GlyDerm Cream Plus 12

GlyDerm Cream Plus 12

Efficacy90/100IrritancyMedium
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Works for

4 of 5 advertised claims delivered

Exfoliation
2 ingredients credited for this claim
Strong support
What the product description says
“An intensive complex of 12% glycolic acid and salicylic acid exfoliate dead skin to diminish fine lines, wrinkles and hyperpigmentation while promoting firmness and an even tone.”
Source: Dermstore

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~5.8–8.7%
Salicylic acidUnder-dosedEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.15–0.5%
Moisturizing
5 ingredients credited for this claim
Strong support
What the product description says
“Cream Plus 12”
From product name

This product can help soften the skin and reduce its moisture loss with emollients and occlusives: paraffinum liquidum, petrolatum.

Keep in mind that this product does not contain effective ingredients to attract water to the upper layer of the skin. This is why an additional product with humectants like glycerin or hyaluronic acid can be helpful (apply it before this product for the best results).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: paraffinum liquidum, petrolatum

Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~2.7–4.1%
PetrolatumHero· Emollient, OcclusiveEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~2.1–3.1%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~3.2–4.8%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.9–1.35%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.95–1.45%
Evens skin tone
2 ingredients credited for this claim
Strong support
What the product description says
“An intensive complex of 12% glycolic acid and salicylic acid exfoliate dead skin to diminish fine lines, wrinkles and hyperpigmentation while promoting firmness and an even tone.”
Source: Dermstore

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glycolic acid

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~5.8–8.7%
Salicylic acidEffect: Low, below effective doseUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.15–0.5%
Anti-aging
1 ingredient credited for this claim
Strong support
What the product description says
“An intensive complex of 12% glycolic acid and salicylic acid exfoliate dead skin to diminish fine lines, wrinkles and hyperpigmentation while promoting firmness and an even tone.”
Source: Dermstore

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains glycolic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~5.8–8.7%
Anti-blemish
2 ingredients credited for this claim
Limited support
What the product description says
“Naturally astringent lemon extract minimizes the pores and supports a radiant complexion.”
Source: Dermstore

This product contains ingredients (glycolic acid) that could help reduce blemishes and clogged pores in theory, but there is not enough evidence that they actually work.

Glycolic acidKey activeEffect: MediumAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~5.8–8.7%
Salicylic acidUnder-dosedEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.15–0.5%

Can it cause trouble?

Irritancy
2 strong irritants: Citrus limon fruit extract, Imidazolidinyl urea
Medium risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~5.8–8.7%est.
Sodium lauryl sulfateA cleansing agent (SLS). It can be irritatingHigh~1.6–2.4%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.95–1.45%est.
Citrus limon fruit extractUsed as a fragrance. Can be irritating and cause photosensitivityHigh~0.4–0.9%est.
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~0.15–0.5%est.
Imidazolidinyl ureaA preservative. Is more irritating than many other preservatives availableHigh~0.1–0.35%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~0.9–1.35%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Sodium lauryl sulfateA cleansing agent (SLS). It can be irritating3/5~1.6–2.4%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.9–1.35%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~3.2–4.8%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycolic acid~5.8–8.7%
Key activeIrritant · high
Irritation risk
High
Works for
ExfoliationAnti-agingEvens skin toneAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid
Cetearyl alcohol~3.2–4.8%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Paraffinum liquidum~2.7–4.1%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Petrolatum~2.1–3.1%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Sodium lauryl sulfate~1.6–2.4%
Comedogenic 3/5Irritant · high
Irritation risk
High
Comedogenicity
3/5
Works for
Cleansing

A cleansing agent (SLS). It can be irritating

More about Sodium lauryl sulfate
Propylene glycol~0.95–1.45%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Isopropyl palmitate~0.9–1.35%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Citrus limon fruit extract~0.4–0.9%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating and cause photosensitivity

More about Citrus limon fruit extract
Salicylic acid~0.15–0.5%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-inflammatoryExfoliationAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Imidazolidinyl urea~0.1–0.35%
Irritant · high
Irritation risk
High

A preservative. Is more irritating than many other preservatives available

More about Imidazolidinyl urea
Methylparaben~0.05–0.2%
Formula
Irritation risk
Low

A preservative

More about Methylparaben
Propylparaben~0.05–0.15%
Formula
Irritation risk
Low

A preservative

More about Propylparaben
Ingredient list view

Water, Glycolic acid, Cetearyl alcohol, Paraffinum liquidum, Petrolatum, Sodium lauryl sulfate, Propylene glycol, Isopropyl palmitate, Citrus limon fruit extract, Salicylic acid, Imidazolidinyl urea, Methylparaben, Propylparaben

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Dermstore
$46.50
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
GlyDermCream Plus 12YOUR PRODUCTAvèneCicalfate CreamElizabeth ArdenEight Hour Cream Skin Protectant Fragrance FreeCliniqueiD™: Dramatically Different Moisturizing Lotion™ + ACC for Fatigue
Match—88%88%80%
Price$46.50$19.82−$26.68$19.20−$27.30$41.00−$5.50
Shared key ingredients—1 of 43 of 44 of 4
Key difference—BeeswaxLanolinUrea
Irritancy Medium Low Low Medium
Drying alcohol————
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Product summary

"GlyDerm - Cream Plus 12" is effective for: Anti-inflammatory, Exfoliation, Moisturizing, Evens skin tone and Anti-aging

Ingredient callouts

  • Exfoliating acids (glycolic acid 5.80% - 8.70%). In this concentration, they will have a noticeable exfoliating effect. They can also have an anti-aging effect and stimulate collagen production in a long-run.

Price

The product retails for 46.50$ in the United States.

For a detailed price comparison: click here.

GlyDerm Cream Plus 12
GlyDermCream Plus 12

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