Eucerin Hyaluron-Filler Epigenetic Serum

Eucerin Hyaluron-Filler Epigenetic Serum

Efficacy75/100IrritancyMedium

Works for

Evens skin tone
Glycyrrhetinic acid, Dihydromyricetin
May help

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: dihydromyricetin, glycyrrhetinic acid.

Glycyrrhetinic acidKey activeEffect: MediumActive compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation~0.45–0.7%
DihydromyricetinEffect: LowAntioxidant that could help even skin tone by suppressing melanin production and might have anti‑aging benefits, even though the evidence for effectiveness in skincare formulations is not yet strong~0.05–0.15%
Anti-aging
Dihydromyricetin, Tocopherol
May help
What the product description says
“After 15 years of epigenetic research, Eucerin has harnessed the latest advancements in epigenetic science and discovered how to reactivate these youth genes based on a patented Age Clock Technology Epicelline® reactivates the skin’s youth genes at the root and allows skin cells to act younger, promoting a youthful and revitalised complexion.”
Source: N/A

This product contains glycyrrhetinic acid. This ingredient help neutralize free radicals in skin. By doing so, they might be able to prevent early signs of aging (like fine lines and wrinkles), at least to some extent. These ingredients will not be able to "reverse" signs of aging.

DihydromyricetinEffect: LowAntioxidant that could help even skin tone by suppressing melanin production and might have anti‑aging benefits, even though the evidence for effectiveness in skincare formulations is not yet strong~0.05–0.15%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.65%
Moisturizing
Glycerin, Ricinus communis seed oil + 12 more
Works
What the product description says
“This powerful serum gives a boost of hydration to help even and smooth out the skin, leaving your skin feeling radiant and rejuvenated at a cellular level, allowing you to enjoy a visibly younger and healthier complexion.”
Source: N/A

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: ricinus communis seed oil, cetearyl alcohol.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3–3.7%
Ricinus communis seed oilKey active· Emollient, OcclusiveEffect: HighA plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency~2.4–3%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.2–1.5%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.65–0.95%
Propylheptyl caprylateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.45–0.65%
Lauroyl lysineKey activeEffect: MediumHelps soften the upper layer of the skin and creates a nice product texture~0.25–0.5%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~4.1–5%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~1.8–2.2%
Dibutyl adipate· EmollientEffect: LowHelps soften the upper layer of the skin and create a nice product consistency~1.7–2.1%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~1.4–1.7%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.35–0.65%
SuccinoglycanEffect: Low~0.05–0.1%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.65%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.45–0.7%
Anti-oxidation
Not advertised by the brand · Glycyrrhetinic acid, Tocopherol
Works well

This product contains antioxidants (glycyrrhetinic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Glycyrrhetinic acidKey activeEffect: HighActive compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation~0.45–0.7%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.65%

Can it cause trouble?

Irritancy
2 strong irritants: Alcohol denat., Parfum
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~7.7–9.4%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.2%est.
Ricinus communis seed oilA plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistencyMedium~2.4–3%est.
Glycyrrhetinic acidActive compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentationMedium~0.45–0.7%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.45–0.7%est.
Succinoglycan—Medium~0.25–0.5%est.
Diethylhexyl syringylidenemalonateUsed to stabilize the product formulationMedium~0.2–0.4%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.4%est.
Trisodium ethylenediamine disuccinateUsed to improve stability of the formulationMedium~0.2–0.35%est.
EthylhexylglycerinA preservativeMedium~0.2–0.35%est.
Sodium metabisulfiteA preservativeMedium~0.1–0.2%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.2–1.5%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Alcohol denat.~7.7–9.4%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Butylene glycol~4.1–5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Glycerin~3–3.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Ricinus communis seed oil~2.4–3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-inflammatory

A plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency

More about Ricinus communis seed oil
Octyldodecanol~1.8–2.2%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Dibutyl adipate~1.7–2.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and create a nice product consistency

More about Dibutyl adipate
Glyceryl stearate citrate~1.4–1.7%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Cetearyl alcohol~1.2–1.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Dihydromyricetin~0.8–1.2%
Formula
Irritation risk
Low
Works for
Evens skin toneAnti-agingAnti-inflammatory

Antioxidant that could help even skin tone by suppressing melanin production and might have anti‑aging benefits, even though the evidence for effectiveness in skincare formulations is not yet strong

More about Dihydromyricetin
Sodium hyaluronate~0.65–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Glycine soja germ extract~0.55–0.85%
Formula
Glycyrrhetinic acid~0.45–0.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryAnti-oxidationEvens skin tone

Active compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation

More about Glycyrrhetinic acid
Tocopherol~0.45–0.65%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingMoisturizingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Propylheptyl caprylate~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Propylheptyl caprylate
Caprylic/capric triglyceride~0.45–0.7%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Distarch phosphate~0.35–0.6%
Formula
Glyceryl stearate~0.35–0.65%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Lauroyl lysine~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and creates a nice product texture

More about Lauroyl lysine
Succinoglycan~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing
More about Succinoglycan
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Gellan gum~0.25–0.45%
Formula
Irritation risk
Low

Used to improve the product texture

More about Gellan gum
Diethylhexyl syringylidenemalonate~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Used to stabilize the product formulation

More about Diethylhexyl syringylidenemalonate
Citric acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Trisodium ethylenediamine disuccinate~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Used to improve stability of the formulation

More about Trisodium ethylenediamine disuccinate
Sodium hydroxide~0.2–0.35%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Ethylhexylglycerin~0.2–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Sodium metabisulfite~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sodium metabisulfite
Phenoxyethanol~0.1–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Parfum~0.1–0.2%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Dihydromyricetin~0.05–0.15%
Formula
Irritation risk
Low
Works for
Evens skin toneAnti-inflammatoryAnti-aging

Antioxidant that could help even skin tone by suppressing melanin production and might have anti‑aging benefits, even though the evidence for effectiveness in skincare formulations is not yet strong

More about Dihydromyricetin
Succinoglycan~0.05–0.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing
More about Succinoglycan
Ingredient list view

Water, Alcohol denat., Butylene glycol, Glycerin, Ricinus communis seed oil, Octyldodecanol, Dibutyl adipate, Glyceryl stearate citrate, Cetearyl alcohol, Dihydromyricetin, Sodium hyaluronate, Glycine soja germ extract, Glycyrrhetinic acid, Tocopherol, Propylheptyl caprylate, Caprylic/capric triglyceride, Distarch phosphate, Glyceryl stearate, Lauroyl lysine, Succinoglycan, Xanthan gum, Gellan gum, Diethylhexyl syringylidenemalonate, Citric acid, Trisodium ethylenediamine disuccinate, Sodium hydroxide, Ethylhexylglycerin, Sodium metabisulfite, Phenoxyethanol, Parfum, Dihydromyricetin, Succinoglycan

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🇬🇧 Amazon UK (UK)Price as of 11/1 03:53 GMT
≈ $42.82
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
EucerinHyaluron-Filler Epigenetic SerumYOUR PRODUCTPeter Thomas RothWater Drench Hyaluronic Glow SerumDr. Barbara SturmThe Good C Vitamin C SerumNIP+FABHyaluronic Fix Extreme4 2% Hydration Serum
Match—43%41%41%
Price—$50.12$139.76$24.60
Shared key ingredients—4 of 64 of 64 of 6
Key difference—Lactic AcidPanthenolPolyglutamic Acid
Irritancy Medium Low Low Low
Drying alcohol Contains drying alcohol ———
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Product summary

"Eucerin - Hyaluron-Filler Epigenetic Serum" could be helpful for: Evens skin tone, Anti-aging and Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Humectants (sodium hyaluronate 0.65% - 0.95% and glycerin 3.00% - 3.70%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 13 studies and safety reviews.

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  5. 5
  6. 6
Eucerin Hyaluron-Filler Epigenetic Serum
EucerinHyaluron-Filler Epigenetic Serum

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As an Amazon Associate, WIMJ earns from qualifying purchases.