Institut Esthederm Esthe-White System Brightening Youth Regenerating Night Care

Institut Esthederm Esthe-White System Brightening Youth Regenerating Night Care

Efficacy100/100IrritancyHigh
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Works for

1 of 1 advertised claim delivered

Evens skin tone
Acetyl glucosamine, Glycyrrhiza glabra root extract + 2 more
Strong evidence
What the product description says
“Institut Esthederm Esthe-White System Brightening Youth Regenerating Night Care 50ml is a care with a soft and creamy texture that intensely plumps the skin and reduces dark spots.”
Source: Cocoon Center

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~1.3–2%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.1–0.3%
Ascorbyl glucosideUnder-dosedEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.15–0.7%
Pisum sativum extractEffect: Low, below effective doseMight be helpful in protecting skin collagen and elastin from breaking down but solid research is lacking~0.1–0.35%
Anti-oxidation
Not advertised by the brand · Carnosine, Superoxide dismutase + 5 more
Strong evidence

This product contains antioxidants (carnosine, superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - creatine also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.05–0.25%
Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.05–0.15%
CreatineKey activeEffect: MediumCan support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness~0.1–0.3%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.1–0.3%
Ascorbyl glucosideUnder-dosedEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.15–0.7%
Laminaria digitata extractEffect: Low, below effective doseSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.05–0.25%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.15–0.65%
Moisturizing
Not advertised by the brand · Acetyl glucosamine, Saccharide isomerate + 13 more
Strong evidence

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: carnosine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, stearyl dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine

Saccharide isomerateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.1–0.35%
Stearyl dimethiconeKey active· EmollientEffect: HighHelps soften the upper layer of the skin~0.15–0.7%
Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.05–0.15%
Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~1.3–2%
CarnosineKey active· HumectantEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.05–0.25%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.2–6.3%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~2.7–4.1%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.4%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.1–0.3%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.45–1.1%
Isononyl isononanoate· Emollient, OcclusiveEffect: LowForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~3.6–5.5%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~1.2–1.7%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.15–0.65%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2–2.9%
Laminaria digitata extractUnder-dosedEffect: MediumSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.05–0.25%
Anti-aging
Not advertised by the brand · Acetyl glucosamine, Carnosine + 3 more
Strong evidence

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: carnosine, creatine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~1.3–2%
CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.05–0.25%
CreatineKey activeEffect: MediumCan support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness~0.1–0.3%
Ascorbyl glucosideUnder-dosedEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.15–0.7%
Laminaria digitata extractEffect: Low, below effective doseSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.05–0.25%

Can it cause trouble?

Irritancy
3 strong irritants: Alcohol denat., Parfum + 1 more — patch-test recommended
High risk
We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~0.3–0.7%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.35%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.1–0.3%est.
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.1–0.35%est.
Ascorbyl glucosideA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in productsMedium~0.15–0.7%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.15–0.65%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.15–0.65%est.
ChlorphenesinA preservativeMedium~0.1–0.3%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.4%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.1–0.3%est.
Pisum sativum extractMight be helpful in protecting skin collagen and elastin from breaking down but solid research is lackingMedium~0.1–0.35%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.1–0.3%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Laminaria digitata extractSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment3/5~0.05–0.25%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.2–6.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Isononyl isononanoate~3.6–5.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Squalane~2.7–4.1%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Butylene glycol~2–2.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Propanediol~1.6–2.4%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Acetyl glucosamine~1.3–2%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Octyldodecanol~1.2–1.7%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Hdi/trimethylol hexyllactone crosspolymer~0.95–1.4%
Formula
Irritation risk
Low

Used to create a silky product texture and add volume to products

More about Hdi/trimethylol hexyllactone crosspolymer
Glycol palmitate~0.6–1.35%
Formula
Irritation risk
Low
Works for
Cleansing
More about Glycol palmitate
Glyceryl stearate~0.45–1.1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~0.4–0.95%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Alcohol denat.~0.3–0.7%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Ascorbyl glucoside~0.15–0.7%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-agingEvens skin tone

A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products

More about Ascorbyl glucoside
Tocopheryl acetate~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Stearyl dimethicone~0.15–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Stearyl dimethicone
Ammonium acryloyldimethyltaurate/vp copolymer~0.15–0.6%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Pentylene glycol~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Sorbitan stearate~0.15–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan stearate
Carbomer~0.1–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Parfum~0.1–0.35%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Sodium hydroxide~0.1–0.4%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Chlorphenesin~0.1–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Hexanediol~0.1–0.35%
Formula
Irritation risk
Low

Helps dissolve other ingredients

More about Hexanediol
Caprylyl glycol~0.1–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Octadecene~0.1–0.35%
Formula
Irritation risk
Low
More about Octadecene
Sodium citrate~0.1–0.3%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Creatine~0.1–0.3%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging

Can support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness

More about Creatine
Potassium phosphate~0.1–0.35%
Formula
Irritation risk
Low

Helps regulate the pH of the formulation

More about Potassium phosphate
Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.1–0.35%
Formula
Irritation risk
Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate
Pisum sativum extract~0.1–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Evens skin tone

Might be helpful in protecting skin collagen and elastin from breaking down but solid research is lacking

More about Pisum sativum extract
Propylene glycol~0.1–0.3%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Phenoxyethanol~0.1–0.35%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Silica~0.15–0.55%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
Alcohol~0.1–0.35%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Saccharide isomerate~0.1–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Saccharide isomerate
Disodium phosphate~0.1–0.35%
Formula
Irritation risk
Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate
Glycyrrhiza glabra root extract~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces rednessEvens skin toneAnti-oxidationAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Tris(tetramethylhydroxypiperidinol) citrate~0.05–0.3%
Formula
Carnosine~0.05–0.25%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine
Disodium adenosine triphosphate~0.05–0.25%
Formula
Laminaria digitata extract~0.05–0.25%
Under-dosedComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

Seaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment

More about Laminaria digitata extract
Superoxide dismutase~0.05–0.15%
Key active
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatory

An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants

More about Superoxide dismutase
Tromethamine~0.05–0.1%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Ingredient list view

Water, Glycerin, Isononyl isononanoate, Squalane, Butylene glycol, Propanediol, Acetyl glucosamine, Octyldodecanol, Hdi/trimethylol hexyllactone crosspolymer, Glycol palmitate, Glyceryl stearate, Peg-100 stearate, Alcohol denat., Ascorbyl glucoside, Tocopheryl acetate, Stearyl dimethicone, Ammonium acryloyldimethyltaurate/vp copolymer, Pentylene glycol, Sorbitan stearate, Carbomer, Parfum, Sodium hydroxide, Chlorphenesin, Hexanediol, Caprylyl glycol, Octadecene, Sodium citrate, Creatine, Potassium phosphate, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Pisum sativum extract, Propylene glycol, Phenoxyethanol, Silica, Alcohol, Saccharide isomerate, Disodium phosphate, Glycyrrhiza glabra root extract, Tris(tetramethylhydroxypiperidinol) citrate, Carnosine, Disodium adenosine triphosphate, Laminaria digitata extract, Superoxide dismutase, Tromethamine

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Institut EsthedermEsthe-White System Brightening Youth Regenerating Night CareYOUR PRODUCTEstée LauderRevitalizing Supreme+ Bright Power Soft Milky LotionMedik8ADVANCED PRO COLLAGEN+ PEPTIDE CREAMLab Series Skincare for MenAnti-Age Max Cream
Match—57%55%55%
Price$122.05$85.00−$37.05$99.00−$23.05$84.15−$37.90
Shared key ingredients—3 of 94 of 93 of 9
Key difference—Acetyl Hexapeptide-8Oligopeptide-1Niacinamide
Irritancy High Medium Medium Medium
Drying alcohol Contains drying alcohol ———
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Product summary

"Institut Esthederm - Esthe-White System Brightening Youth Regenerating Night Care" is a well-rounded moisturizing product. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (acetyl glucosamine, carnosine, glycerin, saccharide isomerate and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Stearyl dimethicone, squalane, caprylyl glycol, glyceryl stearate and octyldodecanol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Irritation risk

We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 91.30£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 25 studies and safety reviews.

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Institut Esthederm Esthe-White System Brightening Youth Regenerating Night Care
Institut EsthedermEsthe-White System Brightening Youth Regenerating Night Care

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