Darphin Predermine Wrinkle Repair Serum
Something wrong? Edit here- Anti-aging
- Moisturizing
- Evens skin tone
- acetyl glucosamine
- palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine
- arabidopsis thaliana extract
- +16 more
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Formula review
Promise
What does the product description say?WIMJ summary
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: arabidopsis thaliana extract, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
MEDIUM
| |||
MEDIUM
|
WIMJ summary
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycine soja protein.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
LOW
| |||
LOW
|
Promise
What does the product description say?WIMJ summary
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
faex, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
HIGH | |||
HIGH |
Potential irritants

Ingredient | Irritancy | Skin Benefit |
---|---|---|
caprylic/capric triglyceride | ||
steareth-2 | ||
steareth-21 |
Ingredients by volume
Ingredient | Estimated concentration |
---|---|
Plain old water
| 45% - 55% |
Helps to soften the upper layer of the skin and create a nice product texture
| 5.6% - 6.9% |
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
| 4% - 4.9% |
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Questions
Skincare resources
Scientific Sources
- Safety Assessment of Polyene Group as Used in Cosmetics
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- Glycerol and the skin: holistic approach to its origin and functions
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- Hibiscus sabdariffa L. – A phytochemical and pharmacological review
- Liposome-containing Hibiscus sabdariffa calyx extract formulations with increased antioxidant activity, improved dermal penetration and reduced dermal toxicity
- Repair of Damaged DNA by Arabidopsis Cell Extract
- Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel
- Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmetics
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
- Effect of topically applied lipids on surfactant-irritated skin
- Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries
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- Cosmetic and dermatologic use of alpha hydroxy acids
- Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma
- Benzophenone 4: An emerging allergen in cosmetics and toiletries?
- Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
- Dermatological and cosmeceutical benefits of Glycine max (soybean) and its active components
- Extracts from Glycine max (soybean) induce elastin synthesis and inhibit elastase activity
- The natural yeast extract isolated by ethanol precipitation inhibits melanin synthesis by modulating tyrosinase activity and downregulating melanosome transfer
- Evaluation of dermatological effects of cosmetic formulations containing Saccharomyces cerevisiae extract and vitamins
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Safety Assessment of Helianthus annuus (Sunflower)-Derived Ingredients as Used in Cosmetics
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- Glucosamine: an ingredient with skin and other benefits
- Genomic expression changes induced by topical N-acetyl glucosamine in skin equivalent cultures in vitro
- Incorporation of D-(^H)glucosamine into normal and psoriatic epidermal glycoconjugates
- Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine