DR.PHAMOR McCELL SKIN SCIENCE 365 Syn-Ake Gold Hand Cream
Works for
MoisturizingDipeptide diaminobutyroyl benzylamide diacetate, Glycerin + 7 moreWorks well
“Enriched with a patented ingredient called Syn-ake, a kind of peptide similar in structure to snake venom, and various types of natural plant extracts, this hand cream nourishes and moisturizes skin.”
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: dipeptide diaminobutyroyl benzylamide diacetate
Anti-agingSide benefit · Adenosine, Dipeptide diaminobutyroyl benzylamide diacetate + 1 moreWorks well
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: dipeptide diaminobutyroyl benzylamide diacetate.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Anti-oxidationSide benefit · Ilex paraguariensis leaf extract, Adenosine + 2 moreMay help
This product contains antioxidants (ilex paraguariensis leaf extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Can it cause trouble?
Irritancy5 strong irritants: Parfum, Ilex paraguariensis leaf extract + 3 more — patch-test recommendedHigh risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
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Ingredients
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Water~40–60%
Glycerin~3.8–5.7%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinCetyl alcohol~3.2–4.7%
- Irritation risk
- Low
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
More about Cetyl alcoholPolysorbate 60~2.4–3.6%
Glyceryl stearate~2–3%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearateSorbitan stearate~1.6–2.5%
Phenoxyethanol~0.5–1%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolPeg-100 stearate~1.3–1.9%
- Irritation risk
- Low
Helps oil and water mix togehter and creates a nice product texture
More about Peg-100 stearateStearic acid~1.1–1.6%
- Irritation risk
- Low
Helps oil and water mix together and works as an emollient
More about Stearic acidTriethanolamine~0.6–1.4%
- Irritation risk
- Medium
Used to adjust pH of the product and can help improve the product's smell
More about TriethanolamineAllantoin~0.4–0.9%
- Irritation risk
- Low
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
More about AllantoinDisodium edta~0.4–0.9%
Adenosine~0.35–0.8%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineParfum~0.3–0.75%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumDipeptide diaminobutyroyl benzylamide diacetate~0.2–0.75%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Dipeptide diaminobutyroyl benzylamide diacetateAloe barbadensis leaf extract~0.3–0.7%
- Irritation risk
- Medium
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
More about Aloe barbadensis leaf extractVaccinium angustifolium fruit extract~0.1–0.5%
- Irritation risk
- Medium
A plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lacking
More about Vaccinium angustifolium fruit extractIlex paraguariensis leaf extract~0.1–0.45%
- Irritation risk
- High
A plant extract that can help neutralize free radicals in skin. Can contain fragrand compounds like linalool that can be irritating
More about Ilex paraguariensis leaf extractHamamelis virginiana leaf extract~0.1–0.4%
- Irritation risk
- High
A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating
More about Hamamelis virginiana leaf extractArnica montana flower extract~0.05–0.3%
- Irritation risk
- High
A plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skin
More about Arnica montana flower extractGentiana lutea root extract~0.05–0.3%
- Irritation risk
- Medium
A plant extract that can help strengthen the skin barrier function and improve skin moisture levels
More about Gentiana lutea root extractAchillea millefolium extract~0.1–0.35%
- Irritation risk
- High
Plant extract that can help neutralize free radicals in skin. Can be used as a fragrance. Can be irritating
More about Achillea millefolium extractArtemisia princeps extract~0.05–0.15%
- Irritation risk
- High
A plant extract that might have some anti-inflammatory and anti-oxidant properties
More about Artemisia princeps extractGold0.0005%
Ingredient list view
Water, Glycerin, Cetyl alcohol, Polysorbate 60, Glyceryl stearate, Sorbitan stearate, Phenoxyethanol, Peg-100 stearate, Stearic acid, Triethanolamine, Allantoin, Disodium edta, Adenosine, Parfum, Dipeptide diaminobutyroyl benzylamide diacetate, Aloe barbadensis leaf extract, Vaccinium angustifolium fruit extract, Ilex paraguariensis leaf extract, Hamamelis virginiana leaf extract, Arnica montana flower extract, Gentiana lutea root extract, Achillea millefolium extract, Artemisia princeps extract, Gold
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| DR.PHAMORMcCELL SKIN SCIENCE 365 Syn-Ake Gold Hand CreamYOUR PRODUCT | Secret KeySYN-AKE Anti Wrinkle & Whitening Eye Cream | MEDI-PEELPremium Naite Thread Neck Cream | NEOGEN X SUR.MEDICSurmedic 24K Gold Caviar Repair Vital Cream | |
|---|---|---|---|---|
| Match | — | 53% | 53% | 53% |
| Price | — | $13.04 | $21.71 | $60.00 |
| Shared key ingredients | — | 3 of 5 | 3 of 5 | 4 of 5 |
| Key difference | — | Niacinamide | Ceramide 3 | Hexapeptide-11 |
| Irritancy | High | Medium | High | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: DPC Eye Tox Radiance Eye CreamMizon S-Venom Wrinkle Tox Cream
Product summary
Judging from the ingredient list, "DR. PHAMOR - McCELL SKIN SCIENCE 365 Syn-Ake Gold Hand Cream" works well for improving skin hydration To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. DR. PHAMOR - McCELL SKIN SCIENCE 365 Syn-Ake Gold Hand Cream ticks this box. Humectants in this product (glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Cetyl alcohol, glyceryl stearate and stearic acid in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- We like that this moisturizer contains peptides (dipeptide diaminobutyroyl benzylamide diacetate 0.20% - 0.80%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Adenosine 0.35% - 0.80%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Irritation risk
This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 11.50$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 13 studies and safety reviews.
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