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Darphin Predermine Densifying Anti Wrinkle Cream
Darphin

Darphin Predermine Densifying Anti Wrinkle Cream

Efficacy100/100IrritancyHigh
See all ingredients

Works for

Moisturizing
Palmitoyl tetrapeptide-7, Acetyl glucosamine + 26 more
Works well
What the product description says
“Nourish and soothe the skin with Darphin Predermine Anti-Wrinkle Cream for Dry Skin, a sumptuous, rich moisturiser with a buttery texture that delivers an intense dose of hydration.”
Source: SpaceNK

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: algae extract, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, acetyl hexapeptide-8, palmitoyl tetrapeptide-7

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%
Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.3–5.2%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~4.3–5.3%
Macadamia ternifolia seed oilKey active· EmollientEffect: MediumPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients~1.6–2%
Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~1.3–1.5%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.75–1.1%
Glycine soja proteinKey active· Humectant, EmollientEffect: MediumA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.45–0.65%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.6%
Algae extractKey active· Humectant, EmollientEffect: HighPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.3–0.55%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.3–0.5%
Butyrospermum parkii butter unsaponifiablesKey activeEffect: HighA great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.25–0.45%
Chondrus crispusKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~0.25–0.45%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%
Coco-caprylate/caprateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin without creating a greasy texture~0.25–0.5%
GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.25–0.45%
Heptyl undecylenateKey active· Emollient, OcclusiveEffect: MediumHelps soften the upper layer of the skin, reduce water loss from the skin surface over time and create a nice product finish~0.25–0.5%
Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~3.1–3.7%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.95–1.15%
Arachidyl alcohol· EmollientEffect: LowUsed to soften the upper layer of the skin and create a thicker product consistency~0.3–0.5%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.3–0.55%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.3–0.55%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%
Propylene glycol dicaprate· EmollientEffect: LowAn emollient that helps soften the upper layer of the skin~0.25–0.5%
Padina pavonica thallus extractEffect: Low, below effective doseMight help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing~0.4–0.65%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.5%
Cucumis sativus fruit extractEffect: Low, below effective doseMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect~0.25–0.45%
Anti-aging
Arabidopsis thaliana extract, Palmitoyl tetrapeptide-7 + 5 more
Works well
What the product description says
“This deeply nourishing formula helps to strengthen the skin’s natural defences against dryness and works to plump skin with hyaluronic acid to help reduce the appearance of fine lines and wrinkles.”
Source: SpaceNK

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, arabidopsis thaliana extract, palmitoyl tetrapeptide-7.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Arabidopsis thaliana extractKey activeEffect: MediumPlant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking~0.45–0.7%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%
Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.75–1.1%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.45–0.65%
Algae extractEffect: LowPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.3–0.55%
Evens skin tone
Not advertised by the brand · Acetyl glucosamine, Glycine soja protein
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycine soja protein.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~0.25–0.45%
Glycine soja proteinEffect: LowA plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking~0.45–0.65%

Can it cause trouble?

Irritancy
16 strong irritants: Rosmarinus officinalis leaf extract, Equisetum arvense extract + 14 more — patch-test recommended
High risk
We flagged 39 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.35–0.65%est.
Equisetum arvense extractA plant extract that might have anti-oxidant properties. Can be irritatingHigh~0.3–0.5%est.
Hibiscus sabdariffa flower extractA plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicalsHigh~0.25–0.45%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.2–0.4%est.
Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.2–0.4%est.
LinaloolA fragrance. Can be irritatingHigh~0.2–0.4%est.
GeraniolA fragrance. Can be irritatingHigh~0.2–0.4%est.
Amyl cinnamal—High~0.2–0.4%est.
Benzyl salicylateA fragrance. Is a likely irritantHigh~0.2–0.4%est.
CitronellolA fragrance. Can be irritatingHigh~0.2–0.4%est.
CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.2–0.4%est.
HydroxycitronellalA fragrance. A likely allergen and can be irritatingHigh~0.2–0.4%est.
Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.2–0.35%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.2–0.35%est.
CitralA fragrance with a lemon scent. A likely irritantHigh~0.2–0.35%est.
Benzophenone-4Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritatingHigh~0.25–0.5%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~4.3–5.2%est.
Methyl glucose sesquistearateHelps water and oil mix togetherMedium~1.9–2.4%est.
Macadamia ternifolia seed oilPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredientsMedium~1.6–2%est.
Polyglyceryl-6 behenateHelps oil and water mix togetherMedium~1.4–1.8%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~1.3–1.5%est.
Arabidopsis thaliana extractPlant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lackingMedium~0.45–0.7%est.
Hordeum vulgare extractA plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to glutenMedium~0.3–0.55%est.
Cucumis sativus fruit extractMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effectMedium~0.25–0.45%est.
CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.25–0.45%est.
Sigesbeckia orientalis extractA plant extract that can contain an anti-inflammatory compoundMedium~0.2–0.4%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.
EthylhexylglycerinA preservativeMedium~0.25–0.45%est.
Diethylhexyl syringylidenemalonateUsed to stabilize the product formulationMedium~0.25–0.45%est.
Heptyl undecylenateHelps soften the upper layer of the skin, reduce water loss from the skin surface over time and create a nice product finishMedium~0.25–0.5%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.25–0.5%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.25–0.45%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.25–0.5%est.
Calcium chlorideHelps create a thicker product consistency. Might be irritatingMedium~0.25–0.45%est.
Tetrasodium edtaHelps to stabilize the product formulationMedium~0.2–0.35%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.2–0.35%est.
ChlorphenesinA preservativeMedium~0.15–0.25%est.
Potassium sorbateA preservativeMedium~0.15–0.3%est.
Ci 14700A colorantMedium~0.1–0.15%est.
Comedogenic
7 ingredients rated 2 or more on the 0–5 pore-clogging scale
7 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.75–1.1%est.
Padina pavonica thallus extractMight help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing3/5~0.4–0.65%est.
Algae extractPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet3/5~0.3–0.55%est.
Chondrus crispusRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~0.25–0.45%est.
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.3–0.5%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~4.3–5.3%est.
Butyrospermum parkii butter unsaponifiablesA great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals2/5~0.25–0.45%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glyceryl stearate se~4.3–5.3%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Caprylic/capric triglyceride~4.3–5.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Hydrogenated polydecene~3.1–3.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene
Propanediol~2.3–2.8%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Methyl glucose sesquistearate~1.9–2.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Methyl glucose sesquistearate
Macadamia ternifolia seed oil~1.6–2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

More about Macadamia ternifolia seed oil
Polyglyceryl-6 behenate~1.4–1.8%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Polyglyceryl-6 behenate
Simmondsia chinensis seed oil~1.3–1.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Butylene glycol~0.95–1.15%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Butyrospermum parkii butter~0.75–1.1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Iris florentina root extract~0.55–0.8%
Formula
Irritation risk
Low
More about Iris florentina root extract
Oryza sativa bran extract~0.5–0.75%
Formula
Irritation risk
Low

Used to thicken the product consistency

More about Oryza sativa bran extract
Arabidopsis thaliana extract~0.45–0.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-aging

Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking

More about Arabidopsis thaliana extract
Padina pavonica thallus extract~0.4–0.65%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

Might help to soften the upper layer of the skin. Is claimed to have anti-oxidant properties, but evidence in missing

More about Padina pavonica thallus extract
Rosmarinus officinalis leaf extract~0.35–0.65%
Irritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Glycine soja protein~0.45–0.65%
Key active
Irritation risk
Low
Works for
CleansingMoisturizingEvens skin toneAnti-agingAnti-oxidation

A plant extract that helps to attract water to the upper layer of the skin and soften it. It might be helpful in neutralizing free radicals. It might be somewhat helpful for evening out the skin tone. It might be able to support elastin production but solid research is lacking

More about Glycine soja protein
Menyanthes trifoliata leaf extract~0.3–0.6%
Formula
Irritation risk
Low
More about Menyanthes trifoliata leaf extract
Helianthus annuus seed extract~0.3–0.55%
Formula
Irritation risk
Low
More about Helianthus annuus seed extract
Helianthus annuus seed oil~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Hordeum vulgare extract~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten

More about Hordeum vulgare extract
Equisetum arvense extract~0.3–0.5%
Irritant · high
Irritation risk
High

A plant extract that might have anti-oxidant properties. Can be irritating

More about Equisetum arvense extract
Cucumis sativus fruit extract~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizing

Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect

More about Cucumis sativus fruit extract
Hibiscus sabdariffa flower extract~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals

More about Hibiscus sabdariffa flower extract
Algae extract~0.3–0.55%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-aging

Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet

More about Algae extract
Caffeine~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine
Sigesbeckia orientalis extract~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatory

A plant extract that can contain an anti-inflammatory compound

More about Sigesbeckia orientalis extract
Butyrospermum parkii butter unsaponifiables~0.25–0.45%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
MoisturizingAnti-oxidation

A great moisturizing ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter unsaponifiables
Chondrus crispus~0.25–0.45%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus
Acetyl glucosamine~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Caprylyl glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ethylhexyl palmitate~0.3–0.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Propylene glycol dicaprate~0.25–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the upper layer of the skin

More about Propylene glycol dicaprate
Ethylhexylglycerin~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Acetyl hexapeptide-8~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Arachidyl glucoside~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Arachidyl glucoside
Palmitoyl tetrapeptide-7~0.3–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Diethylhexyl syringylidenemalonate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Used to stabilize the product formulation

More about Diethylhexyl syringylidenemalonate
Heptyl undecylenate~0.25–0.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin, reduce water loss from the skin surface over time and create a nice product finish

More about Heptyl undecylenate
Glucose~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose
Coco-caprylate/caprate~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin without creating a greasy texture

More about Coco-caprylate/caprate
Palmitoyl tetrapeptide-10~0.25–0.45%
Formula
Irritation risk
Low
More about Palmitoyl tetrapeptide-10
Sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Arachidyl alcohol~0.3–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to soften the upper layer of the skin and create a thicker product consistency

More about Arachidyl alcohol
Acrylates/c10-30 alkyl acrylate crosspolymer~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Glyceryl stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Hexylene glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Lecithin~0.3–0.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Beheneth-25~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing
More about Beheneth-25
Potassium cetyl phosphate~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Potassium stearate~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing
More about Potassium stearate
Polysorbate 20~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Calcium chloride~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Helps create a thicker product consistency. Might be irritating

More about Calcium chloride
Behenyl alcohol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Carbomer~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Sodium hydroxide~0.25–0.45%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Parfum~0.2–0.4%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Alpha-isomethyl ionone~0.2–0.4%
Irritant · high
Irritation risk
High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone
Linalool~0.2–0.4%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Geraniol~0.2–0.4%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Amyl cinnamal~0.2–0.4%
Irritant · high
Irritation risk
High
More about Amyl cinnamal
Benzyl salicylate~0.2–0.4%
Irritant · high
Irritation risk
High

A fragrance. Is a likely irritant

More about Benzyl salicylate
Citronellol~0.2–0.4%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Coumarin~0.2–0.4%
Irritant · high
Irritation risk
High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin
Hydroxycitronellal~0.2–0.4%
Irritant · high
Irritation risk
High

A fragrance. A likely allergen and can be irritating

More about Hydroxycitronellal
Hexyl cinnamal~0.2–0.35%
Irritant · high
Irritation risk
High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal
Limonene~0.2–0.35%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Citral~0.2–0.35%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
Tetrasodium edta~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Helps to stabilize the product formulation

More about Tetrasodium edta
Silica dimethyl silylate~0.25–0.4%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Silica dimethyl silylate
Tocopheryl acetate~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Benzophenone-4~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Sun protection

Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritating

More about Benzophenone-4
Chlorphenesin~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Potassium sorbate~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ci 14700~0.1–0.15%
Irritant · medium
Irritation risk
Medium

A colorant

More about Ci 14700
Ingredient list view

Water, Glyceryl stearate se, Caprylic/capric triglyceride, Hydrogenated polydecene, Propanediol, Methyl glucose sesquistearate, Macadamia ternifolia seed oil, Polyglyceryl-6 behenate, Simmondsia chinensis seed oil, Butylene glycol, Butyrospermum parkii butter, Iris florentina root extract, Oryza sativa bran extract, Arabidopsis thaliana extract, Padina pavonica thallus extract, Rosmarinus officinalis leaf extract, Glycine soja protein, Menyanthes trifoliata leaf extract, Helianthus annuus seed extract, Helianthus annuus seed oil, Hordeum vulgare extract, Equisetum arvense extract, Cucumis sativus fruit extract, Hibiscus sabdariffa flower extract, Algae extract, Caffeine, Sigesbeckia orientalis extract, Butyrospermum parkii butter unsaponifiables, Chondrus crispus, Acetyl glucosamine, Caprylyl glycol, Ethylhexyl palmitate, Propylene glycol dicaprate, Ethylhexylglycerin, Acetyl hexapeptide-8, Arachidyl glucoside, Palmitoyl tetrapeptide-7, Diethylhexyl syringylidenemalonate, Heptyl undecylenate, Glucose, Coco-caprylate/caprate, Palmitoyl tetrapeptide-10, Sodium hyaluronate, Arachidyl alcohol, Acrylates/c10-30 alkyl acrylate crosspolymer, Glyceryl stearate, Peg-100 stearate, Hexylene glycol, Lecithin, Beheneth-25, Potassium cetyl phosphate, Potassium stearate, Polysorbate 20, Calcium chloride, Behenyl alcohol, Xanthan gum, Carbomer, Sodium hydroxide, Parfum, Alpha-isomethyl ionone, Linalool, Geraniol, Amyl cinnamal, Benzyl salicylate, Citronellol, Coumarin, Hydroxycitronellal, Hexyl cinnamal, Limonene, Citral, Tetrasodium edta, Silica dimethyl silylate, Tocopheryl acetate, Benzophenone-4, Chlorphenesin, Potassium sorbate, Phenoxyethanol, Ci 14700

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
DarphinPredermine Densifying Anti Wrinkle CreamYOUR PRODUCTCliniqueSmart Clinical Repair Wrinkle Cream RichLab Series Skincare for MenAnti-Age Max CreamPerricone MDCold Plasma Plus+ The Intensive Hydrating Complex
Match—56%53%52%
Price—$58.50$88.87$7.00
Shared key ingredients—7 of 155 of 156 of 15
Key difference—Acetyl Octapeptide-3NiacinamideAcetyl Tetrapeptide-9
Irritancy High Medium Medium Medium
Drying alcohol————
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Product summary

"Darphin - Predermine Densifying Anti Wrinkle Cream" has a good moisturizing formula. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (algae extract, glycerin, sodium hyaluronate, glucose and glycine soja protein) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Algae extract, caprylic/capric triglyceride, dimethicone, helianthus annuus seed oil and ethylhexyl palmitate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • This moisturizer also contains Peptides (palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine 0.80% - 1.20%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: lecithin, benzophenone-4, vitamin e, jojoba oil and butyrospermum parkii butter

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 88.92$ up to 158.00$ in the United States, for 331.58A$ in Australia and from 81.70£ up to 127.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 30 studies and safety reviews.

  1. 1
    Safety Assessment of Polyene Group as Used in Cosmeticscir-safety.org
  2. 2
    Fatty acids profile of oil from nine varieties of Macadamia nuttandfonline.com
  3. 3
    Repair of Damaged DNA by Arabidopsis Cell Extractncbi.nlm.nih.gov
  4. 4
    Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gelpubmed.ncbi.nlm.nih.gov
  5. 5
    Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmeticsjournals.sagepub.com
  6. 6
    Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responsesliebertpub.com
Darphin Predermine Densifying Anti Wrinkle Cream
DarphinPredermine Densifying Anti Wrinkle Cream
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