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ALASTIN Skincare C-Radical Defense Antioxidant Serum
ALASTIN Skincare

ALASTIN Skincare C-Radical Defense Antioxidant Serum

Efficacy50/100IrritancyMedium
See all ingredients

Works for

Moisturizing
Caprylic/capric triglyceride, Glycerin + 16 more
Works

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, carnosine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, helianthus annuus seed oil.

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~7–8.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–5.2%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~2.5–3.1%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~1.6–2%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~1.4–1.7%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.9–1.1%
CarnosineKey active· HumectantEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.5–0.75%
Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.5–0.8%
Dunaliella salina extractKey activeEffect: MediumA green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin~0.35–0.6%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.5%
Tremella fuciformis sporocarp extractKey active· HumectantEffect: HighMushroom extract that helps attract water to the upper layer of the skin~0.3–0.5%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.3–0.6%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.2–0.4%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~0.2–0.35%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.6–0.85%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.5%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.5%
Anti-aging
Centella asiatica extract, Carnosine + 3 more
May help
What the product description says
“Helps brighten skin and reduce the appearance of fine lines, wrinkles, photodamage , and other signs of aging .”
Source: Alastin

This product contains carnosine, centella asiatica extract. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.5–0.8%
CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.5–0.75%
UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~1.6–2%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.6–0.85%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.5%
Evens skin tone
Camellia sinensis leaf extract
Not delivered
What the product description says
“Works to help refine skin texture and reduce the appearance of redness and brown spots .”
Source: Alastin

Effective ingredients missing or their concentration is too low

Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.6–0.85%
Anti-oxidation
Side benefit · Ubiquinone, Camellia sinensis leaf extract + 11 more
Works well

This product contains antioxidants (carnosine, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - camellia sinensis leaf extract, centella asiatica extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~1.6–2%
Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.6–0.85%
CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.5–0.75%
Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.5–0.8%
Zingiber officinale root extractEffect: LowA plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking~0.45–0.65%
Dunaliella salina extractEffect: LowA green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin~0.35–0.6%
Olea europaea leaf extractEffect: LowA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing~0.35–0.65%
Tremella fuciformis sporocarp extractEffect: LowMushroom extract that helps attract water to the upper layer of the skin~0.3–0.5%
Punica granatum fruit extractEffect: LowA fruit extract that is used to add a fragrance to the product. It might have some antioxidant properties~0.3–0.55%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.25–0.5%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.25–0.45%
ErgothioneineUnder-dosedCan help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking~0.4–0.6%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.5%

Can it cause trouble?

Irritancy
1 strong irritant: Zingiber officinale root extract
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Zingiber officinale root extractA plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lackingHigh~0.45–0.65%est.
Punica granatum fruit extractA fruit extract that is used to add a fragrance to the product. It might have some antioxidant propertiesHigh~0.3–0.55%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~7–8.5%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~3–3.7%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.65–1%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.5–0.8%est.
Olea europaea leaf extractA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missingMedium~0.35–0.65%est.
Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.3–0.5%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.45%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.
EthylhexylglycerinA preservativeMedium~0.1–0.25%est.
Caprylhydroxamic acidA preservativeMedium~0.1–0.15%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.1%est.
Potassium sorbateA preservativeMedium~0.1–0.2%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~7–8.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glycerin~4.3–5.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Sodium acrylates copolymer~3–3.7%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Squalane~2.5–3.1%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Sodium ascorbate~1.9–2.3%
Formula
Irritation risk
Low
More about Sodium ascorbate
Ubiquinone~1.6–2%
Key active
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone
Ectoin~1.4–1.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Physalis angulata extract~1.2–1.4%
Formula
Irritation risk
Low
More about Physalis angulata extract
Betaine~0.9–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Phosphatidylcholine~0.65–1%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
Camellia sinensis leaf extract~0.6–0.85%
Key active
Irritation risk
Low
Works for
AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Carnosine~0.5–0.75%
Key active
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine
Centella asiatica extract~0.5–0.8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Reduces irritationAnti-inflammatoryReduces rednessMoisturizingAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Olea europaea leaf extract~0.35–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing

More about Olea europaea leaf extract
Zingiber officinale root extract~0.45–0.65%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking

More about Zingiber officinale root extract
Ergothioneine~0.4–0.6%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking

More about Ergothioneine
Dunaliella salina extract~0.35–0.6%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

A green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin

More about Dunaliella salina extract
Punica granatum fruit extract~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A fruit extract that is used to add a fragrance to the product. It might have some antioxidant properties

More about Punica granatum fruit extract
Bisabolol~0.25–0.5%
Formula
Irritation risk
Low
Works for
Reduces irritationAnti-inflammatoryAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Lactoferrin~0.3–0.5%
Formula
Irritation risk
Low
More about Lactoferrin
Tremella fuciformis sporocarp extract~0.3–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

Mushroom extract that helps attract water to the upper layer of the skin

More about Tremella fuciformis sporocarp extract
Polyglyceryl-10 laurate~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate
Cetyl alcohol~0.3–0.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Sodium benzoate~0.25–0.5%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Xanthan gum~0.3–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Tocopherol~0.25–0.5%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Helianthus annuus seed oil~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Propanediol~0.25–0.5%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Tocopheryl acetate~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Caprylyl glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Mannitol~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Lecithin~0.25–0.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Phenoxyethanol~0.15–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
C12-15 alkyl benzoate~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Ethylhexylglycerin~0.1–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Caprylhydroxamic acid~0.1–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Caprylhydroxamic acid
Citric acid~0.05–0.1%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Potassium sorbate~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Ingredient list view

Water, Caprylic/capric triglyceride, Glycerin, Sodium acrylates copolymer, Squalane, Sodium ascorbate, Ubiquinone, Ectoin, Physalis angulata extract, Betaine, Phosphatidylcholine, Camellia sinensis leaf extract, Carnosine, Centella asiatica extract, Olea europaea leaf extract, Zingiber officinale root extract, Ergothioneine, Dunaliella salina extract, Punica granatum fruit extract, Bisabolol, Lactoferrin, Tremella fuciformis sporocarp extract, Polyglyceryl-10 laurate, Cetyl alcohol, Sodium benzoate, Xanthan gum, Tocopherol, Helianthus annuus seed oil, Propanediol, Tocopheryl acetate, Caprylyl glycol, Mannitol, Lecithin, Phenoxyethanol, C12-15 alkyl benzoate, Ethylhexylglycerin, Caprylhydroxamic acid, Citric acid, Potassium sorbate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ALASTIN SkincareC-Radical Defense Antioxidant SerumYOUR PRODUCTINNBEAUTY PROJECTElastic Skin Firming & Plumping Vegan Growth Factor Serum with Copper PeptidesFormulystAnti-Aging ConcentrateDr. Barbara SturmThe Good C Vitamin C Serum
Match—40%39%39%
Price$218.00$52.00−$166.00—$144.72−$73.28
Shared key ingredients—9 of 156 of 155 of 15
Key difference—NiacinamideAlpha-ArbutinPanthenol
Irritancy Medium Medium Low Low
Drying alcohol————
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Product summary

"Alastin - C-Radical Defense Antioxidant Serum" could be helpful for: Anti-aging and Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Humectants (mannitol 0.20% - 0.40%, tremella fuciformis sporocarp extract 0.30% - 0.50%, carnosine 0.50% - 0.75%, betaine 0.90% - 1.10% and glycerin 4.30% - 5.20%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 218.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 25 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Final Report on the Safety Assessment of Acrylates Copolymer and 33 Related Cosmetic Ingredientsjournals.sagepub.com
  3. 3
    Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and l-carnosine in ophthalmic and skin care productssciencedirect.com
  4. 4
    Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Modelmdpi.com
  5. 5
    Centella asiatica in cosmetologyncbi.nlm.nih.gov
  6. 6
    Triterpene Composition and Bioactivities of Centella asiatica mdpi.com
ALASTIN Skincare C-Radical Defense Antioxidant Serum
ALASTIN SkincareC-Radical Defense Antioxidant Serum
Buy at Alastin$218.00Amazon

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Alastin$218.00Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.