GlyMed Plus

GlyMed Plus Bio Renewal Peptide Serum

Name: GlyMed Plus - Bio Renewal Peptide Serum
Brand: GlyMed Plus

Efficacy100/100IrritancyHigh·

See all ingredients

Works for

Moisturizing

Acetyl hexapeptide-8, Palmitoyl tripeptide-1 + 17 more

Works well

What the product description says

“Refine skins texture and increase hydration”

Source: GlyMed Plus

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, glycine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: vitis vinifera seed oil, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, hexanoyl dipeptide-3 norleucine acetate, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, panthenol

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~7.7–9.4%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.5–1.8%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.3–1.6%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.95–1.2%

Hexanoyl dipeptide-3 norleucine acetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.7–1.05%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.6–0.9%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~1.8–2.2%

GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.5–0.75%

Hydrolyzed soy proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.35–0.6%

Vitis vinifera seed oilKey active· EmollientEffect: HighA great emollient that can also have anti-oxidant properties~0.25–0.45%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~2.2–2.7%

Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.45–0.65%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.3–0.6%

Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.5%

Moringa oleifera seed oil· EmollientEffect: LowA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid~0.2–0.4%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.4%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.45%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%

Anti-oxidation

Side benefit · Camellia sinensis leaf extract, Vitis vinifera seed extract + 5 more

Works well

This product contains antioxidants (vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - camellia sinensis leaf extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.5%

Vitis vinifera seed extractKey activeEffect: HighA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.25–0.5%

Hydrolyzed soy proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.35–0.6%

Vitis vinifera seed oilEffect: LowA great emollient that can also have anti-oxidant properties~0.25–0.45%

Olea europaea leaf extractEffect: LowA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing~0.2–0.35%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%

Tetrahexyldecyl ascorbateUnder-dosedBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.2–0.4%

Anti-aging

Side benefit the brand mentions · Acetyl hexapeptide-8, Palmitoyl tripeptide-1 + 7 more

May help

What the product description says

“This lightweight serum contains an exclusive tri-peptide complex, which naturally revitalizes the critical exfoliation process that occurs in youthful skin.”

Source: N/A

This product contains acetyl hexapeptide-8, copper tripeptide-1, hexanoyl dipeptide-3 norleucine acetate, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, vitis vinifera seed extract. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~7.7–9.4%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.5–1.8%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.3–1.6%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.95–1.2%

Hexanoyl dipeptide-3 norleucine acetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.7–1.05%

Vitis vinifera seed extractKey activeEffect: MediumA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.25–0.5%

Can it cause trouble?

Irritancy

3 strong irritants: Carica papaya fruit extract, Citrus limon peel oil + 1 more — patch-test recommended

High risk

We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Carica papaya fruit extract—High~0.2–0.4%est.

Citrus limon peel oilA highly irritating fragranceHigh~0.2–0.35%est.

Citrus aurantifolia peel oil—High~0.2–0.4%est.

Ci 19140A yellow dyeHigh~0.05%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~2.2–2.7%est.

Olea europaea leaf extractA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missingMedium~0.2–0.35%est.

Moringa oleifera seed oilA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acidMedium~0.2–0.4%est.

Vitis vinifera seed oilA great emollient that can also have anti-oxidant propertiesMedium~0.25–0.45%est.

Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Medium~0.2–0.4%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.4%est.

Hexylene glycolHelps create a more spreadable product textureMedium~0.15–0.3%est.

EthylhexylglycerinA preservativeMedium~0.15–0.25%est.

Ci 42090A colorant (dye)Medium~0.05–0.1%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

Alternatives

The closest match we found

Arencia Deep Water Surge Serum

Closest match58% match

$32.63

View all alternatives

User reviews

Would you recommend?

100%·yes

1 of 1 community members would buy it again.

100% would0% wouldn't

skinticians· Aug 2022Recommends
gives a luminous glow and makes me happy. My skin feels smoother.
Moisturization
Excellent
Texture
Light
Pilling under makeup
Not at all
Clogging pores
Doesn't clog pores
Smell
Light fragrance

What reviewers noticed

Marker shows the average response

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Acetyl hexapeptide-8~7.7–9.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Glycerin~4–4.9%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Polysorbate 20~2.6–3.2%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Pentylene glycol~2.2–2.7%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Sodium hyaluronate~1.8–2.2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Palmitoyl tripeptide-1~1.5–1.8%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Palmitoyl tetrapeptide-7~1.3–1.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Copper tripeptide-1~0.95–1.2%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Hexanoyl dipeptide-3 norleucine acetate~0.7–1.05%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexanoyl dipeptide-3 norleucine acetate

Panthenol~0.6–0.9%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Glycine~0.5–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine

Sorbitol~0.45–0.65%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol

Dimethyl mea~0.4–0.6%

Formula

Irritation risk: Low

More about Dimethyl mea

Hydrolyzed soy protein~0.35–0.6%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-inflammatoryEvens skin tone

Helps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing

More about Hydrolyzed soy protein

Propanediol~0.35–0.65%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Butylene glycol~0.3–0.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Mucor miehei extract~0.3–0.55%

Formula

Irritation risk: Low

More about Mucor miehei extract

Camellia sinensis leaf extract~0.3–0.5%

Key active

Irritation risk: Low

Works for

Anti-oxidationAntibacterialAnti-agingMoisturizingEvens skin toneAnti-blemish

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Vitis vinifera seed extract~0.25–0.5%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryAntibacterial

A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation

More about Vitis vinifera seed extract

Olea europaea leaf extract~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing

More about Olea europaea leaf extract

Carica papaya fruit extract~0.2–0.4%

Irritant · high

Irritation risk: High

More about Carica papaya fruit extract

Citrus limon peel oil~0.2–0.35%

Irritant · high

Irritation risk: High

A highly irritating fragrance

More about Citrus limon peel oil

Moringa oleifera seed oil~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid

More about Moringa oleifera seed oil

Vitis vinifera seed oil~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

A great emollient that can also have anti-oxidant properties

More about Vitis vinifera seed oil

Citrus aurantifolia peel oil~0.2–0.4%

Irritant · high

Irritation risk: High

More about Citrus aurantifolia peel oil

Tocopherol~0.2–0.35%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Tetrahexyldecyl ascorbate~0.2–0.4%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneAnti-agingAnti-oxidation

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

More about Tetrahexyldecyl ascorbate

Lecithin~0.25–0.45%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Carbomer~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Caprylyl glycol~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Hexylene glycol~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol

Phenoxyethanol~0.15–0.3%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Ethylhexylglycerin~0.15–0.25%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Sodium hydroxide~0.15–0.25%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Mica~0.15–0.25%

Formula

Irritation risk: Low

Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light

More about Mica

Titanium dioxide~0.1–0.2%

Formula

Irritation risk: Low

Works for

Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide

Ci 42090~0.05–0.1%

Irritant · medium

Irritation risk: Medium

A colorant (dye)

More about Ci 42090

Ci 19140~0.05%

Irritant · high

Irritation risk: High

A yellow dye

More about Ci 19140

Ingredient list view

Water, Acetyl hexapeptide-8, Glycerin, Polysorbate 20, Pentylene glycol, Sodium hyaluronate, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Copper tripeptide-1, Hexanoyl dipeptide-3 norleucine acetate, Panthenol, Glycine, Sorbitol, Dimethyl mea, Hydrolyzed soy protein, Propanediol, Butylene glycol, Mucor miehei extract, Camellia sinensis leaf extract, Vitis vinifera seed extract, Olea europaea leaf extract, Carica papaya fruit extract, Citrus limon peel oil, Moringa oleifera seed oil, Vitis vinifera seed oil, Citrus aurantifolia peel oil, Tocopherol, Tetrahexyldecyl ascorbate, Lecithin, Carbomer, Caprylyl glycol, Hexylene glycol, Phenoxyethanol, Ethylhexylglycerin, Sodium hydroxide, Mica, Titanium dioxide, Ci 42090, Ci 19140

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	GlyMed PlusBio Renewal Peptide SerumYOUR PRODUCT	ArenciaDeep Water Surge Serum	MedicubeHyaluronic Multi Peptide Serum	MatkasHyaluronic Acid Firming Boost Serum
Match	—	58%	57%	57%
Price	—	$32.63	$18.90	$25.97
Shared key ingredients	—	8 of 13	7 of 13	7 of 13
Key difference	—	Hexapeptide-9	Tripeptide-1	Hexapeptide-9
Irritancy	High	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop