Estée Lauder Perfectly Clean Infusion Balancing Essence Lotion with Amino Acid and Waterlily

Estée Lauder Perfectly Clean Infusion Balancing Essence Lotion with Amino Acid and Waterlily

Efficacy50/100IrritancyMedium
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Works for

1 of 2 advertised claims delivered

Moisturizing
Urea, Aspartic acid + 22 more
Strong evidence
What the product description says
“Boosted with Amino Acid 15 Complex and hydration powerhouse Waterlily Flower Extract to help amplify moisturization within skin's surface.”
Source: Bluemercury

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, arginine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: urea

Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.55–0.85%
ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.45–0.7%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~1.8–2.2%
TyrosineKey activeEffect: High~0.3–0.55%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.3–0.5%
AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.45–0.7%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.5–0.75%
Dipotassium glycyrrhizateKey active· HumectantEffect: HighA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~1.5–1.9%
Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.65–1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.6%
GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.25–0.5%
HistidineKey active· HumectantEffect: High~0.4–0.6%
IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.35–0.6%
LysineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.5–0.7%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.45–0.65%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~2.2–2.7%
Sodium pcaKey active· HumectantEffect: HighNaturally present in skin and helps to attract water to its upper layer~0.3–0.5%
SucroseKey active· HumectantEffect: HighCan help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion~0.25–0.5%
Hypnea musciformis extractKey active· HumectantEffect: MediumMight help to attract water to the upper layer of the skin~0.3–0.5%
ProlineKey activeEffect: Medium~0.9–1.15%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.55%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~5.2–6.3%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.3–0.5%
Polyquaternium-51Effect: LowAn emollient that helps create a nice silky finish on the skin~0.2–0.35%
Anti-blemish
No ingredient credited for this claim
No evidence
What the product description says
“Restore and balance skin in one simple step.”
Source: Bluemercury

Effective ingredients missing or their concentration is too low.

Anti-aging
Not advertised by the brand · Threonine, Aspartic acid + 2 more
Moderate evidence

This product contains aspartic acid, lysine, serine, threonine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.45–0.7%
Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.55–0.85%
LysineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.5–0.7%
SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.45–0.65%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
TriacetinUsed to dissolve other ingredientsHigh~0.25–0.45%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.2%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~5.2–6.3%est.
CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~1.3–1.6%est.
Nymphaea alba root extractA plant root extract that might help neutralize free radicals in skinMedium~0.25–0.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.55%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.3–0.5%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.25–0.45%est.
Ppg-5-ceteth-20A solvent with some emollient propertiesMedium~0.25–0.45%est.
ChlorphenesinA preservativeMedium~0.15–0.3%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.1–0.2%est.
Disodium edtaStabilizes the product formulationMedium~0.1–0.2%est.
Potassium sorbateA preservativeMedium~0.1–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Hypnea musciformis extractMight help to attract water to the upper layer of the skin3/5~0.3–0.5%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Pentylene glycol~5.2–6.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Polysorbate 20~3.7–4.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Nymphaea alba flower extract~3–3.7%
Formula
Sodium hyaluronate~2.2–2.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Trehalose~1.8–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Dipotassium glycyrrhizate~1.5–1.9%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Caffeine~1.3–1.6%
Irritant · medium
Irritation risk
Medium
Works for
De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine
Phenylalanine~1.1–1.4%
Formula
Irritation risk
Low
More about Phenylalanine
Proline~0.9–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Proline
Glutamic acid~0.65–1%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid
Aspartic acid~0.55–0.85%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid
Arginine~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Lysine~0.5–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Lysine
Serine~0.45–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Alanine~0.45–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Threonine~0.45–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine
Histidine~0.4–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Histidine
Isoleucine~0.35–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine
Tyrosine~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Tyrosine
Leucine~0.3–0.55%
Formula
Irritation risk
Low
More about Leucine
Valine~0.3–0.55%
Formula
Irritation risk
Low
More about Valine
Glycine~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine
Nymphaea alba root extract~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant root extract that might help neutralize free radicals in skin

More about Nymphaea alba root extract
Berberis vulgaris root extract~0.3–0.55%
Formula
Polygala senega root extract~0.3–0.5%
Formula
Hypnea musciformis extract~0.3–0.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Might help to attract water to the upper layer of the skin

More about Hypnea musciformis extract
Sucrose~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Can help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion

More about Sucrose
Sodium pca~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca
Urea~0.3–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Glycerin~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Caprylyl glycol~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Butylene glycol~0.3–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Jojoba wax peg-120 esters~0.3–0.5%
Formula
Irritation risk
Low
Works for
Cleansing
More about Jojoba wax peg-120 esters
Citric acid~0.3–0.5%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Dipropylene glycol~0.25–0.45%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Hexylene glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Sodium hydroxide~0.25–0.45%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Triacetin~0.25–0.45%
Irritant · high
Irritation risk
High

Used to dissolve other ingredients

More about Triacetin
Sodium palmitoyl proline~0.2–0.4%
Formula
Ppg-5-ceteth-20~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

A solvent with some emollient properties

More about Ppg-5-ceteth-20
Chlorphenesin~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Polyquaternium-51~0.2–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps create a nice silky finish on the skin

More about Polyquaternium-51
Parfum~0.1–0.2%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Sodium citrate~0.1–0.2%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Disodium edta~0.1–0.2%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Potassium sorbate~0.1–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Phenoxyethanol~0.1–0.15%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Pentylene glycol, Polysorbate 20, Nymphaea alba flower extract, Sodium hyaluronate, Trehalose, Dipotassium glycyrrhizate, Caffeine, Phenylalanine, Proline, Glutamic acid, Aspartic acid, Arginine, Lysine, Serine, Alanine, Threonine, Histidine, Isoleucine, Tyrosine, Leucine, Valine, Glycine, Nymphaea alba root extract, Berberis vulgaris root extract, Polygala senega root extract, Hypnea musciformis extract, Sucrose, Sodium pca, Urea, Glycerin, Caprylyl glycol, Butylene glycol, Jojoba wax peg-120 esters, Citric acid, Dipropylene glycol, Hexylene glycol, Sodium hydroxide, Triacetin, Sodium palmitoyl proline, Ppg-5-ceteth-20, Chlorphenesin, Polyquaternium-51, Parfum, Sodium citrate, Disodium edta, Sodium benzoate, Potassium sorbate, Phenoxyethanol

Compare prices

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Amazon USPrice as of 10/30/2026 06:06 GMT
$39.10
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Bluemercury
$42.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Estée LauderPerfectly Clean Infusion Balancing Essence Lotion with Amino Acid and WaterlilyYOUR PRODUCTNu FormulaPro White Essence LotionEucerinUreaRepair Plus 10% Urea LotionThe OrdinaryNatural Moisturizing Factors + HA
Match—61%58%57%
Price$39.10—$15.01−$24.09$6.22−$32.88
Shared key ingredients—15 of 198 of 1913 of 19
Key difference—NiacinamideLactic AcidLinoleic Acid
Irritancy Medium Medium Low Medium
Drying alcohol————
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Product summary

"Estée Lauder - Perfectly Clean Infusion Balancing Essence Lotion with Amino Acid and Waterlily" is effective for: Moisturizing

This moisturizer could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Dipotassium Glycyrrhizate in this product (1.50% - 1.90%) can also further help improve the skin barrier. It might be able to calm down inflammation and reduce sensitivity. Dipotassium Glycyrrhizate is an active compound from the licorice root.

Price

The product retails for 42.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

  1. 1
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  6. 6
Estée Lauder Perfectly Clean Infusion Balancing Essence Lotion with Amino Acid and Waterlily
Estée LauderPerfectly Clean Infusion Balancing Essence Lotion with Amino Acid and Waterlily

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.