Biossance Squalane + Ectoin Overnight Rescue

Biossance Squalane + Ectoin Overnight Rescue

Efficacy87/100IrritancyLow
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Works for

2 of 2 advertised claims delivered

Moisturizing
12 ingredients credited for this claim
Strong support
What the product description says
“Wake up to renewed skin with our most intensive nighttime repair cream that goes beyond moisture to improve skin's self-defense capabilities, fight free radicals, and plump fine lines.”
Source: N/A

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, caprylyl glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.8–1.2%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~1.1–1.7%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–5.9%
Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~1–1.5%
Shorea stenoptera seed butterKey active· EmollientEffect: HighHelps soften the upper layer of the skin and can be helpful in restoring the skin barrier function~2.7–4.1%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~3.7–5.5%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.1–3.2%
C12-16 alcohols· EmollientEffect: LowHelps soften the upper layer of the skin and improve the product's texture~1.6–2.4%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.4%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.45–1.05%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.45%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.75%
Anti-aging
2 ingredients credited for this claim
Moderate support
What the product description says
“Wake up to renewed skin with our most intensive nighttime repair cream that goes beyond moisture to improve skin's self-defense capabilities, fight free radicals, and plump fine lines.”
Source: N/A

This product contains acetyl hexapeptide-8. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.8–1.2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.45%

Can it cause trouble?

Irritancy
7 flagged ingredients
Low risk
We flag 7 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.1–3.2%est.
C12-16 alcoholsHelps soften the upper layer of the skin and improve the product's textureMedium~1.6–2.4%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~1.2–1.8%est.
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~1–1.5%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.2–0.75%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.4%est.
EthylhexylglycerinA preservativeMedium~0.05–0.2%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4–5.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Squalane~3.7–5.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Shorea stenoptera seed butter~2.7–4.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and can be helpful in restoring the skin barrier function

More about Shorea stenoptera seed butter
Caprylic/capric triglyceride~2.1–3.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
C12-16 alcohols~1.6–2.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin and improve the product's texture

More about C12-16 alcohols
Sodium acrylates copolymer~1.2–1.8%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Ectoin~1.1–1.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Jojoba esters~1–1.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Acetyl hexapeptide-8~0.8–1.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Magnesium chloride~0.5–1.15%
Formula
Irritation risk
Low

Helps thicken the product formulation

More about Magnesium chloride
Palmitic acid~0.45–1.05%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Hydrogenated lecithin~0.35–0.85%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.2–0.75%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Lecithin~0.3–0.75%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Sorbitan isostearate~0.15–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Tocopherol~0.1–0.45%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Caprylyl glycol~0.1–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ethylhexylglycerin~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Phenoxyethanol~0.05–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sodium gluconate~0.01–0.1%
Formula
Irritation risk
Low

Helps stabilize product formulations

More about Sodium gluconate
Ingredient list view

Water, Glycerin, Squalane, Shorea stenoptera seed butter, Caprylic/capric triglyceride, C12-16 alcohols, Sodium acrylates copolymer, Ectoin, Jojoba esters, Acetyl hexapeptide-8, Magnesium chloride, Palmitic acid, Hydrogenated lecithin, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Lecithin, Sorbitan isostearate, Tocopherol, Caprylyl glycol, Ethylhexylglycerin, Phenoxyethanol, Sodium gluconate

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Amazon USPrice as of 10/18/2026 15:30 GMT
$70.00
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Biossance
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
BiossanceSqualane + Ectoin Overnight RescueYOUR PRODUCTBaleaBeauty Expert Day Cream 3% Peptid-Solution 1% EctoinJordan SamuelThe Performance CreamPaula's choiceCalm Rescue and Repair Weightless Moisturiser
Match—56%53%53%
Price$70.00$8.49−$61.51$38.00−$32.00$44.20−$25.80
Shared key ingredients—5 of 74 of 74 of 7
Key difference—Acetyl Dipeptide-1 Cetyl EsterAcetyl Octapeptide-3Allantoin
Irritancy Low Low Low Low
Drying alcohol————
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Product summary

"Biossance - Squalane + Ectoin Overnight Rescue" is effective for: Moisturizing

This moisturizer could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • This moisturizer also contains Peptides (acetyl hexapeptide-8 0.80% - 1.20%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

About the brand

According to Cruelty-Free Kitty "Biossance" is cruelty free and so is its parent company.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 4 studies and safety reviews.

  1. 1
  2. 2
  3. 3
    Vitamin E in dermatologyncbi.nlm.nih.gov
  4. 4
    Vitamin E and Skin Healthlpi.oregonstate.edu
Biossance Squalane + Ectoin Overnight Rescue
BiossanceSqualane + Ectoin Overnight Rescue

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.