E45 Dermatitis Inflammation & Redness Cream

E45 Dermatitis Inflammation & Redness Cream

Efficacy100/100IrritancyLow
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Works for

1 of 1 advertised claim delivered

Moisturizing
11 ingredients credited for this claim
Strong support
What the product description says
“Dermatitis Inflammation & Redness Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 3

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~2.7–4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.05–0.25%
GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.3–0.75%
AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.15–0.65%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.4–2.1%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~1.7–2.5%
Ceramide 3Hero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~3.6–5.4%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~22–34%
Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~1.8–2.8%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.1–0.3%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.15–0.65%

Can it cause trouble?

Irritancy
4 flagged ingredients
Low risk
We flag 4 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Cardiospermum halicacabum flower/leaf/vine extractA plant extract that might have some anti-inflammatory and anti-oxidant properties but evidence is missingHigh~0.4–0.9%est.
Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~1.8–2.8%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~1.7–2.5%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.15–0.65%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.4–2.1%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Ectoin~22–34%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Water~12–18%
Formula
Irritation risk
Low

Plain old water

More about Water
Hydrogenated lecithin~3.6–5.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Ceramide 3~3.6–5.4%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide 3
Squalane~2.7–4%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Olea europaea fruit oil~1.8–2.8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil
Caprylic/capric triglyceride~1.7–2.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Butyrospermum parkii butter~1.4–2.1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Oryza sativa bran cera~1.1–1.6%
Formula
Carbomer~0.9–1.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Xanthan gum~0.5–1.2%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Sodium carbomer~0.5–1.2%
Formula
Irritation risk
Low

Helps improve the texture

More about Sodium carbomer
Cardiospermum halicacabum flower/leaf/vine extract~0.4–0.9%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

A plant extract that might have some anti-inflammatory and anti-oxidant properties but evidence is missing

More about Cardiospermum halicacabum flower/leaf/vine extract
Glycine~0.3–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine
Alanine~0.15–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Pentylene glycol~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Butylene glycol~0.1–0.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Hydroxyethylcellulose~0.1–0.35%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Glycerin~0.05–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydroxyphenyl propamidobenzoic acid~0.05–0.2%
Formula
Irritation risk
Low
Works for
Anti-inflammatory

Might help to reduce inflammation in skin, but solid research is lacking

More about Hydroxyphenyl propamidobenzoic acid
Ingredient list view

Ectoin, Water, Hydrogenated lecithin, Ceramide 3, Squalane, Olea europaea fruit oil, Caprylic/capric triglyceride, Butyrospermum parkii butter, Oryza sativa bran cera, Carbomer, Xanthan gum, Sodium carbomer, Cardiospermum halicacabum flower/leaf/vine extract, Glycine, Alanine, Pentylene glycol, Butylene glycol, Hydroxyethylcellulose, Glycerin, Hydroxyphenyl propamidobenzoic acid

Compare prices

Retailers ranked by price — lowest first.

Supderdrug
≈ $23.78
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Amazon UKPrice as of 10/3/2026 15:31 GMT
≈ $24.80
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Affiliate links · prices updated regularly · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
E45Dermatitis Inflammation & Redness CreamYOUR PRODUCTBootsDermacare Eczema Treatment CreamDermavidualsDMS base cream high classicGenus SkincarePhysio~Logic Fortifying Moisturiser
Match—75%57%55%
Price$23.78$13.21−$10.57—$39.66+$15.88
Shared key ingredients—8 of 85 of 85 of 8
Key difference———Niacinamide
Irritancy Low Low Low Low
Drying alcohol————
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Product summary

Based on the ingredient list, "E45 - Dermatitis Inflammation & Redness Cream" can work well for skin moisturization. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (alanine, glycerin, glycine and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide 3, butyrospermum parkii butter, caprylic/capric triglyceride, squalane and olea europaea fruit oil in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • As a plus, this moisturizer also contains ceramides (ceramide 3 3.60% - 5.40%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.

Irritation risk

This moisturizer contains actives that can be irritating. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 22.99$ in the United States and from 15.88£ up to 17.99£ in the United Kingdom.

For a detailed price comparison: click here.

E45 Dermatitis Inflammation & Redness Cream
E45Dermatitis Inflammation & Redness Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.