Dermacol Bio Retinol

Dermacol Bio Retinol

Efficacy0/100IrritancyHigh

Works for

Anti-aging
Lactic acid ~0.2–0.4%
Under-dosed

Effective ingredients missing or their concentration is too low.

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.6–0.85%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.2–0.4%
Evens skin tone
Lactic acid ~0.2–0.4%
Under-dosed

Effective ingredients missing or their concentration is too low

Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.2–0.4%
Exfoliation
Lactic acid ~0.2–0.4%
Under-dosed

This product does not contain effective exfoliating ingredients. It might be able to deliver physical exfoliation, that is scrub off some of the dead cells on the surface of the skin. We do not recommend physical exfoliation, because it is not uniform (some bits of skin can get exfoliated too much while others not at all). It can also traumatize the skin and aggrevate acne and other skin conditions.

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.4–0.6%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.2–0.4%
Moisturizing
Side benefit · Glycerin, Glycine soja oil + 11 more
Works

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, glycine soja oil.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.7–5.7%
Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~4.1–5%
Chlorella vulgaris extractKey activeEffect: MediumA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~2.3–2.8%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.75–1.15%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.5–0.75%
Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~0.45–0.7%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.8–3.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.6–0.85%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.55%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.4–0.6%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.3–0.55%
Avena sativa kernel oilUnder-dosedAn effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties~0.3–0.55%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.2–0.4%

Can it cause trouble?

Irritancy
19 flagged ingredients — patch-test recommended
High risk
We flagged 19 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.15–0.3%est.
CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.15–0.3%est.
Cinnamyl alcohol—High~0.15–0.25%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.15–0.25%est.
LinaloolA fragrance. Can be irritatingHigh~0.15–0.25%est.
CitronellolA fragrance. Can be irritatingHigh~0.1–0.2%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.15%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~4.1–5%est.
Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory propertiesMedium~2.3–2.8%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~1.5–1.9%est.
Acacia senegal gumHelps mask the small of other ingredients and improve the product textureMedium~1–1.2%est.
EthylhexylglycerinA preservativeMedium~0.5–0.7%est.
Ceteareth-12Helps water and oil mix togetherMedium~0.4–0.6%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.55%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.5%est.
Diethylhexyl syringylidenemalonateUsed to stabilize the product formulationMedium~0.25–0.5%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.3–0.55%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.2–0.4%est.
Ci 17200A red colorantMedium~0.05–0.15%est.
Comedogenic
4 ingredients rated 2 or more on the 0–5 pore-clogging scale
4 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties3/5~2.3–2.8%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~4.1–5%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~1.5–1.9%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.5–0.75%est.

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Ingredients

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Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.7–5.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Glycine soja oil~4.1–5%
Key activeComedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil
Glyceryl stearate~2.8–3.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Chlorella vulgaris extract~2.3–2.8%
Key activeComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-inflammatory

A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties

More about Chlorella vulgaris extract
Dipentaerythrityl pentaisononanoate~1.9–2.4%
Formula
Phenoxyethanol~0.5–1%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ceteareth-20~1.5–1.9%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
Propanediol~1.2–1.5%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Acacia senegal gum~1–1.2%
Irritant · medium
Irritation risk
Medium

Helps mask the small of other ingredients and improve the product texture

More about Acacia senegal gum
Squalane~0.75–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Tocopherol~0.6–0.85%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Xanthan gum~0.5–0.8%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Ethylhexylglycerin~0.5–0.7%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Allantoin~0.4–0.6%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Cetearyl alcohol~0.5–0.75%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Cetyl palmitate~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate
Ceteareth-12~0.4–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Ceteareth-12
Avena sativa kernel oil~0.3–0.55%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

An effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties

More about Avena sativa kernel oil
Tocopheryl acetate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Disodium edta~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Diethylhexyl syringylidenemalonate~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Used to stabilize the product formulation

More about Diethylhexyl syringylidenemalonate
Lecithin~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Sodium hydroxide~0.25–0.45%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Caprylic/capric triglyceride~0.3–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Lactic acid~0.2–0.4%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Sodium chloride~0.25–0.45%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Saccharomyces lysate extract filtrate~0.2–0.4%
Formula
Alpha-isomethyl ionone~0.15–0.3%
Irritant · high
Irritation risk
High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone
Coumarin~0.15–0.3%
Irritant · high
Irritation risk
High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin
Cinnamyl alcohol~0.15–0.25%
Irritant · high
Limonene~0.15–0.25%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Linalool~0.15–0.25%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Citronellol~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Parfum~0.05–0.15%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ci 17200~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A red colorant

More about Ci 17200
Ingredient list view

Water, Glycerin, Glycine soja oil, Glyceryl stearate, Chlorella vulgaris extract, Dipentaerythrityl pentaisononanoate, Phenoxyethanol, Ceteareth-20, Propanediol, Acacia senegal gum, Squalane, Tocopherol, Xanthan gum, Ethylhexylglycerin, Allantoin, Cetearyl alcohol, Cetyl palmitate, Ceteareth-12, Avena sativa kernel oil, Tocopheryl acetate, Disodium edta, Diethylhexyl syringylidenemalonate, Lecithin, Sodium hydroxide, Caprylic/capric triglyceride, Lactic acid, Sodium chloride, Saccharomyces lysate extract filtrate, Alpha-isomethyl ionone, Coumarin, Cinnamyl alcohol, Limonene, Linalool, Citronellol, Parfum, Ci 17200

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
DermacolBio RetinolYOUR PRODUCTIOPERetinol Expert 0.3%TopicalsFaded Brightening & Clearing Serum MiniLise WatierAge Control Supreme Sublime Advanced Night Cream
Match—42%41%40%
Price—$79.00$33.63$92.89
Shared key ingredients—5 of 75 of 75 of 7
Key difference—Acetyl Tetrapeptide-11Azelaic AcidButyrospermum Parkii Butter
Irritancy High Medium Medium Medium
Drying alcohol————
View product Shop Shop Shop

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Product summary

"Dermacol - Bio Retinol" could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Humectants (glycerin 4.70% - 5.70%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 6 studies and safety reviews.

  1. 1
  2. 2
    Vitamin E in dermatologyncbi.nlm.nih.gov
  3. 3
    Vitamin E and Skin Healthlpi.oregonstate.edu
  4. 4
  5. 5
  6. 6
Dermacol Bio Retinol
DermacolBio Retinol

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