CosMedix Harmonize Microbiome Boosting Moisturizer

CosMedix Harmonize Microbiome Boosting Moisturizer

Efficacy100/100IrritancyHigh

Works for

Moisturizing
Panthenol, Glycerin + 14 more
Works well
What the product description says
“Harmonize Microbiome Boosting Moisturizer”
Source: Cosmedix

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, tremella fuciformis sporocarp extract.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.25–0.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.4–5.3%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.2–5.2%
Hydrogenated ethylhexyl olivateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~1.9–2.4%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.5–1.8%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.2–1.5%
Mangifera indica seed butterKey activeEffect: HighHelps to soften the upper layer of the skin and might have some anti-oxidant effect~0.9–1.1%
Vitis vinifera fruit extractKey activeEffect: MediumA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds~0.65–0.95%
Chlorella vulgaris extractKey activeEffect: MediumA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.45–0.65%
Ganoderma lucidum extractKey activeEffect: HighHelps attract water to the upper layer of the skin~0.4–0.6%
Tremella fuciformis sporocarp extractKey active· HumectantEffect: HighMushroom extract that helps attract water to the upper layer of the skin~0.25–0.5%
Hydrogenated olive oil unsaponifiablesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~0.25–0.45%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~3.1–3.8%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.3–2.8%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.45%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.1–0.25%

Can it cause trouble?

Irritancy
5 strong irritants: Zingiber officinale root extract, Withania somnifera root extract + 3 more — patch-test recommended
High risk
We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Zingiber officinale root extractA plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lackingHigh~0.55–0.8%est.
Withania somnifera root extract—High~0.3–0.6%est.
Lavandula angustifolia flower extractEssential oil that can be irritatingHigh~0.25–0.5%est.
CoumarinA fragrance. Is a likely skin allergen and can be irritatingHigh~0.05–0.1%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.1%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~4.2–5.2%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~3.1–3.8%est.
Vitis vinifera fruit extractA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seedsMedium~0.65–0.95%est.
Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory propertiesMedium~0.45–0.65%est.
Ganoderma lucidum extractHelps attract water to the upper layer of the skinMedium~0.4–0.6%est.
Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.3–0.55%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.25–0.45%est.
Sodium stearoyl lactylateHelps oil and water mix togetherMedium~0.25–0.45%est.
1,2-hexanediolA preservativeMedium~0.25–0.4%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.45%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.25%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.1–0.25%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties3/5~0.45–0.65%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.2–1.5%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.4–5.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Caprylic/capric triglyceride~4.2–5.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Pentylene glycol~3.1–3.8%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Glyceryl stearate~2.3–2.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Hydrogenated ethylhexyl olivate~1.9–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Hydrogenated ethylhexyl olivate
Lactobacillus ferment lysate filtrate~1.6–1.9%
Formula
Squalane~1.5–1.8%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Cetearyl alcohol~1.2–1.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Mangifera indica seed butter~0.9–1.1%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Helps to soften the upper layer of the skin and might have some anti-oxidant effect

More about Mangifera indica seed butter
Vitis vinifera fruit extract~0.65–0.95%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds

More about Vitis vinifera fruit extract
Zingiber officinale root extract~0.55–0.8%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking

More about Zingiber officinale root extract
Boswellia serrata extract~0.5–0.75%
Formula
Chlorella vulgaris extract~0.45–0.65%
Key activeComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
MoisturizingAnti-inflammatoryAnti-oxidation

A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties

More about Chlorella vulgaris extract
Rhodiola rosea root extract~0.45–0.7%
Formula
Inonotus obliquus extract~0.4–0.6%
Formula
Ganoderma lucidum extract~0.4–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Ganoderma lucidum extract
Withania somnifera root extract~0.3–0.6%
Irritant · high
Leuconostoc/radish root ferment filtrate~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate
Populus tremuloides bark extract~0.3–0.55%
Formula
Tremella fuciformis sporocarp extract~0.25–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Mushroom extract that helps attract water to the upper layer of the skin

More about Tremella fuciformis sporocarp extract
Panthenol~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Bisabolol~0.2–0.4%
Formula
Irritation risk
Low
Works for
Reduces irritationAnti-inflammatoryAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Hydroxyacetophenone~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Ammonium acryloyldimethyltaurate/vp copolymer~0.25–0.45%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Sodium stearoyl lactylate~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl lactylate
1,2-hexanediol~0.25–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Caprylyl glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sodium hydroxide~0.2–0.4%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Hydrogenated olive oil unsaponifiables~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Help soften the upper layer of the skin

More about Hydrogenated olive oil unsaponifiables
Propanediol~0.2–0.4%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Lavandula angustifolia flower extract~0.25–0.5%
Irritant · high
Irritation risk
High

Essential oil that can be irritating

More about Lavandula angustifolia flower extract
Sodium phytate~0.15–0.3%
Formula
Irritation risk
Low

Used to stabilize product formulations

More about Sodium phytate
Citric acid~0.15–0.25%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Lactic acid~0.1–0.25%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Coumarin~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Is a likely skin allergen and can be irritating

More about Coumarin
Linalool~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Ingredient list view

Water, Glycerin, Caprylic/capric triglyceride, Pentylene glycol, Glyceryl stearate, Hydrogenated ethylhexyl olivate, Lactobacillus ferment lysate filtrate, Squalane, Cetearyl alcohol, Mangifera indica seed butter, Vitis vinifera fruit extract, Zingiber officinale root extract, Boswellia serrata extract, Chlorella vulgaris extract, Rhodiola rosea root extract, Inonotus obliquus extract, Ganoderma lucidum extract, Withania somnifera root extract, Leuconostoc/radish root ferment filtrate, Populus tremuloides bark extract, Tremella fuciformis sporocarp extract, Panthenol, Bisabolol, Xanthan gum, Hydroxyacetophenone, Ammonium acryloyldimethyltaurate/vp copolymer, Sodium stearoyl lactylate, 1,2-hexanediol, Caprylyl glycol, Sodium hydroxide, Hydrogenated olive oil unsaponifiables, Propanediol, Lavandula angustifolia flower extract, Sodium phytate, Citric acid, Lactic acid, Sodium benzoate, Coumarin, Linalool

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Amazon USPrice as of 11/13 15:00 GMT
$71.00
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Cosmedix
$71.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
CosMedixHarmonize Microbiome Boosting MoisturizerYOUR PRODUCTAbibYesStyle Exclusive PDRN Volume Fill-it Booster Crème 2.5 Tube Mini 5pcs Bundle SetBonjourEGF Time Recovery Solution CreamThe Body ShopAloe Soothing Night Cream
Match—65%65%64%
Price$71.00$37.53−$33.47$43.20−$27.80$18.24−$52.76
Shared key ingredients—5 of 85 of 84 of 8
Key difference—Copper Tripeptide-1BakuchiolButyrospermum Parkii Butter
Irritancy High Medium Medium Low
Drying alcohol————
View product Shop Shop Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

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CosMedix Harmonize Microbiome Boosting Moisturizer
CosMedixHarmonize Microbiome Boosting Moisturizer

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.