E45

E45 Itch Relief Gel

Name: E45 - Itch Relief Gel
Brand: E45

Efficacy100/100IrritancyLow

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Works for

1 of 1 advertised claim delivered

Moisturizing

3 ingredients credited for this claim

Strong support

What the product description says

“Formulated with Glycerin, to moisturise, soothe and heal skin, and Vitamin B5 to help attract and retain moisture.”

Source: Boots

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.7–7%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~1.2–1.9%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~3.7–5.5%

Can it cause trouble?

Irritancy

2 flagged ingredients

Low risk

We flag 2 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.

IngredientFunctionIrritationEst. amount

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~3.7–5.5%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.4–0.95%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

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Cheaper Alternatives

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Ingredients

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Water~40–60%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~4.7–7%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Pentylene glycol~3.7–5.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Methyl gluceth-10~2.2–3.2%

Formula

Irritation risk: Low

Works for

Cleansing

More about Methyl gluceth-10

Panthenol~1.2–1.9%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Acrylates/c10-30 alkyl acrylate crosspolymer~0.4–0.95%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Sodium gluconate~0.15–0.6%

Formula

Irritation risk: Low

Helps stabilize product formulations

More about Sodium gluconate

Sodium hydroxide~0.1–0.45%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Ingredient list view

Water, Glycerin, Pentylene glycol, Methyl gluceth-10, Panthenol, Acrylates/c10-30 alkyl acrylate crosspolymer, Sodium gluconate, Sodium hydroxide

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	E45Itch Relief GelYOUR PRODUCT	Beyou CosmeticsHyaluronic Acid Gel Moisturizer	ACUREUltra Hydrating Facial Gel Cream	CetaphilPRO Moisturising Night Cream
Match	—	67%	66%	64%
Price	$9.61	$45.00+$35.39	$9.99	$13.09+$3.48
Shared key ingredients	—	2 of 2	2 of 2	2 of 2
Key difference	—	Chondrus Crispus Extract	Caffeine	Niacinamide
Irritancy	Low	Low	Low	Low
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"E45 - Itch Relief Gel" is a well-rounded moisturizing product. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (panthenol and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (pentylene glycol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

An effective concentration of Panthenol (pro-vitamin B5) - about 1.20% - 1.90%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.