Darphin - Predermine Sculpting Night Cream

Darphin Predermine Sculpting Night Cream

Efficacy100/100

Works for:

based on ingredients and %
  • Moisturizing
  • Anti-aging
  • Evens skin tone

Can it cause trouble?

  • Irritation risk: high
  • Comedogenic risk ingredients: 6

Key actives

Yeast extract0.25% - 0.45%Acetyl glucosamine0.25% - 0.45%Tocopherol0.2% - 0.4%
Price unavailable
Price as of Jun 1, 2026.
Amazon US
Price unavailable
Check price at Amazon US
Submit an edit
Cheaper Alternatives
Similar formulations, better price
This is the best value among similar products!

Product Summary

"Darphin - Predermine Sculpting Night Cream" has a good moisturizing formula. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (acetyl glucosamine, acetyl hexapeptide-8, diglycerin, faex and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, oryza sativa bran oil, theobroma cacao seed butter and butyrospermum parkii butter in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We like that this moisturizer contains peptides (palmitoyl hexapeptide-12 0.25% - 0.45%, acetyl hexapeptide-8 0.25% - 0.45%, palmitoyl tripeptide-5 0.25% - 0.45%, palmitoyl tripeptide-1 0.30% - 0.55% and palmitoyl tetrapeptide-7 0.30% - 0.55%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, tetrahexyldecyl ascorbate and yeast extract

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 57.15£ up to 105.00£ in the United Kingdom, for 190.43A$ in Australia and for 77.49$ in the United States.

For a detailed price comparison: click here.

Price unavailable
Amazon US