Depology Peptide Complex 10% Argireline peptide Serum
Works for
MoisturizingPanthenol, Acetyl hexapeptide-8 + 11 moreWorks well
“A powerful serum formulated with Argireline™ peptide, clinically proven to improve the appearance of wrinkles and lines while supporting hydration for a smoother, replenished complexion.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hydroxyethyl urea.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: ceramide np, caprylyl glycol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ascorbic acid polypeptide, ceramide np, hexapeptide-9, palmitoyl tripeptide-5, panthenol
Anti-agingAcetyl hexapeptide-8, Centella asiatica extract + 4 moreMay help
“A powerful serum formulated with Argireline™ peptide, clinically proven to improve the appearance of wrinkles and lines while supporting hydration for a smoother, replenished complexion.”
This product contains acetyl hexapeptide-8, ascorbic acid polypeptide, centella asiatica extract, hexapeptide-9, palmitoyl tripeptide-5. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
ExfoliationSide benefit · Hydroxyethyl ureaWorks well
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: hydroxyethyl urea.
Anti-oxidationSide benefit · Ficus carica fruit extract, Centella asiatica extract + 4 moreMay help
This product contains antioxidants (ascorbic acid polypeptide, centella asiatica extract, ficus carica fruit extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Can it cause trouble?
Irritancy2 strong irritants: Lavandula angustifolia oil, LinaloolMedium risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
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Ingredients
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Water~40–60%
Isopentyldiol~5.7–8.6%
1,2-hexanediol~1.8–2.7%
Panthenol~2.7–4.1%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and can help improve skin barrier function
More about PanthenolHydroxyethyl urea~2.1–3.1%
- Irritation risk
- Low
A derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients
More about Hydroxyethyl ureaButylene glycol~1.7–2.6%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolPropanediol~1.5–2.2%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolCaprylyl glycol~1.3–1.9%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolGlycerin~1.1–1.6%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinSodium hyaluronate~0.8–1.25%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateFicus carica fruit extract~0.5–1.15%
- Irritation risk
- Medium
A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect
More about Ficus carica fruit extractCentella asiatica extract~0.35–0.85%
- Irritation risk
- Medium
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
More about Centella asiatica extractAcetyl hexapeptide-8~0.35–0.85%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Ceramide np~0.35–0.85%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide npHydrogenated lecithin~0.35–0.75%
- Irritation risk
- Low
Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.
More about Hydrogenated lecithinAnthemis nobilis flower oil~0.2–0.75%
- Irritation risk
- High
An essential oil that is used as a fragrance and can be irritating. It might have some anti-oxidant effect in skin
More about Anthemis nobilis flower oilTocopherol~0.3–0.7%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolHouttuynia cordata extract~0.2–0.75%
- Irritation risk
- Low
Tocopheryl acetate~0.2–0.7%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetateAscorbic acid polypeptide~0.15–0.65%
- Irritation risk
- Low
A type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Ascorbic acid polypeptideAmmonium acryloyldimethyltaurate/vp copolymer~0.15–0.6%
- Irritation risk
- Low
Increases thickness of a product. Texture enhancer for oil-in-water emulsions
More about Ammonium acryloyldimethyltaurate/vp copolymerTromethamine~0.15–0.55%
Carbomer~0.15–0.5%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerOctyldodeceth-16~0.15–0.55%
Ethylhexylglycerin~0.1–0.5%
Acrylates/c10-30 alkyl acrylate crosspolymer~0.1–0.5%
- Irritation risk
- Medium
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
More about Acrylates/c10-30 alkyl acrylate crosspolymerDisodium edta~0.1–0.4%
Palmitoyl tripeptide-5~0.1–0.35%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-5Pinus strobus bark extract~0.1–0.35%
- Irritation risk
- Low
Hexapeptide-9~0.05–0.3%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Hexapeptide-9Maltodextrin~0.05–0.25%
- Irritation risk
- Low
Used to stabilize the product formulation and can help absorb oil
More about MaltodextrinLavandula angustifolia oil~0.05–0.15%
- Irritation risk
- High
An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties
More about Lavandula angustifolia oilLinalool~0.05–0.1%
Ingredient list view
Water, Isopentyldiol, 1,2-hexanediol, Panthenol, Hydroxyethyl urea, Butylene glycol, Propanediol, Caprylyl glycol, Glycerin, Sodium hyaluronate, Ficus carica fruit extract, Centella asiatica extract, Acetyl hexapeptide-8, Ceramide np, Hydrogenated lecithin, Anthemis nobilis flower oil, Tocopherol, Houttuynia cordata extract, Tocopheryl acetate, Ascorbic acid polypeptide, Ammonium acryloyldimethyltaurate/vp copolymer, Tromethamine, Carbomer, Octyldodeceth-16, Ethylhexylglycerin, Acrylates/c10-30 alkyl acrylate crosspolymer, Disodium edta, Palmitoyl tripeptide-5, Pinus strobus bark extract, Hexapeptide-9, Maltodextrin, Lavandula angustifolia oil, Linalool
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| DepologyPeptide Complex 10% Argireline peptide SerumYOUR PRODUCT | MizonCollagen 100 | MEDIHEALBaobab Soothing Moisture Serum | AbibCopper Peptide Serum Bouncing Drop – GHK-Cu, Argireline & Matrixyl Anti-Aging Face Serum | Wrinkle Care, Plumping & Firming Korean Skincare | |
|---|---|---|---|---|
| Match | — | 51% | 49% | 49% |
| Price | $49.00 | $13.40−$35.60 | — | $35.00−$14.00 |
| Shared key ingredients | — | 6 of 12 | 6 of 12 | 7 of 12 |
| Key difference | — | Copper Tripeptide-1 | Copper Tripeptide-1 | Tripeptide-1 |
| Irritancy | Medium | Low | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Bliv:U Collagen Bouncing Serum PadArencia Deep Water Surge Sun Serum
Product summary
"Depology - Peptide Complex 10% Argireline™ peptide Serum" is effective for: Moisturizing and Exfoliation
This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- Ceramides (ceramide np 0.35% - 0.85%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- Peptides (hexapeptide-9 0.05% - 0.30%, palmitoyl tripeptide-5 0.10% - 0.35%, ascorbic acid polypeptide 0.15% - 0.65% and acetyl hexapeptide-8 0.35% - 0.85%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- An effective concentration of Panthenol (pro-vitamin B5) - about 2.70% - 4.10%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
- Humectants (hexapeptide-9 0.05% - 0.30%, acetyl hexapeptide-8 0.35% - 0.85%, sodium hyaluronate 0.80% - 1.25%, glycerin 1.10% - 1.60%, hydroxyethyl urea 2.10% - 3.10% and panthenol 2.70% - 4.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 20 studies and safety reviews.
- 1
- 2Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
- 3
- 4
- 5
- 6Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
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