Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Exfoliation
- Anti-oxidation
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"Depology - Peptide Complex 10% Argireline™ peptide Serum" is effective for: Moisturizing and Exfoliation
This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- Ceramides (ceramide np 0.35% - 0.85%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- Peptides (hexapeptide-9 0.05% - 0.30%, palmitoyl tripeptide-5 0.10% - 0.35%, ascorbic acid polypeptide 0.15% - 0.65% and acetyl hexapeptide-8 0.35% - 0.85%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- An effective concentration of Panthenol (pro-vitamin B5) - about 2.70% - 4.10%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
- Humectants (hexapeptide-9 0.05% - 0.30%, acetyl hexapeptide-8 0.35% - 0.85%, sodium hyaluronate 0.80% - 1.25%, glycerin 1.10% - 1.60%, hydroxyethyl urea 2.10% - 3.10% and panthenol 2.70% - 4.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Works for
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: hydroxyethyl urea.
A derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients
Moisturizing
What does the product description say?
This serum not only combats wrinkles, but also delivers preventive benefits whilst replenishing moisture back into the skin.
Source: N/A
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hydroxyethyl urea.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: ceramide np, caprylyl glycol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ascorbic acid polypeptide, ceramide np, hexapeptide-9, palmitoyl tripeptide-5, panthenol
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps attract water to the upper layer of the skin and can help improve skin barrier function
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps preserve products and creates a nice product texture
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Anti-aging
What does the product description say?
Enhanced Peptide Serum Solution Formulated to Combat Fine Lines and Wrinkle Formation.
Source: N/A
This product contains acetyl hexapeptide-8, ascorbic acid polypeptide, hexapeptide-9, palmitoyl tripeptide-5. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Anti-oxidation
This product contains antioxidants (ascorbic acid polypeptide, ficus carica fruit extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
A type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Anti-aging |
Total Promises Fulfilled score: 87/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 Depology Peptide Complex 10% Argireline™ peptide Serum | Current | $49.00 | |
 Mizon Collagen 100 | 50% | $11.96 |
Key Actives
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect
Potential irritants
An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin
An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties
Helps preserve products and creates a nice product texture
A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
Helps preserve products and creates a nice product texture
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.
An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Increases thickness of a product. Texture enhancer for oil-in-water emulsions
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Used to stabilize the product formulation and can help absorb oil
An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties
Ingredient list view
Water, Isopentyldiol, 1,2-hexanediol, Panthenol, Hydroxyethyl urea, Butylene glycol, Propanediol, Caprylyl glycol, Glycerin, Sodium hyaluronate, Ficus carica fruit extract, Centella asiatica extract, Acetyl hexapeptide-8, Ceramide np, Hydrogenated lecithin, Anthemis nobilis flower oil, Tocopherol, Houttuynia cordata extract, Tocopheryl acetate, Ascorbic acid polypeptide, Ammonium acryloyldimethyltaurate/vp copolymer, Tromethamine, Carbomer, Octyldodeceth-16, Ethylhexylglycerin, Acrylates/c10-30 alkyl acrylate crosspolymer, Disodium edta, Palmitoyl tripeptide-5, Pinus strobus bark extract, Hexapeptide-9, Maltodextrin, Lavandula angustifolia oil, Linalool
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Safety Assessment of Hydroxyethyl Urea As Used in Cosmetics
- Glycerol and the skin: holistic approach to its origin and functions
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model
- Centella asiatica in cosmetology
- Triterpene Composition and Bioactivities of Centella asiatica
- Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts
- Assessment report on Centella asiatica (L.) Urban, herba
- Contact dermatitis due to Madecassol
- The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Safety Assessment of Anthemis nobilis– Derived Ingredients as Used in Cosmetics
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Safety Assessment of Tromethamine as Used in Cosmetics