Ingredient list view

Water, Acetyl glucosamine, Ascorbyl glucoside, Ppg-26-buteth-26, Citric acid, Peg-12 dimethicone, Sodium hydroxide, Peg-40 hydrogenated castor oil, Pentylene glycol, Xanthan gum, Hexanediol, Caprylyl glycol, Creatine, Disodium edta, Parfum, Tocopheryl acetate, Disodium phosphate, Propylene glycol, Potassium phosphate, Saccharide isomerate, Glycyrrhiza glabra root extract, Carnosine, Disodium adenosine triphosphate, Laminaria digitata extract, Phenoxyethanol, Superoxide dismutase, Tromethamine

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Institut EsthedermEsthe-White System Targeted Dark Spots ConcentrateYOUR PRODUCTPaula's choice10% Niacinamide BoosterExuvianceAge Reverse Total Correct + Sculpt SerumSwisseVitamin C 5% Niacinamide 5% Brightening Day Cream
Match—58%52%52%
Price—$49.47$89.00$20.46
Shared key ingredients—3 of 62 of 62 of 6
Key difference—NiacinamideAcetyl TyrosinamideNiacinamide
Irritancy Medium Low Low Low
Drying alcohol————
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Product summary

"Institut Esthederm - Esthe-White System Targeted Dark Spots Concentrate" is effective for: Moisturizing, Evens skin tone and Anti-aging

Ingredient callouts

  • Humectants (carnosine 0.15% - 0.30%, saccharide isomerate 0.20% - 0.40% and acetyl glucosamine 7.60% - 9.20%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 50.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 24 studies and safety reviews.

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Institut Esthederm Esthe-White System Targeted Dark Spots Concentrate
Institut EsthedermEsthe-White System Targeted Dark Spots Concentrate

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