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Darphin Predermine Sculpting Night Cream
Darphin

Darphin Predermine Sculpting Night Cream

Efficacy100/100IrritancyHigh
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Works for

2 of 2 advertised claims delivered

Anti-aging
Palmitoyl hexapeptide-12, Acetyl glucosamine + 7 more
Strong evidence
What the product description says
“The moisturiser works overnight to support the skin’s regenerative system, lifting the facial contours and reducing the appearance of fine lines and wrinkles.”
Source: Lookfantastic

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine, palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~5.3–6.5%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.3–0.55%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.25–0.5%
Moisturizing
Palmitoyl hexapeptide-12, Acetyl glucosamine + 31 more
Strong evidence
What the product description says
“Enriched with Tuberose and time-released vitamins, the cream restores moisture and plumps the skin texture to allow you to wake up to a renewed, younger-looking complexion.”
Source: Lookfantastic

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: diglycerin, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, chondrus crispus extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8, palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.45–0.65%
Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Oryza sativa bran oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and might have some anti-oxidant properties~2.5–3%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.5%
Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~3.4–4.1%
Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Prunus amygdalus dulcis seed extractKey activeEffect: HighAlmond extract (oil) - helps soften the upper layer of the skin~0.25–0.45%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~5.3–6.5%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.6–0.9%
Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.25–0.5%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
DiglycerinKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.3–0.55%
Theobroma cacao seed butterKey active· EmollientEffect: HighHelps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect~1.4–1.8%
Gelidiella acerosa extractKey activeEffect: HighAn algae extract that can help attract water to the upper layer of the skin and have some anti-oxidant properties~0.25–0.45%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.25–0.45%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.4–0.65%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.3–0.55%
Glycine soja proteinKey active· Humectant, EmollientEffect: MediumA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.3–0.55%
Hydrogenated vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~0.95–1.15%
Hypnea musciformis extractKey active· HumectantEffect: MediumMight help to attract water to the upper layer of the skin~0.25–0.45%
Tribehenin· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~0.5–0.75%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~4.3–5.3%
Tridecyl trimellitate· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~0.7–1%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.1–2.5%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.55%
Peg-8· HumectantEffect: LowUsed to create a nice product consistency~0.25–0.5%
Propylene glycol dicaprate· EmollientEffect: LowAn emollient that helps soften the upper layer of the skin~0.3–0.55%
Glyceryl polymethacrylate· Humectant, EmollientEffect: LowUsed to create a nice product texture~0.3–0.55%
Yeast extractUnder-dosedEffect: HighHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.25–0.45%
Cucumis sativus fruit extractEffect: Low, below effective doseMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect~0.25–0.45%
Evens skin tone
Not advertised by the brand · Acetyl glucosamine, Glycine soja protein + 2 more
Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycine soja protein.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.3–0.55%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.25–0.5%
Yeast extractEffect: Low, below effective doseHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.25–0.45%

Can it cause trouble?

Irritancy
17 strong irritants: Hibiscus sabdariffa flower extract, Gelidiella acerosa extract + 15 more — patch-test recommended
High risk
We flagged 38 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Hibiscus sabdariffa flower extractA plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicalsHigh~0.25–0.5%est.
Gelidiella acerosa extractAn algae extract that can help attract water to the upper layer of the skin and have some anti-oxidant propertiesHigh~0.25–0.45%est.
Equisetum arvense extractA plant extract that might have anti-oxidant properties. Can be irritatingHigh~0.25–0.5%est.
Polianthes tuberosa polysaccharide—High~0.25–0.45%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.25–0.45%est.
Ethylhexyl methoxycinnamateOctinoxate. When used in higher concentrations, works as a sunscreen protecting the skin from UVB rays. When used in lower concentration, helps to preserve the product formulation. Is shown to be harmful to coral reefs - consider avoiding bathing in coral reef areas when wearing a product with this ingredient. It can be irritatingHigh~0.5–0.7%est.
Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.25–0.45%est.
Benzyl salicylateA fragrance. Is a likely irritantHigh~0.25–0.45%est.
Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.25–0.4%est.
Butylphenyl methylpropionalA fragrance. Can trigger allergic reactions and be irritatingHigh~0.25–0.45%est.
HydroxycitronellalA fragrance. A likely allergen and can be irritatingHigh~0.25–0.45%est.
CitronellolA fragrance. Can be irritatingHigh~0.25–0.45%est.
LinaloolA fragrance. Can be irritatingHigh~0.25–0.4%est.
Amyl cinnamal—High~0.2–0.4%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.2–0.4%est.
GeraniolA fragrance. Can be irritatingHigh~0.15–0.3%est.
CitralA fragrance with a lemon scent. A likely irritantHigh~0.15–0.25%est.
CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.15–0.3%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~3.4–4.1%est.
Tridecyl trimellitateUsed to create a thicker product consistency and soften the upper layer of the skinMedium~0.7–1%est.
Polyglyceryl-3 methylglucose distearateHelps water and oil mix togetherMedium~0.45–0.7%est.
Hordeum vulgare extractA plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to glutenMedium~0.3–0.55%est.
Cucumis sativus fruit extractMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effectMedium~0.25–0.45%est.
Ppg-26-buteth-26Helps oil and water mix togetherMedium~0.25–0.5%est.
CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.25–0.45%est.
EthylhexylglycerinA preservativeMedium~0.25–0.45%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.5%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.3–0.55%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.55%est.
Phytic acidAn alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmeticsMedium~0.25–0.5%est.
Peg-8Used to create a nice product consistencyMedium~0.25–0.5%est.
Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Medium~0.25–0.5%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.25–0.45%est.
Peg-40 hydrogenated castor oilHelps oil and water mix togetherMedium~0.3–0.55%est.
Butyl methoxydibenzoylmethaneAvobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.Medium~0.5–0.7%est.
Tetrasodium edtaHelps to stabilize the product formulationMedium~0.25–0.5%est.
BhtA preservativeMedium~0.25–0.5%est.
Ci 14700A colorantMedium~0.15–0.3%est.
Comedogenic
6 ingredients rated 2 or more on the 0–5 pore-clogging scale
6 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~5.3–6.5%est.
Theobroma cacao seed butterHelps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect3/5~1.4–1.8%est.
Hypnea musciformis extractMight help to attract water to the upper layer of the skin3/5~0.25–0.45%est.
Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.25–0.5%est.
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.3–0.55%est.
Hydrogenated vegetable oilAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin2/5~0.95–1.15%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Butyrospermum parkii butter~5.3–6.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Butylene glycol~4.3–5.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Simmondsia chinensis seed oil~3.4–4.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Oryza sativa bran oil~2.5–3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and might have some anti-oxidant properties

More about Oryza sativa bran oil
Glyceryl stearate~2.1–2.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~1.8–2.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Theobroma cacao seed butter~1.4–1.8%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-dandruff

Helps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect

More about Theobroma cacao seed butter
Propanediol~1.2–1.4%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Hydrogenated vegetable oil~0.95–1.15%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Hydrogenated vegetable oil
Tridecyl trimellitate~0.7–1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tridecyl trimellitate
Squalane~0.6–0.9%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Tribehenin~0.5–0.75%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tribehenin
Polyglyceryl-3 methylglucose distearate~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-3 methylglucose distearate
Triisostearin~0.35–0.65%
Formula
Irritation risk
Low
More about Triisostearin
Glycerin~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cetearyl olivate~0.4–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Cetyl alcohol~0.4–0.65%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Diglycerin~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Diglycerin
Menyanthes trifoliata leaf extract~0.25–0.5%
Formula
Irritation risk
Low
More about Menyanthes trifoliata leaf extract
Hibiscus sabdariffa flower extract~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals

More about Hibiscus sabdariffa flower extract
Hordeum vulgare extract~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten

More about Hordeum vulgare extract
Prunus amygdalus dulcis seed extract~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Almond extract (oil) - helps soften the upper layer of the skin

More about Prunus amygdalus dulcis seed extract
Gelidiella acerosa extract~0.25–0.45%
Key activeIrritant · high
Irritation risk
High
Works for
MoisturizingAnti-oxidation

An algae extract that can help attract water to the upper layer of the skin and have some anti-oxidant properties

More about Gelidiella acerosa extract
Hypnea musciformis extract~0.25–0.45%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Might help to attract water to the upper layer of the skin

More about Hypnea musciformis extract
Equisetum arvense extract~0.25–0.5%
Irritant · high
Irritation risk
High

A plant extract that might have anti-oxidant properties. Can be irritating

More about Equisetum arvense extract
Cucumis sativus fruit extract~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizing

Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect

More about Cucumis sativus fruit extract
Iris pallida root extract~0.2–0.4%
Formula
Irritation risk
Low
More about Iris pallida root extract
Palmitoyl tetrapeptide-7~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Iris florentina root extract~0.25–0.45%
Formula
Irritation risk
Low
More about Iris florentina root extract
Ppg-26-buteth-26~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Ppg-26-buteth-26
Acetyl glucosamine~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingEvens skin toneAnti-agingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Caffeine~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine
Glucose~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose
Palmitoyl tripeptide-1~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl tripeptide-5~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Oryza sativa bran extract~0.25–0.45%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Oryza sativa bran extract
Acetyl hexapeptide-8~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Ethylhexylglycerin~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Polianthes tuberosa polysaccharide~0.25–0.45%
Irritant · high
Irritation risk
High
More about Polianthes tuberosa polysaccharide
Chondrus crispus extract~0.25–0.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract
Yeast extract~0.25–0.45%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-oxidationReduces irritationAnti-inflammatoryEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin

More about Yeast extract
Propylene glycol dicaprate~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the upper layer of the skin

More about Propylene glycol dicaprate
Palmitoyl hexapeptide-12~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-agingMoisturizing

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12
Sorbitan olivate~0.3–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Glycine soja protein~0.3–0.55%
Key active
Irritation risk
Low
Works for
CleansingMoisturizingAnti-agingEvens skin toneAnti-oxidation

A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking

More about Glycine soja protein
Sodium hyaluronate~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Tocopheryl acetate~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Ethylhexyl palmitate~0.3–0.55%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Helianthus annuus seedcake~0.4–0.6%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Helianthus annuus seedcake
Glyceryl polymethacrylate~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture

More about Glyceryl polymethacrylate
Potassium cetyl phosphate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Caprylyl glycol~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Parfum~0.25–0.45%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Carbomer~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Cellulose gum~0.3–0.5%
Formula
Irritation risk
Low

Used to create thicker product consistency and stabilize emulsions

More about Cellulose gum
Polysorbate 20~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Phytic acid~0.25–0.5%
Irritant · medium
Irritation risk
Medium

An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics

More about Phytic acid
Peg-8~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a nice product consistency

More about Peg-8
Tetrahexyldecyl ascorbate~0.25–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneAnti-agingAnti-oxidation

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

More about Tetrahexyldecyl ascorbate
Hexylene glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Sodium hydroxide~0.25–0.5%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Peg-40 hydrogenated castor oil~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-40 hydrogenated castor oil
Dipropylene glycol~0.25–0.45%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Ethylhexyl methoxycinnamate~0.5–0.7%
Irritant · high
Irritation risk
High
Works for
Sun protection

Octinoxate. When used in higher concentrations, works as a sunscreen protecting the skin from UVB rays. When used in lower concentration, helps to preserve the product formulation. Is shown to be harmful to coral reefs - consider avoiding bathing in coral reef areas when wearing a product with this ingredient. It can be irritating

More about Ethylhexyl methoxycinnamate
Butyl methoxydibenzoylmethane~0.5–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Sun protection

Avobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.

More about Butyl methoxydibenzoylmethane
Ethylhexyl salicylate~0.5–0.7%
Formula
Irritation risk
Low
Works for
Sun protection

Octisalate. A UV filter. It offers some protection against the sun rays that cause sunburn (UVB), but does not protect against the most aging sun rays (UVA). It loses its effectiveness quickly when exposed to sunlight. It is an organic, or so called "chemical" sunscreen

More about Ethylhexyl salicylate
Xanthan gum~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Silica dimethyl silylate~0.3–0.55%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Silica dimethyl silylate
Tetrasodium edta~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Helps to stabilize the product formulation

More about Tetrasodium edta
Bht~0.25–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Phenoxyethanol~0.25–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Hexyl cinnamal~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal
Benzyl salicylate~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. Is a likely irritant

More about Benzyl salicylate
Alpha-isomethyl ionone~0.25–0.4%
Irritant · high
Irritation risk
High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone
Butylphenyl methylpropional~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. Can trigger allergic reactions and be irritating

More about Butylphenyl methylpropional
Hydroxycitronellal~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. A likely allergen and can be irritating

More about Hydroxycitronellal
Citronellol~0.25–0.45%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Linalool~0.25–0.4%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Amyl cinnamal~0.2–0.4%
Irritant · high
Irritation risk
High
More about Amyl cinnamal
Limonene~0.2–0.4%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Geraniol~0.15–0.3%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Citral~0.15–0.25%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
Coumarin~0.15–0.3%
Irritant · high
Irritation risk
High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin
Ci 14700~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A colorant

More about Ci 14700
Ci 60730~0.1–0.2%
Formula
Irritation risk
Low
More about Ci 60730
Ingredient list view

Water, Butyrospermum parkii butter, Butylene glycol, Simmondsia chinensis seed oil, Oryza sativa bran oil, Glyceryl stearate, Peg-100 stearate, Theobroma cacao seed butter, Propanediol, Hydrogenated vegetable oil, Tridecyl trimellitate, Squalane, Tribehenin, Polyglyceryl-3 methylglucose distearate, Triisostearin, Glycerin, Cetearyl olivate, Cetyl alcohol, Diglycerin, Menyanthes trifoliata leaf extract, Hibiscus sabdariffa flower extract, Hordeum vulgare extract, Prunus amygdalus dulcis seed extract, Gelidiella acerosa extract, Hypnea musciformis extract, Equisetum arvense extract, Cucumis sativus fruit extract, Iris pallida root extract, Palmitoyl tetrapeptide-7, Iris florentina root extract, Ppg-26-buteth-26, Acetyl glucosamine, Caffeine, Glucose, Palmitoyl tripeptide-1, Palmitoyl tripeptide-5, Oryza sativa bran extract, Acetyl hexapeptide-8, Ethylhexylglycerin, Polianthes tuberosa polysaccharide, Chondrus crispus extract, Yeast extract, Propylene glycol dicaprate, Palmitoyl hexapeptide-12, Sorbitan olivate, Glycine soja protein, Sodium hyaluronate, Tocopheryl acetate, Ethylhexyl palmitate, Helianthus annuus seedcake, Glyceryl polymethacrylate, Potassium cetyl phosphate, Caprylyl glycol, Parfum, Carbomer, Cellulose gum, Polysorbate 20, Phytic acid, Peg-8, Tetrahexyldecyl ascorbate, Hexylene glycol, Sodium hydroxide, Peg-40 hydrogenated castor oil, Dipropylene glycol, Ethylhexyl methoxycinnamate, Butyl methoxydibenzoylmethane, Ethylhexyl salicylate, Xanthan gum, Silica dimethyl silylate, Tetrasodium edta, Bht, Phenoxyethanol, Hexyl cinnamal, Benzyl salicylate, Alpha-isomethyl ionone, Butylphenyl methylpropional, Hydroxycitronellal, Citronellol, Linalool, Amyl cinnamal, Limonene, Geraniol, Citral, Coumarin, Ci 14700, Ci 60730

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Amazon USPrice as of 10/31/2026 03:19 GMT
$144.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
DarphinPredermine Sculpting Night CreamYOUR PRODUCTCliniqueSmart Clinical Repair™ Wrinkle Correcting Rich CreamPeter Thomas RothPeptide 21 Lift & Firm MoisturizerEyenlipSalmon Oil Nutrition Cream Mini
Match—56%53%51%
Price$140.69$64.31−$76.38$56.00−$84.69$4.50−$136.19
Shared key ingredients—9 of 219 of 217 of 21
Key difference—Acetyl Octapeptide-3Tripeptide-1Copper Tripeptide-1
Irritancy High Medium Medium Medium
Drying alcohol————
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Product summary

"Darphin - Predermine Sculpting Night Cream" has a good moisturizing formula. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (acetyl glucosamine, acetyl hexapeptide-8, diglycerin, faex and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, oryza sativa bran oil, theobroma cacao seed butter and butyrospermum parkii butter in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We like that this moisturizer contains peptides (palmitoyl hexapeptide-12 0.25% - 0.45%, acetyl hexapeptide-8 0.25% - 0.45%, palmitoyl tripeptide-5 0.25% - 0.45%, palmitoyl tripeptide-1 0.30% - 0.55% and palmitoyl tetrapeptide-7 0.30% - 0.55%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, tetrahexyldecyl ascorbate and yeast extract

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 57.15£ up to 105.00£ in the United Kingdom, for 190.43A$ in Australia and for 77.49$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 30 studies and safety reviews.

  1. 1
    Study on the Composition of Rice Bran Oil and Its Higher Free Fatty Acids Valuelink.springer.com
  2. 2
    Cocoa polyphenols and their influence on parameters involved in ex vivo skin restructuringncbi.nlm.nih.gov
  3. 3
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  4. 4
    Anthocyanin-rich extract from Hibiscus sabdariffa calyx counteracts UVC-caused impairments in ratsncbi.nlm.nih.gov
  5. 5
    Hibiscus sabdariffa L. – A phytochemical and pharmacological reviewsciencedirect.com
  6. 6
    Liposome-containing Hibiscus sabdariffa calyx extract formulations with increased antioxidant activity, improved dermal penetration and reduced dermal toxicityncbi.nlm.nih.gov
Darphin Predermine Sculpting Night Cream
DarphinPredermine Sculpting Night Cream
Buy on Amazon$144.99 · as of 10/31 03:19 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$144.99 · as of 10/31 03:19 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.