Works for
Anti-agingAcetyl hexapeptide-8, Adenosine + 5 moreWorks well
“Gracefully age with the help of this highly concentrated ampoule formulated with eight types of peptides to smooth skin texture, enhance skin elasticity and improve the appearance of fine lines.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, copper tripeptide-1, nicotinoyl tripeptide-1, palmitoyl pentapeptide-4, sh-octapeptide-4, sh-pentapeptide-19.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
MoisturizingAcetyl hexapeptide-8, Sh-octapeptide-4 + 14 moreWorks well
“The gentle formula also hydrates skin for soft and supple skin.”
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": betaine, glycerin.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, palmitoyl pentapeptide-4, sh-octapeptide-4, sh-pentapeptide-19
Can it cause trouble?
Irritancy9 flagged ingredients — patch-test recommendedHigh risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~40–60%
Butylene glycol~4.5–6.7%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolGlycerin~2.7–4%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about Glycerin1,2-hexanediol~1.7–2.6%
Acetyl hexapeptide-8~1.5–2.3%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Caprylyl glycol~1.2–1.8%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolGlycosyl trehalose~1.1–1.7%
Hydrogenated starch hydrolysate~1.1–1.6%
- Irritation risk
- Low
Helps to attract water to the upper layer of the skin. Can add sweet taste to lip products
More about Hydrogenated starch hydrolysateBetaine~0.8–1.2%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and improves the product texture
More about BetaineAllantoin~0.35–0.8%
- Irritation risk
- Low
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
More about AllantoinCarbomer~0.2–0.75%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerPolyglyceryl-4 caprate~0.15–0.6%
Tromethamine~0.1–0.3%
Adenosine~0.05–0.2%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineEthylhexylglycerin~0.05–0.25%
Dipotassium glycyrrhizate~0.05–0.2%
- Irritation risk
- Low
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
More about Dipotassium glycyrrhizatePentylene glycol~0.1–0.3%
- Irritation risk
- Medium
Used to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolLavandula angustifolia oil~0.05–0.2%
- Irritation risk
- High
An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties
More about Lavandula angustifolia oilAspalathus linearis extract~0.05–0.2%
- Irritation risk
- Low
Glycyrrhiza glabra root extract~0.05–0.1%
- Irritation risk
- Medium
A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals
More about Glycyrrhiza glabra root extractCommiphora myrrha resin extract~0.01–0.1%
- Irritation risk
- High
Used as a fragrance. Can be irritating
More about Commiphora myrrha resin extractPerilla frutescens leaf extract~0.01–0.1%
- Irritation risk
- High
Used as a fragrance for its mint-like smell
More about Perilla frutescens leaf extractYucca schidigera root extract~0.01–0.05%
- Irritation risk
- Low
Copper tripeptide-1~0.01–0.05%
- Irritation risk
- Low
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
More about Copper tripeptide-1Nicotinoyl tripeptide-1~0.01–0.05%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Nicotinoyl tripeptide-1Palmitoyl pentapeptide-4~0.01–0.05%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl pentapeptide-4Caffeoyl sh-octapeptide-4~0.01–0.05%
- Irritation risk
- Low
Caffeoyl tripeptide-1~0.05–0.1%
- Irritation risk
- Low
Sh-octapeptide-4~0.05–0.15%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Sh-octapeptide-4Sh-decapeptide-9~0.05–0.15%
- Irritation risk
- Low
Sh-pentapeptide-19~0.01–0.1%
Linalool~0.01–0.05%
Ingredient list view
Water, Butylene glycol, Glycerin, 1,2-hexanediol, Acetyl hexapeptide-8, Caprylyl glycol, Glycosyl trehalose, Hydrogenated starch hydrolysate, Betaine, Allantoin, Carbomer, Polyglyceryl-4 caprate, Tromethamine, Adenosine, Ethylhexylglycerin, Dipotassium glycyrrhizate, Pentylene glycol, Lavandula angustifolia oil, Aspalathus linearis extract, Glycyrrhiza glabra root extract, Commiphora myrrha resin extract, Perilla frutescens leaf extract, Yucca schidigera root extract, Copper tripeptide-1, Nicotinoyl tripeptide-1, Palmitoyl pentapeptide-4, Caffeoyl sh-octapeptide-4, Caffeoyl tripeptide-1, Sh-octapeptide-4, Sh-decapeptide-9, Sh-pentapeptide-19, Linalool
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| GRAYMELINMulti Peptide AmpouleYOUR PRODUCT | SUNGBOON EDITORSilk Peptide EGF Intensive Ampoule | HanskinCollagen Peptide Hydra Ampoule | EqqualberryNAD+ Peptide Boosting Serum | |
|---|---|---|---|---|
| Match | — | 61% | 56% | 53% |
| Price | $16.50 | $23.02+$6.52 | $22.39+$5.89 | $17.83+$1.33 |
| Shared key ingredients | — | 8 of 11 | 8 of 11 | 6 of 11 |
| Key difference | — | Sh-Decapeptide-7 | Pentapeptide-18 | Acetyl Tetrapeptide-3 |
| Irritancy | High | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Holika Holika Prime Youth 24K Gold Repair AmpouleNatureONE Volufiline Peptide Ampoule
Product summary
"GRAYMELIN - Multi Peptide Ampoule" is effective for: Anti-aging and Moisturizing
Ingredient callouts
- Peptides (sh-pentapeptide-19 0.01% - 0.10%, sh-octapeptide-4 0.05% - 0.15%, palmitoyl pentapeptide-4 0.01% - 0.05%, copper tripeptide-1 0.01% - 0.05% and acetyl hexapeptide-8 1.50% - 2.30%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Adenosine 0.05% - 0.20%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
- Humectants (glycerin 2.70% - 4.00%, betaine 0.80% - 1.20% and acetyl hexapeptide-8 1.50% - 2.30%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 16.50$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 12 studies and safety reviews.
- 1
- 2
- 3Safety assessment of hydrogenated starch hydrolysatesncbi.nlm.nih.gov
- 4
- 5Safety Assessment of Tromethamine as Used in Cosmeticscir-safety.org
- 6
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