DECLEOR Antidote Serum

DECLEOR Antidote Serum

Efficacy75/100IrritancyHigh

Works for

Anti-aging
Adenosine, Tocopherol
Works well
What the product description says
“Wake up tired skin with Parisian aromatherapy specialists DECLÉOR ’s Antidote Serum ; a multitasking, skin-refining serum that protects, revitalises, moisturises and firms slackening skin in need of some TLC, with a 97% natural-origin formulation.”
Source: Mankind

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.7%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.2%
Moisturizing
Glycerin, Hydroxypropyl tetrahydropyrantriol + 11 more
Works
What the product description says
“Wake up tired skin with Parisian aromatherapy specialists DECLÉOR ’s Antidote Serum ; a multitasking, skin-refining serum that protects, revitalises, moisturises and firms slackening skin in need of some TLC, with a 97% natural-origin formulation.”
Source: Mankind

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, helianthus annuus seed oil.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.3–2.8%
Hydroxypropyl tetrahydropyrantriolKey activeEffect: HighPro-Xylane, a sugar-derived molecule developed by L'Oréal. In lab and skin-model studies it prompts skin cells to make more glycosaminoglycans, the water-holding molecules of the dermis. Evidence in people comes almost only from L'Oréal's own multi-ingredient products.~1.9–2.4%
Caprylic/capric glyceridesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~0.95–1.15%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.65–0.95%
UndecaneKey active· EmollientEffect: MediumHelps create a non-greasy finish on the skin~0.45–0.7%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.7%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.4–0.65%
TrihydroxystearinKey activeEffect: MediumHelps soften the upper layer of the skin and improve the product texture~0.4–0.6%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.15–0.25%
Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~1.7–2.1%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~1.1–1.3%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.6–0.9%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.2%
Evens skin tone
Salicylic acid
Not delivered
What the product description says
“Applied to cleansed skin before moisturisers, the serum leaves skin plump, supple and smooth with visually significant improvements in skin texture, tone and radiance.”
Source: Mankind

This product might help improve the skin tone through exfoliation. In other words, it helps to speed up the shedding of cells from the upper layer of the skin, and this might help reduce hyperpigmentation.

Salicylic acidEffect: LowUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.35–0.65%
Exfoliation
Side benefit · Salicylic acid, Microcrystalline cellulose
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: salicylic acid.

Salicylic acidKey activeEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.35–0.65%
Microcrystalline celluloseEffect: Low~1.4–1.8%
Anti-blemish
Side benefit · Salicylic acid
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: salicylic acid. This ingredient is used for treating acne and can have a noticeable effect.

Salicylic acidHeroEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.35–0.65%

Can it cause trouble?

Irritancy
11 strong irritants: Tilia cordata flower water, Mentha piperita leaf water + 9 more — patch-test recommended
High risk
We flagged 21 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Tilia cordata flower water—High~7.1–8.7%est.
Mentha piperita leaf waterUsed as a fragrance and can be irritatingHigh~4.4–5.4%est.
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~3.5–4.2%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~1.1–1.3%est.
Rosmarinus officinalis leaf oilA plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skinHigh~0.55–0.85%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.5–0.8%est.
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.45–0.65%est.
LinaloolA fragrance. Can be irritatingHigh~0.35–0.6%est.
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~0.35–0.65%est.
Mentha piperita oilUsed as a fragrance and can be irritatingHigh~0.3–0.55%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.2–0.4%est.
Origanum majorana leaf oil—High~0.2–0.35%est.
FarnesolAdded to create a nice product smell. Can be irritatingHigh~0.1–0.2%est.
GeraniolA fragrance. Can be irritatingHigh~0.1–0.2%est.
CarrageenanHelps thicken the product formula and create a nice product formulationMedium~0.75–1.1%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.6–0.9%est.
Methyl glucose sesquistearateHelps water and oil mix togetherMedium~0.55–0.8%est.
UndecaneHelps create a non-greasy finish on the skinMedium~0.45–0.7%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.45–0.65%est.
TridecaneHelps create a dry, non-greasy finish of the skinMedium~0.3–0.6%est.
Dehydroacetic acidA preservativeMedium~0.15–0.25%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
CarrageenanHelps thicken the product formula and create a nice product formulation3/5~0.75–1.1%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Tilia cordata flower water~7.1–8.7%
Irritant · high
Mentha piperita leaf water~4.4–5.4%
Irritant · high
Irritation risk
High

Used as a fragrance and can be irritating

More about Mentha piperita leaf water
Alcohol denat.~3.5–4.2%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Propanediol~2.6–3.2%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Glycerin~2.3–2.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydroxypropyl tetrahydropyrantriol~1.9–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Pro-Xylane, a sugar-derived molecule developed by L'Oréal. In lab and skin-model studies it prompts skin cells to make more glycosaminoglycans, the water-holding molecules of the dermis. Evidence in people comes almost only from L'Oréal's own multi-ingredient products.

More about Hydroxypropyl tetrahydropyrantriol
Dicaprylyl ether~1.7–2.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether
Microcrystalline cellulose~1.4–1.8%
Formula
Irritation risk
Low
Works for
Exfoliation
More about Microcrystalline cellulose
Propylene glycol~1.1–1.3%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Caprylic/capric glycerides~0.95–1.15%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

Help soften the upper layer of the skin

More about Caprylic/capric glycerides
Carrageenan~0.75–1.1%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5

Helps thicken the product formula and create a nice product formulation

More about Carrageenan
Sodium hyaluronate~0.65–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Silica~0.95–1.2%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
Caprylyl glycol~0.6–0.9%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Rosmarinus officinalis leaf oil~0.55–0.85%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-oxidation

A plant oil with high content of volatile compounds that can irritate the skin. Can be used as a fragrance. Has anti-bacterial properties and might help neutralize free radicals on the surface of the skin

More about Rosmarinus officinalis leaf oil
Benzyl alcohol~0.5–0.8%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Cellulose~0.55–0.85%
Formula
Irritation risk
Low
Works for
Mattifying

Can be used to help absorb oil as well as add volume and imporve texture of products.

More about Cellulose
Cellulose gum~0.5–0.8%
Formula
Irritation risk
Low

Used to create thicker product consistency and stabilize emulsions

More about Cellulose gum
Methyl glucose sesquistearate~0.55–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Methyl glucose sesquistearate
Adenosine~0.45–0.7%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Xanthan gum~0.45–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Undecane~0.45–0.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps create a non-greasy finish on the skin

More about Undecane
Arginine~0.4–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Citric acid~0.45–0.65%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Lavandula angustifolia oil~0.45–0.65%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Candelilla cera~0.5–0.7%
Formula
Trihydroxystearin~0.4–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and improve the product texture

More about Trihydroxystearin
Linalool~0.35–0.6%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Tridecane~0.3–0.6%
Irritant · medium
Irritation risk
Medium

Helps create a dry, non-greasy finish of the skin

More about Tridecane
Salicylic acid~0.35–0.65%
Hero · Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-blemishExfoliationAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Mentha piperita oil~0.3–0.55%
Irritant · high
Irritation risk
High

Used as a fragrance and can be irritating

More about Mentha piperita oil
Fusanus spicatus wood oil~0.3–0.6%
Formula
Osmanthus fragrans flower extract~0.3–0.55%
Formula
Pogostemon cablin oil~0.25–0.45%
Formula
Limonene~0.2–0.4%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Origanum majorana leaf oil~0.2–0.35%
Irritant · high
Dehydroacetic acid~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Dehydroacetic acid
Farnesol~0.1–0.2%
Irritant · high
Irritation risk
High

Added to create a nice product smell. Can be irritating

More about Farnesol
Geraniol~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Tocopherol~0.1–0.2%
Formula
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Helianthus annuus seed oil~0.15–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Ingredient list view

Water, Tilia cordata flower water, Mentha piperita leaf water, Alcohol denat., Propanediol, Glycerin, Hydroxypropyl tetrahydropyrantriol, Dicaprylyl ether, Microcrystalline cellulose, Propylene glycol, Caprylic/capric glycerides, Carrageenan, Sodium hyaluronate, Silica, Caprylyl glycol, Rosmarinus officinalis leaf oil, Benzyl alcohol, Cellulose, Cellulose gum, Methyl glucose sesquistearate, Adenosine, Xanthan gum, Undecane, Arginine, Citric acid, Lavandula angustifolia oil, Candelilla cera, Trihydroxystearin, Linalool, Tridecane, Salicylic acid, Mentha piperita oil, Fusanus spicatus wood oil, Osmanthus fragrans flower extract, Pogostemon cablin oil, Limonene, Origanum majorana leaf oil, Dehydroacetic acid, Farnesol, Geraniol, Tocopherol, Helianthus annuus seed oil

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Amazon USPrice as of 11/14 09:20 GMT
$24.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
DECLEORAntidote SerumYOUR PRODUCTLa Roche-PosayPure Vitamin C Face SerumSanofloreSérum Magnifica Anti-Imperfections Global Corrector OrganicDr. Jart+Dermask Solution 1pc
Match—85%84%83%
Price$24.99$35.98+$10.99$39.42+$14.43$6.90−$18.09
Shared key ingredients—3 of 75 of 76 of 7
Key difference—Vitamin CLactic AcidNiacinamide
Irritancy High Medium High High
Drying alcohol Contains drying alcohol Contains drying alcohol Contains drying alcohol Contains drying alcohol
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Product summary

"DECLEOR - Antidote Serum" is effective for: Anti-aging

This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Adenosine 0.45% - 0.65%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
  • Humectants (glycerin 1.80% - 2.20%, sodium hyaluronate 0.60% - 0.85% and arginine 0.40% - 0.65%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails from 32.95£ up to 925.00£ in the United Kingdom and from 45.95$ up to 49.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 30 studies and safety reviews.

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