Works for:
based on ingredients and %- Moisturizing
- Anti-aging
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 1
Key actives
Product Summary
Based on the ingredient list, "Dr. Different - 113 Moisturizer" can work well for skin moisturization. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Alanine, arginine, glutamic acid, glycerin and glycine in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, phytosphingosine, cholesterol, glycosphingolipids and hydroxypropyl bispalmitamide mea) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- Another benefit is that this moisturizer contain ceramides (phytosphingosine 0.15% - 0.30% and ceramide np 0.25% - 0.45%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
- Adenosine 0.25% - 0.45%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails from 27.18$ up to 37.00$ in the United States.
For a detailed price comparison: click here.
Works for
Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: serine.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Moisturizing
What does the product description say?
113 Moisturizer
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
alanine, arginine.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylic/capric triglyceride.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, phytosphingosine
A type of lipids naturally present in skin. They can be converted to ceramides in skin
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
Naturally present in skin and helps to attract water to its upper layer
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An emollient that is naturally found in skin
An amino-acid that helps attract water to the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Used to stabilize the product formulations and works as an emollient
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
Helps preserve products and creates a nice product texture
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
An emollient that is naturally present in skin and helps soften it
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps to stabilize the product formulation while softening the upper layer of the skin. Can be irritating
An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores
Helps oil and water mix together and works as an emollient
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Dr.Different 113 Moisturizer | Current | $27.18 | |
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Key Actives
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
An emollient that is naturally found in skin
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Naturally present in skin and helps to attract water to its upper layer
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
An amino-acid that helps attract water to the upper layer of the skin
A type of lipids naturally present in skin. They can be converted to ceramides in skin
Potential irritants
Used to help oil and water mix together. Can be irritating
Helps to stabilize the product formulation while softening the upper layer of the skin. Can be irritating
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Used to create a thicker product consistency
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
Helps preserve products and creates a nice product texture
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
A plant extract that might have some anti-oxidant properties, but evidence is lacking
Comedogenic ingredients
Used to stabilize the product formulations and works as an emollient
All ingredients
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Used to create a thicker product consistency
Used to stabilize the product formulations and works as an emollient
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Used to help oil and water mix together. Can be irritating
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
Helps to stabilize the product formulation while softening the upper layer of the skin. Can be irritating
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Used to creat a nice product texture and support penetration of other ingredients
Helps preserve products and creates a nice product texture
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
An emollient that is naturally present in skin and helps soften it
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores
Naturally present in skin and helps to attract water to its upper layer
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
A plant extract that might have some anti-oxidant properties, but evidence is lacking
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An amino-acid that helps attract water to the upper layer of the skin
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
A type of lipids naturally present in skin. They can be converted to ceramides in skin
Ingredient list view
Water, Caprylic/capric triglyceride, Butylene glycol, Glycerin, Pentaerythrityl tetraisostearate, 1,2-hexanediol, Glyceryl stearate se, Cetyl alcohol, Stearyl alcohol, Cetearyl olivate, Cholesterol, Sorbitan sesquioleate, Olea europaea fruit oil, Sorbitan olivate, Hydroxypropyl bispalmitamide mea, Stearic acid, Carbomer, Ethylhexylglycerin, Myristyl alcohol, Arginine, Isomerized linoleic acid, Lauryl alcohol, Decylene glycol, Caprylyl glycol, Xanthan gum, Adenosine, Oleic acid, Palmitic acid, Tocopherol, Mevalonolactone, Hydrogenated phosphatidylcholine, Linoleic acid, Sodium pca, Serine, Glycine, Tremella fuciformis polysaccharide, Rosa canina fruit extract, Ceramide np, Alanine, Glutamic acid, Cholesteryl macadamiate, Sucrose stearate, Phytosphingosine, Glycosphingolipids
- Glycerol and the skin: holistic approach to its origin and functions
- Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Sorbitan sesquioleate, a common emulsifier in topical corticosteroids, is an important contact allergen
- Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oil
- Cosmetic allergy from myristyl alcohol
- Contact Sensitization to Emulsifying Agents: An Underrated Issue?
- Patch testing with myristyl alcohol
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
- https://www.sciencedirect.com/science/article/pii/0168365995000887
- Vitamin E in dermatology
- Vitamin E and Skin Health
- The Permeability Barrier in Essential Fatty Acid Deficiency: Evidence for a Direct Role for Linoleic Acid in Barrier Function
- Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones.
- Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
- Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiency
- Functional glycine receptor in cultured human keratinocytes
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Combination of amino acids reduces pigmentation in B16F0 melanoma cells