Clinique Dramatically Different Moisturizing Cream

Clinique Dramatically Different Moisturizing Cream

Efficacy75/100IrritancyLow
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Works for

1 of 2 advertised claims delivered

Moisturizing
Petrolatum, Glycerin + 11 more
Strong evidence
What the product description says
“Dramatically Different Moisturizing Cream”
Source: Clinique

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetyl alcohol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: petrolatum

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~5.6–6.8%
PetrolatumHero· Emollient, OcclusiveEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~3.4–4.2%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.55%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~4.8–5.8%
Dipentaerythrityl hexacaprylate/hexacaprateKey activeEffect: Medium~0.75–1.1%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.1–1.4%
Tridecyl trimellitate· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~2.1–2.6%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.25–0.5%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.5–0.75%
Propylene glycol dicaprate· EmollientEffect: LowAn emollient that helps soften the upper layer of the skin~0.5–0.75%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~1.6–2%
Tridecyl stearate· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~2.6–3.1%
Cucumis sativus fruit extractEffect: Low, below effective doseMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect~0.6–0.9%
Anti-aging
No ingredient credited for this claim
Limited evidence
What the product description says
“Use it daily to help keep skin looking younger, longer”
Source: Ulta

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.

Can it cause trouble?

Irritancy
9 flagged ingredients
Low risk
We flag 9 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Ci 19140A yellow dyeHigh~0.15–0.3%est.
Ci 15985A colorantHigh~0.15–0.25%est.
Tridecyl stearateUsed to create a thicker product consistency and soften the upper layer of the skinMedium~2.6–3.1%est.
Tridecyl trimellitateUsed to create a thicker product consistency and soften the upper layer of the skinMedium~2.1–2.6%est.
Cucumis sativus fruit extractMight be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effectMedium~0.6–0.9%est.
Hordeum vulgare extractA plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to glutenMedium~0.6–0.9%est.
Sodium stearoyl lactylateHelps oil and water mix togetherMedium~0.5–0.75%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.5–0.75%est.
Ci 17200A red colorantMedium~0.1–0.2%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~5.6–6.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~4.8–5.8%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Petrolatum~3.4–4.2%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Tridecyl stearate~2.6–3.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tridecyl stearate
Tridecyl trimellitate~2.1–2.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tridecyl trimellitate
Polyglyceryl-10 pentastearate~1.7–2.1%
Formula
Behenyl alcohol~1.6–2%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Peg-100 stearate~1.4–1.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Cetyl alcohol~1.1–1.4%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Dipentaerythrityl hexacaprylate/hexacaprate~0.75–1.1%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing
More about Dipentaerythrityl hexacaprylate/hexacaprate
Cucumis sativus fruit extract~0.6–0.9%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect

More about Cucumis sativus fruit extract
Hordeum vulgare extract~0.6–0.9%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties. Avoid if you are sensitive to gluten

More about Hordeum vulgare extract
Sodium stearoyl lactylate~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl lactylate
Caprylyl glycol~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Propylene glycol dicaprate~0.5–0.75%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the upper layer of the skin

More about Propylene glycol dicaprate
Helianthus annuus seed extract~0.35–0.65%
Formula
Sodium hyaluronate~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Butylene glycol~0.25–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Tromethamine~0.25–0.5%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Carbomer~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Phenoxyethanol~0.2–0.35%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ci 19140~0.15–0.3%
Irritant · high
Irritation risk
High

A yellow dye

More about Ci 19140
Ci 15985~0.15–0.25%
Irritant · high
Irritation risk
High

A colorant

More about Ci 15985
Ci 17200~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A red colorant

More about Ci 17200
Ingredient list view

Water, Glycerin, Dimethicone, Petrolatum, Tridecyl stearate, Tridecyl trimellitate, Polyglyceryl-10 pentastearate, Behenyl alcohol, Peg-100 stearate, Cetyl alcohol, Dipentaerythrityl hexacaprylate/hexacaprate, Cucumis sativus fruit extract, Hordeum vulgare extract, Sodium stearoyl lactylate, Caprylyl glycol, Propylene glycol dicaprate, Helianthus annuus seed extract, Sodium hyaluronate, Butylene glycol, Tromethamine, Carbomer, Phenoxyethanol, Ci 19140, Ci 15985, Ci 17200

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Bluemercury
$34.00
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Amazon USPrice as of 10/22/2026 03:10 GMT
$34.00
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Clinique
$34.00
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Sephora
$34.00
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Ulta
$34.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
CliniqueDramatically Different Moisturizing CreamYOUR PRODUCTolive manonShikolive Skin CreamCeraVeMoisturizing CreamCetaphilHydrating Night Cream
Match—64%62%62%
Price$34.00$14.60−$19.40$5.35−$28.65$1.32−$32.68
Shared key ingredients—4 of 44 of 43 of 4
Key difference—SqualaneCeramide EopNiacinamide
Irritancy Low Low Low Low
Drying alcohol————
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Product summary

"Clinique - Dramatically Different Moisturizing Cream" has a good moisturizing formula. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (glycerin, sodium hyaluronate, butylene glycol and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Petrolatum, dimethicone, cetyl alcohol, caprylyl glycol and propylene glycol dicaprate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 29.15$ up to 32.50$ in the United States, for 61.65CA$ in Canada, for 52.00A$ in Australia and for 19.95£ in the United Kingdom.

For a detailed price comparison: click here.

Clinique Dramatically Different Moisturizing Cream
CliniqueDramatically Different Moisturizing Cream

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As an Amazon Associate, WIMJ earns from qualifying purchases.