E45 Itch Relief Cream for Eczema & Itchy Skin
Works for
1 of 1 advertised claim delivered
MoisturizingUrea, Dimethicone + 5 moreStrong evidence
“Formulated with Urea, a moisturiser found naturally within the skin, E45 Itch Relief Cream is non-greasy, moisturising and will sooth your skin and leave it feeling calm and comfortable.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetyl palmitate.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: urea
Can it cause trouble?
Irritancy1 flagged ingredientLow risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
Be the first — your take helps the next person decide.
Ingredients
Filter by role to see what each ingredient is doing.
Urea5%
- Irritation risk
- Low
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
More about UreaLaureth-93%
Dimethicone~23–34%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconePhenyl dimethicone~3.8–5.7%
- Irritation risk
- Low
Cetyl palmitate~3.6–5.4%
- Irritation risk
- Low
An emollient that helps soften the skin and is used to improve product texture and stability
More about Cetyl palmitatePalmitic acid~2.5–3.7%
- Irritation risk
- Low
An emollient that is naturally present in skin and helps soften it
More about Palmitic acidOctyldodecanol~2.1–3.1%
- Irritation risk
- Low
An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation
More about OctyldodecanolCarbomer~1.6–2.4%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerGlycerin~1.5–2.2%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinBenzyl alcohol~0.5–1%
- Irritation risk
- High
A preservative. Can be used to mask unpleasant smell. Can be irritating
More about Benzyl alcoholWater~0.95–1.45%
Dimethicone~0.8–1.2%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconePhenyl dimethicone~0.45–1.05%
- Irritation risk
- Low
Paraffin~0.35–0.8%
- Irritation risk
- Low
Prevents water loss from the skin surface and thickens the product consistency
More about ParaffinCetyl palmitate~0.35–0.8%
- Irritation risk
- Low
An emollient that helps soften the skin and is used to improve product texture and stability
More about Cetyl palmitatePalmitic acid~0.3–0.7%
- Irritation risk
- Low
An emollient that is naturally present in skin and helps soften it
More about Palmitic acidOctyldodecanol~0.15–0.65%
- Irritation risk
- Low
An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation
More about OctyldodecanolGlycerin~0.1–0.45%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinCarbomer~0.05–0.25%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerBenzyl alcohol~0.05–0.1%
- Irritation risk
- High
A preservative. Can be used to mask unpleasant smell. Can be irritating
More about Benzyl alcoholWater~0.01–0.1%
Ingredient list view
Urea, Laureth-9, Dimethicone, Phenyl dimethicone, Cetyl palmitate, Unknown, Palmitic acid, Octyldodecanol, Unknown, Carbomer, Glycerin, Benzyl alcohol, Water, Dimethicone, Phenyl dimethicone, Unknown, Paraffin, Cetyl palmitate, Unknown, Palmitic acid, Octyldodecanol, Glycerin, Unknown, Carbomer, Benzyl alcohol, Water
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| E45Itch Relief Cream for Eczema & Itchy SkinYOUR PRODUCT | EucerinUrea Repair Face Cream 5% | ACOMiniderm Duo Cream | SimpleHydrating Light Moisturiser for Sensitive Skin | |
|---|---|---|---|---|
| Match | — | 63% | 62% | 62% |
| Price | — | $14.74 | — | $6.24 |
| Shared key ingredients | — | 3 of 3 | 3 of 3 | 3 of 3 |
| Key difference | — | Biosaccharide Gum-1 | Panthenol | Mineral Oil |
| Irritancy | Low | Low | Low | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Product summary
Judging from the ingredient list, "E45 - Itch Relief Cream for Eczema & Itchy Skin" works well for improving skin hydration This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Urea and glycerin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Dimethicone, cetyl palmitate, octyldodecanol, palmitic acid and paraffin in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 4 studies and safety reviews.
- 1Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
- 2
- 3Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
- 4
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