Works for:
based on ingredients and %- Moisturizing
- Anti-aging
- Anti-oxidation
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"ADVANCED CLINICALS - Peptide Serum" is effective for: Moisturizing
This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- Peptides (pentapeptide-18 0.55% - 1.25%, palmitoyl tripeptide-37 0.40% - 0.95%, palmitoyl tripeptide-1 1.20% - 1.80%, palmitoyl tetrapeptide-7 1.00% - 1.50% and acetyl hexapeptide-8 1.30% - 2.00%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Humectants (soluble collagen 0.10% - 0.50%, sodium hyaluronate 1.60% - 2.30%, glycerin 3.80% - 5.70% and acetyl hexapeptide-8 1.30% - 2.00%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
What our users say
Based on 1 review 100% recommend this product- When it comes to comedogenicity, the reviewer found that it does not clog pores.
- When it comes to using this sunscreen under makeup, the user found that it pills under a foundation.
Price
The product retails for 11.95$ in the United States and for 19.79A$ in Australia.
For a detailed price comparison: click here.
Works for
Moisturizing
What does the product description say?
Results Instantly, Aquaspheres increase hydration levels by 88%.
Source: Iherb Australia
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-37, pentapeptide-18
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Can have some moisturizing properties due to its sugar content
Helps soften the upper layer of the skin and create a nice product texture
Helps preserve products and creates a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Helps soften the upper layer of the skin
A plant extract that can help neutralize free radicals in skin and attract water to its upper layer
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
Might be helpful in neutralizing free radicals in skin but solid research is lacking. Helps attract water to the upper layer of the skin
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Anti-aging
What does the product description say?
Technology Features 6x powerful peptides, proven to diminish the look of premature aging.
Source: Iherb Australia
This product contains acetyl hexapeptide-8, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-37, pentapeptide-18. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A plant extract that can help neutralize free radicals in skin and attract water to its upper layer
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
Anti-oxidation
This product contains antioxidants (punica granatum extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
Can have some moisturizing properties due to its sugar content
A plant extract that might help neutralize free radicals in skin
A plant extract that might have some anti-oxidant properties. Can be used as a fragrance
A plant extract that can have some anti-oxidant effect in skin
A berry extract. Might have some anti-oxidant properties
A plant extract that can help neutralize free radicals in skin and attract water to its upper layer
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Anti-aging |
Total Promises Fulfilled score: 87/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
User reviews (1)
Averages from community submissions.
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 ADVANCED CLINICALS Peptide Serum | Current | $11.95 | |
 Formulyst Anti-Wrinkle Peptide Serum | 56% | - | |
PotentLift Advanced Multi Peptide Complex Serum | 56% | $39.00 | |
 NourishMax Multi Peptide Serum | 56% | $49.00 | |
ClarityRx Get Fit™ Multi-Peptide Healthy Skin Serum | 56% | $112.00 | |
 Sanitas PeptiDerm Firming Serum | 55% | $174.00 |
Key Actives
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps soften the upper layer of the skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Potential irritants
A berry extract. Might have some anti-oxidant properties
A plant extract that might have some anti-oxidant properties. Can be used as a fragrance
An aromatic blend of unspecified and possibly irritating ingredients
Can have some moisturizing properties due to its sugar content
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
A plant extract that might help neutralize free radicals in skin
A plant extract that can have some anti-oxidant effect in skin
A plant extract that can help neutralize free radicals in skin and attract water to its upper layer
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Might be helpful in neutralizing free radicals in skin but solid research is lacking. Helps attract water to the upper layer of the skin
Helps preserve products and creates a nice product texture
Can work as an exfoliant but is typically used to adjust the product pH
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Can have some moisturizing properties due to its sugar content
Helps soften the upper layer of the skin and create a nice product texture
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
A plant extract that might help neutralize free radicals in skin
A berry extract. Might have some anti-oxidant properties
A plant extract that can have some anti-oxidant effect in skin
A plant extract that can help neutralize free radicals in skin and attract water to its upper layer
A plant extract that might have some anti-oxidant properties. Can be used as a fragrance
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Might be helpful in neutralizing free radicals in skin but solid research is lacking. Helps attract water to the upper layer of the skin
A preservative. It helps prevent bacterial growth in cosmetic products
An aromatic blend of unspecified and possibly irritating ingredients
Helps preserve products and creates a nice product texture
Can work as an exfoliant but is typically used to adjust the product pH
Ingredient list view
Water, Glycerin, Pyrus malus fruit extract, Peg-12 dimethicone, Aloe barbadensis leaf juice, Sodium hyaluronate, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Pentapeptide-18, Palmitoyl tripeptide-37, Chenopodium quinoa seed extract, Rosa damascena bud extract, Soluble collagen, Butylene glycol, Carbomer, Centella asiatica extract, Camellia sinensis leaf extract, Punica granatum extract, Rubus fruticosus fruit extract, Coffea robusta seed extract, Vaccinium macrocarpon fruit extract, Vitis vinifera leaf extract, Euterpe oleracea fruit extract, Arctostaphylos uva-ursi leaf extract, Lycium barbarum fruit extract, Morinda citrifolia fruit extract, Rubus idaeus fruit, Aristotelia chilensis fruit extract, Polysorbate 20, Tetrasodium glutamate diacetate, Tocopheryl acetate, Brassica oleracea acephala leaf extract, Xanthan gum, Phenoxyethanol, Parfum, Caprylyl glycol, Ethylhexylglycerin, Hexylene glycol, Citric acid
- Glycerol and the skin: holistic approach to its origin and functions
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model
- Centella asiatica in cosmetology
- Triterpene Composition and Bioactivities of Centella asiatica
- Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts
- Assessment report on Centella asiatica (L.) Urban, herba
- Contact dermatitis due to Madecassol
- The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
- Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation
- Topical microemulsion containing Punica granatum extract: its control over skin erythema and melanin in healthy Asian subjects
- Safety Assessment of Punica granatum -Derived Ingredients as Used in Cosmetics
- Total Oxidant Scavenging Capacity of Euterpe oleracea Mart. (Açaí) Seeds and Identification of Their Polyphenolic Compounds
- Euterpe oleracea, Matricaria chamomilla, and Camellia sinensis as promising ingredients for development of skin care formulations
- Water-soluble polysaccharide from dried Lycium barbarum fruits: Isolation, structural features and antioxidant activity
- Lycium barbarum polysaccharide protects human keratinocytes against UVB-induced photo-damage
- Lycium Barbarum and Human Health