CosMedix Defy

CosMedix Defy

Efficacy87/100IrritancyHigh

Works for

Exfoliation
Lactic acid, Tartaric acid + 1 more
Works well
What the product description says
“Overnight this exfoliator promotes cell turnover to slough away dull, dead skin cells and reveal smooth, soft ones.”
Source: Dermstore

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: lactic acid.

Lactic acidKey activeEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~4.3–6.4%
Tartaric acidKey activeEffect: MediumAn AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levels~0.95–1.45%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.65%
Evens skin tone
Lactic acid
Works well
What the product description says
“Uneven skin tone and texture improve to reveal a smoother, more youthful complexion.”
Source: Dermstore

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: lactic acid

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Lactic acidKey activeEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~4.3–6.4%
Anti-aging
Lactic acid, Prunus amygdalus dulcis oil + 1 more
May help
What the product description says
“Uneven skin tone and texture improve to reveal a smoother, more youthful complexion.”
Source: Dermstore

This product contains lactic acid. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Lactic acidKey activeEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~4.3–6.4%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.3–0.75%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–1%
Moisturizing
Lactic acid, Glycerin + 10 more
Works
What the product description says
“Gentle enough for sensitive skin, this reparative treatment provides comforting moisture coupled with extensive exfoliation.”
Source: Dermstore

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin, lactic acid.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

Lactic acidKey active· HumectantEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~4.3–6.4%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.6–3.9%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.7–2.6%
Tartaric acidKey activeEffect: MediumAn AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levels~0.95–1.45%
Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.5–1.15%
Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~0.3–0.75%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~3–4.6%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~1.5–2.3%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–1%
Aloe barbadensis leaf extractEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.4–0.9%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.2–0.8%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.65%
Anti-oxidation
Side benefit · Tartaric acid, Prunus amygdalus dulcis oil + 2 more
May help

This product contains antioxidants (tartaric acid) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Tartaric acidKey activeEffect: MediumAn AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levels~0.95–1.45%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.3–0.75%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.1–0.45%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–1%

Can it cause trouble?

Irritancy
3 strong irritants: Hamamelis virginiana extract, Citrus grandis peel oil + 1 more — patch-test recommended
High risk
We flagged 8 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Hamamelis virginiana extractA plant extract that can help calm down inflammation in skin. Can, however, itself be irritatingHigh~0.8–1.2%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.05–0.25%est.
Citrus grandis peel oilA plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skinHigh~0.05–0.2%est.
Cananga odorata flower oilAn essential oil. Can be irritatingHigh~0.05–0.15%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~4.3–6.4%est.
Tartaric acidAn AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levelsMedium~0.95–1.45%est.
Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.5–1.15%est.
Aloe barbadensis leaf extractTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.4–0.9%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Lactic acid~4.3–6.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Glyceryl stearate~3–4.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Glycerin~2.6–3.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Albumen~2.1–3.2%
Formula
Irritation risk
Low
More about Albumen
Cetyl alcohol~1.7–2.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Stearic acid~1.5–2.3%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Malic acid~1.2–1.8%
Formula
Irritation risk
Low

Helps adjust the product pH

More about Malic acid
Tartaric acid~0.95–1.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationExfoliation

An AHA (alpha-hydroxy acid). It oxidizes quickly which makes it less effective in skincare formulations. It can support skin's barrier and moisture levels

More about Tartaric acid
Hamamelis virginiana extract~0.8–1.2%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating

More about Hamamelis virginiana extract
Olea europaea fruit oil~0.5–1.15%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil
Tocopherol~0.4–1%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingMoisturizingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Aloe barbadensis leaf extract~0.4–0.9%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf extract
Prunus amygdalus dulcis oil~0.3–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil
Allantoin~0.15–0.65%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Lecithin~0.2–0.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Bisabolol~0.1–0.45%
Formula
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Benzyl alcohol~0.05–0.25%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Fullersomes
Not recognized
Citrus grandis peel oil~0.05–0.2%
Irritant · high
Irritation risk
High

A plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skin

More about Citrus grandis peel oil
Cananga odorata flower oil~0.05–0.15%
Irritant · high
Irritation risk
High

An essential oil. Can be irritating

More about Cananga odorata flower oil
Prunus persica kernel oil~0.05–0.25%
Formula
Ingredient list view

Water, Lactic acid, Glyceryl stearate, Glycerin, Albumen, Cetyl alcohol, Stearic acid, Malic acid, Tartaric acid, Hamamelis virginiana extract, Olea europaea fruit oil, Tocopherol, Aloe barbadensis leaf extract, Prunus amygdalus dulcis oil, Allantoin, Lecithin, Bisabolol, Benzyl alcohol, Unknown, Citrus grandis peel oil, Cananga odorata flower oil, Prunus persica kernel oil

Compare prices

Retailers ranked by price — lowest first.

Dermstore1.7 oz
$80.00 Out of stock
Check

Affiliate links

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
CosMedixDefyYOUR PRODUCTZO Skin HealthExfoliation AcceleratorHerbivoreMilky Way Sérum Exfoliant 10% Acide LactiqueHerbivore BotanicalsMilky Way 10% AHA + Oat Soothing Exfoliating Serum
Match—63%62%62%
Price—$70.00——
Shared key ingredients—2 of 64 of 64 of 6
Key difference—Retinyl PalmitateGluconolactoneGluconolactone
Irritancy High Medium Medium Medium
Drying alcohol————
View product Shop Shop Shop

More alternatives: Glo Skin Beauty Hydra-Bright Pro 5 Liquid ExfoliantClinique Clarifying Do-Over Peel

Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
CosMedix Defy
CosMedixDefy

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.