Dr. Brandt Cool Biotic Cream

Dr. Brandt Cool Biotic Cream

Efficacy100/100IrritancyMedium
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Works for

1 of 1 advertised claim delivered

Moisturizing
15 ingredients credited for this claim
Strong support
What the product description says
“It’s beneficial in helping redness appear less prominent while hydrating drier areas for a more natural finish.”
Source: Mankind

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: fructose, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, cannabis sativa seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.6–0.9%
FructoseKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.4–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.25–0.5%
InulinKey activeEffect: HighHelps attract water to the upper layer of the skin. Is claimed to support the growth of "good" bacteria in skin (as a "prebiotic"), but the research is lacking~0.25–0.45%
Lactococcus ferment lysateKey activeEffect: HighConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin~1.4–1.7%
SucroseKey active· HumectantEffect: HighCan help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion~0.35–0.65%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~6.7–8.2%
Cannabis sativa seed oilKey active· EmollientEffect: HighA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer~1.7–2%
Polyglyceryl-6 stearateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~2–2.4%
GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.3–0.6%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~2.6–3.1%
Avena sativa kernel flourEffect: LowA type of colloidal oatmeal. Can contain potent antioxidants and anti-inflammatory compounds. Is effective in supporting skin barrier~1.4–1.7%
Ophiopogon japonicus root extractEffect: LowPlant extract that might help neutralize free radicals and support skin barrier function, but research on its effectiveness in skin is lacking~0.8–1.2%
Lactic acidUnder-dosedEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.5%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.55%
Anti-oxidation
Not advertised by the brand · 5 ingredients credited for this claim
Strong support

This product contains antioxidants (vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Vitis vinifera seed extractKey activeEffect: HighA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.25–0.5%
Lactococcus ferment lysateEffect: LowConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin~1.4–1.7%
Ocimum sanctum leaf extractEffect: LowA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals~0.25–0.5%
Ophiopogon japonicus root extractEffect: LowPlant extract that might help neutralize free radicals and support skin barrier function, but research on its effectiveness in skin is lacking~0.8–1.2%
Camellia sinensis leaf extractUnder-dosedEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.55%
Anti-aging
Not advertised by the brand · 4 ingredients credited for this claim
Moderate support

This product contains vitis vinifera seed extract. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Vitis vinifera seed extractKey activeEffect: MediumA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.25–0.5%
Lactococcus ferment lysateEffect: LowConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin~1.4–1.7%
Lactic acidUnder-dosedEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.5%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.55%

Can it cause trouble?

Irritancy
1 strong irritant: Ocimum sanctum leaf extract
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.25–0.5%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.1–0.2%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~6.7–8.2%est.
Cannabis sativa seed oilA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layerMedium~1.7–2%est.
Ophiopogon japonicus root extractPlant extract that might help neutralize free radicals and support skin barrier function, but research on its effectiveness in skin is lackingMedium~0.8–1.2%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.5–0.7%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.25–0.5%est.
Polyglyceryl-6 behenateHelps oil and water mix togetherMedium~0.25–0.45%est.
EthylhexylglycerinA preservativeMedium~0.2–0.4%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.15–0.25%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.1%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Enteromorpha compressa extract—3/5~0.5–0.75%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~6.7–8.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Hydroxystearic acid~4.4–5.4%
Formula
Irritation risk
Low
Works for
Cleansing
More about Hydroxystearic acid
Cetyl alcohol~2.6–3.1%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Stearyl alcohol~2.4–2.9%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Polyglyceryl-6 stearate~2–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Polyglyceryl-6 stearate
Cannabis sativa seed oil~1.7–2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer

More about Cannabis sativa seed oil
Lactococcus ferment lysate~1.4–1.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-oxidationAnti-aging

Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin

More about Lactococcus ferment lysate
Avena sativa kernel flour~1.4–1.7%
Formula
Irritation risk
Low
Works for
Moisturizing

A type of colloidal oatmeal. Can contain potent antioxidants and anti-inflammatory compounds. Is effective in supporting skin barrier

More about Avena sativa kernel flour
Ophiopogon japonicus root extract~0.8–1.2%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Plant extract that might help neutralize free radicals and support skin barrier function, but research on its effectiveness in skin is lacking

More about Ophiopogon japonicus root extract
Yogurt~0.65–1%
Formula
Irritation risk
Low
More about Yogurt
Ceramide np~0.6–0.9%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Enteromorpha compressa extract~0.5–0.75%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
More about Enteromorpha compressa extract
Polysorbate 60~0.5–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Sorbitan isostearate~0.45–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Sucrose~0.35–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Can help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion

More about Sucrose
Fructose~0.4–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Fructose
Glucose~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose
Camellia sinensis leaf extract~0.3–0.55%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingMoisturizingEvens skin toneAnti-blemish

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Ocimum sanctum leaf extract~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract
Silybum marianum fruit extract~0.25–0.5%
Formula
Lactic acid~0.25–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingExfoliationEvens skin toneAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Vitis vinifera seed extract~0.25–0.5%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingAntibacterial

A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation

More about Vitis vinifera seed extract
Inulin~0.25–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-blemish

Helps attract water to the upper layer of the skin. Is claimed to support the growth of "good" bacteria in skin (as a "prebiotic"), but the research is lacking

More about Inulin
Maltodextrin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Glycerin~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Polyglyceryl-6 behenate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Polyglyceryl-6 behenate
Ethylhexylglycerin~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Propanediol~0.25–0.4%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Benzyl alcohol~0.1–0.2%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Methyl lactate~0.15–0.25%
Formula
Irritation risk
Low
More about Methyl lactate
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Sodium chloride~0.15–0.25%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Citric acid~0.05–0.1%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ingredient list view

Water, Caprylic/capric triglyceride, Hydroxystearic acid, Cetyl alcohol, Stearyl alcohol, Polyglyceryl-6 stearate, Cannabis sativa seed oil, Lactococcus ferment lysate, Avena sativa kernel flour, Ophiopogon japonicus root extract, Yogurt, Ceramide np, Enteromorpha compressa extract, Polysorbate 60, Sorbitan isostearate, Sucrose, Fructose, Glucose, Camellia sinensis leaf extract, Ocimum sanctum leaf extract, Silybum marianum fruit extract, Lactic acid, Vitis vinifera seed extract, Inulin, Maltodextrin, Glycerin, Polyglyceryl-6 behenate, Ethylhexylglycerin, Propanediol, Benzyl alcohol, Methyl lactate, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Sodium chloride, Sodium benzoate, Citric acid

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Product summary

"Dr. Brandt - Cool Biotic Cream" is a well-rounded moisturizing product. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Fructose, glycerin, sucrose and glucose in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide np, cannabis sativa seed oil, caprylic/capric triglyceride, cetyl alcohol and polyglyceryl-6 stearate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • Another benefit is that this moisturizer contain ceramides (ceramide np 0.60% - 0.90%). Ceramides are an important part of our natural skin barrier. The ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 55.00$ in the United States, for 70.08CA$ in Canada and from 42.90£ up to 45.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 14 studies and safety reviews.

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