ADVANCED CLINICALS Peptide Serum
Works for
MoisturizingPalmitoyl tripeptide-37, Palmitoyl tripeptide-1 + 13 moreWorks well
“The lightweight formula hydrates and softens fine lines, leaving skin refreshed, radiant, and rejuvenated.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-37
Anti-agingPalmitoyl tripeptide-37, Centella asiatica extract + 3 moreMay help
“Visibly softens the look of wrinkles and fine lines”
This product contains centella asiatica extract, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-37. There is some human evidence that these ingredients help reduce and prevent fine lines and wrinkles and improve skin elasticity and firmness, though it is smaller or less consistent than the evidence for the best anti-aging ingredients.
Anti-oxidationSide benefit · Camellia sinensis leaf extract, Centella asiatica extract + 2 moreMay help
This product contains antioxidants (camellia sinensis leaf extract, centella asiatica extract) that can help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is some human evidence for this effect in skin, though it is smaller or less consistent than the evidence for the best antioxidants.
Can it cause trouble?
Irritancy2 strong irritants: Rosa damascena flower extract, ParfumMedium risk
ComedogenicClean of flagged comedogenic ingredientsNone flagged
User reviews
1 of 1 community members would buy it again.
Ingredients
Filter by role to see what each ingredient is doing.
Water~40–60%
Glycerin~4.4–6.6%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinPyrus malus fruit extract~3.7–5.5%
- Irritation risk
- Medium
Can have some moisturizing properties due to its sugar content
More about Pyrus malus fruit extractPeg-12 dimethicone~2.7–4%
- Irritation risk
- Low
Helps soften the upper layer of the skin and create a nice product texture
More about Peg-12 dimethiconeSoluble collagen~2–3.1%
- Irritation risk
- Low
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
More about Soluble collagenSodium hyaluronate~1.6–2.4%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateAloe barbadensis leaf juice powder~1.4–2.1%
- Irritation risk
- Medium
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
More about Aloe barbadensis leaf juice powderRosa damascena flower extract~1.2–1.8%
Chenopodium quinoa seed extract~1–1.5%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Chenopodium quinoa seed extractCamellia sinensis leaf extract~0.8–1.2%
- Irritation risk
- Low
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
More about Camellia sinensis leaf extractCentella asiatica extract~0.4–1%
- Irritation risk
- Medium
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
More about Centella asiatica extractPalmitoyl tripeptide-37~0.4–0.95%
Palmitoyl tripeptide-1~0.4–0.95%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-1Palmitoyl tetrapeptide-7~0.35–0.85%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tetrapeptide-71,2-hexanediol~0.3–0.7%
Carbomer~0.3–0.75%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerButylene glycol~0.3–0.7%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolXanthan gum~0.2–0.75%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumTocopheryl acetate~0.15–0.7%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetatePhenoxyethanol~0.15–0.6%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolCaprylyl glycol~0.15–0.6%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolParfum~0.1–0.4%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumHexylene glycol~0.1–0.4%
- Irritation risk
- Medium
Helps create a more spreadable product texture
More about Hexylene glycolEthylhexylglycerin~0.1–0.4%
Tetrasodium glutamate diacetate~0.1–0.35%
- Irritation risk
- Low
Helps stabilize the product formulation
More about Tetrasodium glutamate diacetateCitric acid~0.1–0.3%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidSodium benzoate~0.05–0.25%
Polysorbate 20~0.05–0.25%
Sodium lactate~0.05–0.15%
- Irritation risk
- Medium
Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product
More about Sodium lactateSodium citrate~0.01–0.05%
- Irritation risk
- Medium
Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products
More about Sodium citrateIngredient list view
Water, Glycerin, Pyrus malus fruit extract, Peg-12 dimethicone, Soluble collagen, Sodium hyaluronate, Aloe barbadensis leaf juice powder, Rosa damascena flower extract, Chenopodium quinoa seed extract, Camellia sinensis leaf extract, Centella asiatica extract, Palmitoyl tripeptide-37, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, 1,2-hexanediol, Carbomer, Butylene glycol, Xanthan gum, Tocopheryl acetate, Phenoxyethanol, Caprylyl glycol, Parfum, Hexylene glycol, Ethylhexylglycerin, Tetrasodium glutamate diacetate, Citric acid, Sodium benzoate, Polysorbate 20, Sodium lactate, Sodium citrate
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| ADVANCED CLINICALSPeptide SerumYOUR PRODUCT | SkincallDaily Triple Serum | NulastinSKIN Dermal Rejuvenating Serum | FormulystAnti-Aging Concentrate | |
|---|---|---|---|---|
| Match | — | 56% | 55% | 54% |
| Price | $11.95 | — | $115.00+$103.05 | — |
| Shared key ingredients | — | 6 of 10 | 5 of 10 | 5 of 10 |
| Key difference | — | Arginine/Lysine Polypeptide | Acetyl Hexapeptide-8 | Alpha-Arbutin |
| Irritancy | Medium | Low | Low | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: NIDA Salmon PDRN Peptide SerumDr. Whitney Bowe Beauty P46 Peptide + HA Plumping Serum
Product summary
"ADVANCED CLINICALS - Peptide Serum" is effective for: Moisturizing
This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.
Ingredient callouts
- Peptides (pentapeptide-18 0.55% - 1.25%, palmitoyl tripeptide-37 0.40% - 0.95%, palmitoyl tripeptide-1 1.20% - 1.80%, palmitoyl tetrapeptide-7 1.00% - 1.50% and acetyl hexapeptide-8 1.30% - 2.00%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Humectants (soluble collagen 0.10% - 0.50%, sodium hyaluronate 1.60% - 2.30%, glycerin 3.80% - 5.70% and acetyl hexapeptide-8 1.30% - 2.00%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
What our users say
Based on 1 review 100% recommend this product- When it comes to comedogenicity, the reviewer found that it does not clog pores.
- When it comes to using this sunscreen under makeup, the user found that it pills under a foundation.
Price
The product retails for 11.95$ in the United States and for 19.79A$ in Australia.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.
- 1
- 2Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
- 3
- 4
- 5Centella asiatica in cosmetologyncbi.nlm.nih.gov
- 6
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